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COMPLETED Phase 2

S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma

NCT00109928 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Drugs used in chemotherapy, such as cisplatin, etoposide, gemcitabine, and methylprednisolone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating patients with newly diagnosed stage II, stage III, or stage IV T-cell non-Hodgkin's lymphoma.

Conditions Studied

Interventions

  • DRUG cisplatin
  • DRUG methylprednisolone
  • DRUG gemcitabine
  • DRUG etoposide

Study Locations (20)

California

  • Kaiser Permanente - Fremont — Fremont
  • Kaiser Permanente Medical Center - Hayward — Hayward
  • Kaiser Permanente Medical Center - Oakland — Oakland
  • South Sacramento Kaiser-Permanente Medical Center — Sacramento
  • Kaiser Permanente Medical Center - San Francisco Geary Campus — San Francisco
  • Kaiser Permanente Medical Center - Santa Teresa — San Jose
  • Kaiser Foundation Hospital - San Rafael — San Rafael
  • Kaiser Permanente Medical Center - Santa Clara Kiely Campus — Santa Clara
  • Kaiser Permanente Medical Center - Santa Rosa — Santa Rosa
  • Kaiser Permanente Medical Center - South San Francisco — South San Francisco
  • Kaiser Permanente Medical Facility - Stockton — Stockton
  • Kaiser Permanente Medical Center - Vallejo — Vallejo
  • Kaiser Permanente Medical Center - Walnut Creek — Walnut Creek

Illinois

  • Decatur Memorial Hospital Cancer Care Institute — Decatur
  • Cardinal Bernardin Cancer Center at Loyola University Medical Center — Maywood
  • Regional Cancer Center at Memorial Medical Center — Springfield

Arizona

  • Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson

Arkansas

  • Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock

Connecticut

  • Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center — Hartford

Florida

  • M.D. Anderson Cancer Center at Orlando — Orlando

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2005-09
Est. Completion 2014-04
Phase Phase 2

Sponsor

SWOG Cancer Research Network

212 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00109928

The ClinicalTrials.gov registry entry for NCT00109928 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 212 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lymphoma appearing as the primary indexed condition, and to 4 interventions — of which cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00109928 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Illinois, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00109928 about?

NCT00109928 is a clinical study titled "S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma". RATIONALE: Drugs used in chemotherapy, such as cisplatin, etoposide, gemcitabine, and methylprednisolone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cance...

What is the current status of trial NCT00109928?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2005-09. Estimated completion is 2014-04.

What conditions does trial NCT00109928 study?

This clinical trial studies the following conditions: Lymphoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00109928?

The interventions under investigation include: cisplatin (DRUG), methylprednisolone (DRUG), gemcitabine (DRUG), etoposide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00109928?

This trial is sponsored by SWOG Cancer Research Network, which has 212 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00109928 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial