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NCT00109993 · ClinicalTrials.gov registry record · Phase 2
Campath-1H + FK506 and Methylprednisolone for GVHD
A Phase 2 study of Breast Cancer and Lymphoma, sponsored by Case Comprehensive Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 34
- Enrollment target
- 6
- Study locations
NCT00109993: Completed Phase 2 study of Breast Cancer and Lymphoma, sponsored by Case Comprehensive Cancer Center.
NCT00109993 is a Phase 2 study of Breast Cancer and Lymphoma that has completed, run by Case Comprehensive Cancer Center. The registered enrollment target is 34 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 6 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00109993, a Phase 2 study of Breast Cancer and Lymphoma, has completed, sponsored by Case Comprehensive Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 34 participants
- Enrollment target
- 6
- Study locations
Study Summary
RATIONALE: Alemtuzumab, tacrolimus, and methylprednisolone may be an effective treatment for graft-versus-host disease caused by a donor stem cell transplant. PURPOSE: This phase II trial is studying how well giving alemtuzumab together with tacrolimus and methylprednisolone works in treating acute graft-versus-host disease in patients who have undergone donor stem cell transplant.
Conditions Studied
Interventions
- DRUG methylprednisolone
- DRUG tacrolimus
- BIOLOGICAL alemtuzumab
Study Locations (6)
Ohio
- Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center - Cleveland
- Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center - Cleveland
New York
- Mt. Sinai Medical Center - New York
Oregon
- Oregon Health Sciences University - Portland
Pennsylvania
- Western Pennsylvania Hospital - Pittsburgh
Texas
- Texas Transplant Institute - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2005-01 |
| Est. Completion | 2007-05 |
| Phase | Phase 2 |
What the finished NCT00109993 record still lists
NCT00109993 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which methylprednisolone is the first listed.
NCT00109993 lists 6 locations in 5 states (Ohio, New York, Oregon).
Frequently Asked Questions
What is clinical trial NCT00109993 about?
NCT00109993 is a clinical study titled "Campath-1H + FK506 and Methylprednisolone for GVHD". RATIONALE: Alemtuzumab, tacrolimus, and methylprednisolone may be an effective treatment for graft-versus-host disease caused by a donor stem cell transplant. PURPOSE: This phase II trial is studying how well giving alemtuzumab together with tacrolimus and methylprednisolone works in treating acute...
What is the current status of trial NCT00109993?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2005-01. Estimated completion is 2007-05.
What conditions does trial NCT00109993 study?
This clinical trial studies the following conditions: Breast Cancer, Lymphoma, Leukemia, Myelodysplastic Syndromes, Neuroblastoma.
What interventions are being tested in trial NCT00109993?
The interventions under investigation include: methylprednisolone (DRUG), tacrolimus (DRUG), alemtuzumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00109993?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00109993 being conducted?
This trial has 6 study locations across New York, Ohio, Oregon, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00109993's enrollment target sits among peer trials
34 928th of 1224 higher than 291 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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