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NCT00410657 · ClinicalTrials.gov registry record · Phase 2

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

A Phase 2 study of Breast Cancer and Lymphoma, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
Phase 2
Development phase
53
Enrollment target
1
Study location

NCT00410657 is a Phase 2 study of Breast Cancer and Lymphoma that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 53 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00410657, a Phase 2 study of Breast Cancer and Lymphoma, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
53 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Alemtuzumab and glucocorticoids, such as prednisone or methylprednisolone, may be an effective treatment for acute graft-versus-host disease caused by a donor stem cell transplant. PURPOSE: This phase II trial is studying how well giving alemtuzumab together with glucocorticoids works in treating newly diagnosed acute graft-versus-host disease in patients who have undergone donor stem cell transplant.

Interventions

  • DRUG prednisone
  • DRUG methylprednisolone
  • BIOLOGICAL alemtuzumab
  • OTHER flow cytometry
  • OTHER immunologic technique

Study Locations (1)

Washington

  • Fred Hutchinson Cancer Research Center - Seattle

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2006-07
Phase Phase 2

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00410657

The ClinicalTrials.gov registry entry for NCT00410657 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which prednisone is the first listed.

NCT00410657 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT00410657 about?

NCT00410657 is a clinical study titled "Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant". RATIONALE: Alemtuzumab and glucocorticoids, such as prednisone or methylprednisolone, may be an effective treatment for acute graft-versus-host disease caused by a donor stem cell transplant. PURPOSE: This phase II trial is studying how well giving alemtuzumab together with glucocorticoids works in...

What is the current status of trial NCT00410657?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 2006-07.

What conditions does trial NCT00410657 study?

This clinical trial studies the following conditions: Breast Cancer, Lymphoma, Leukemia, Myelodysplastic Syndromes, Neuroblastoma.

What interventions are being tested in trial NCT00410657?

The interventions under investigation include: prednisone (DRUG), methylprednisolone (DRUG), alemtuzumab (BIOLOGICAL), flow cytometry (OTHER), immunologic technique (OTHER).

Who is sponsoring clinical trial NCT00410657?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00410657 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.