Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)
NCT00086125 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this phase II study is to assess the efficacy of AP23573 in patients with specified relapsed or refractory hematological malignancies.
Conditions Studied
Interventions
- DRUG ridaforolimus
Study Locations (8)
Illinois
- University of Chicago Hospitals, Section of Hematology/Oncology — Chicago
Missouri
- Washington University School of Medicine, Siteman Cancer Center, 4921 Parkview Place — St Louis
New Jersey
- The Cancer Institute of New Jersey — New Brunswick
New York
- New York Presbyterian Hospital, Weill College of Cornell University — New York
North Carolina
- Morris Cancer Center - Duke University Medical Center, Adult Bone Marrow Transplant Clinic — Durham
Ohio
- Gabrail Cancer Center — Canton
Pennsylvania
- Jeane's Hospital of TUHS — Philadelphia
Texas
- MD Anderson Cancer Center — Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 57 participants |
| Start Date | 2004-06 |
| Est. Completion | 2006-06 |
| Phase | Phase 2 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00086125
The ClinicalTrials.gov registry entry for NCT00086125 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 741 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Lymphoma appearing as the primary indexed condition, and to 1 intervention — of which ridaforolimus is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00086125 reports 8 study locations spanning 8 distinct geographic areas — top geographies include Illinois, Missouri, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00086125 about?
NCT00086125 is a clinical study titled "Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)". The purpose of this phase II study is to assess the efficacy of AP23573 in patients with specified relapsed or refractory hematological malignancies.
What is the current status of trial NCT00086125?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 57 participants. The study started on 2004-06. Estimated completion is 2006-06.
What conditions does trial NCT00086125 study?
This clinical trial studies the following conditions: Lymphoma, Leukemia, Myelodysplastic Syndromes, Hematologic Malignancies, Myeloid Metaplasia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00086125?
The interventions under investigation include: ridaforolimus (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00086125?
This trial is sponsored by Merck Sharp & Dohme, which has 741 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00086125 being conducted?
This trial has 8 study locations across Illinois, Missouri, New Jersey, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.