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ClinicalTrials.gov 14 recruiting now official registry

Lymphoma, Non-Hodgkin clinical trials

Every US clinical trial registered for Lymphoma, Non-Hodgkin — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

59 US clinical trials · 14 currently recruiting

The research picture

Lymphoma, Non-Hodgkin has 59 registered US clinical trials, 14 of them open to new participants right now — about 24% of the total.

14
recruiting participants now
24%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
5
top sponsor: National Cancer Institute (NCI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 9,999 participants

Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma and Hodgkin's Disease

Stanford University

NCT00398177

RECRUITING Phase 2 4,200 participants

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

American Society of Clinical Oncology

NCT02693535

RECRUITING 3,000 participants

Family Study of Lymphoproliferative Disorders

Mayo Clinic

NCT00626496

RECRUITING 1,295 participants

Tissue Collection for Studies of Lymph Cancer

National Cancer Institute (NCI)

NCT01676805

RECRUITING 500 participants

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

National Cancer Institute (NCI)

NCT02682667

RECRUITING Phase 1 439 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Janssen Research & Development

NCT05421663

RECRUITING Phase 1 230 participants

DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Dizal Pharmaceuticals

NCT05824585

RECRUITING Phase 1 168 participants

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

OncoNano Medicine

NCT06022029

RECRUITING Phase 1 126 participants

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT05442515

RECRUITING Phase 1 72 participants

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Caribou Biosciences

NCT04637763

RECRUITING Phase 1 38 participants

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

Weill Medical College of Cornell University

NCT05618366

RECRUITING Phase 2 31 participants

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

Abramson Cancer Center at Penn Medicine

NCT06458439

RECRUITING NA 24 participants

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

Dana-Farber Cancer Institute

NCT06923397

RECRUITING Phase 2 20 participants

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

University of Florida

NCT05800210

ACTIVE NOT RECRUITING 992 participants

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers

Memorial Sloan Kettering Cancer Center

NCT00579163

ACTIVE NOT RECRUITING Phase 1 498 participants

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Hoffmann-La Roche

NCT04077723

ACTIVE NOT RECRUITING Phase 1 438 participants

A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)

Celgene

NCT03930953

ACTIVE NOT RECRUITING Phase 1 316 participants

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

Eli Lilly and Company

NCT05024045

ACTIVE NOT RECRUITING Phase 4 297 participants

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pharmacyclics Switzerland

NCT03229200

ACTIVE NOT RECRUITING Phase 2 276 participants

A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

Celgene

NCT04245839

ACTIVE NOT RECRUITING Phase 1 167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Janssen Research & Development

NCT05424822

ACTIVE NOT RECRUITING Phase 1 150 participants

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

Nkarta

NCT05020678

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Bellicum Pharmaceuticals

NCT03301168

ACTIVE NOT RECRUITING Phase 1 108 participants

A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL

Ono Pharmaceutical Co.

NCT05515406

ACTIVE NOT RECRUITING NA 60 participants

Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation

University of Miami

NCT05968963

ACTIVE NOT RECRUITING Phase 1 39 participants

A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

Memorial Sloan Kettering Cancer Center

NCT05540340

ACTIVE NOT RECRUITING Phase 1 38 participants

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

UNC Lineberger Comprehensive Cancer Center

NCT02690545

ACTIVE NOT RECRUITING Phase 2 30 participants

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

University of Alabama at Birmingham

NCT04975555

ACTIVE NOT RECRUITING Phase 3 21 participants

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

Dartmouth-Hitchcock Medical Center

NCT03480360

ACTIVE NOT RECRUITING Phase 2 18 participants

Tandem Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Washington University School of Medicine

NCT00882895

ACTIVE NOT RECRUITING Phase 1 18 participants

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

UNC Lineberger Comprehensive Cancer Center

NCT02663297

ACTIVE NOT RECRUITING Phase 1 8 participants

Autologous/Allogeneic TGFbeta-resistant LMP-specific CTL, Lymphoma (TGF-beta)

Baylor College of Medicine

NCT00368082

COMPLETED 5,000 participants

A Study of Patients With AIDS Syndrome

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001120

COMPLETED 1,340 participants

Genome Expression in Lymphoma, Leukemia and Multiple Myeloma

National Cancer Institute (NCI)

NCT00339963

COMPLETED NA 500 participants

Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma Patients Receiving Antibody Treatment

Stanford University

NCT00398372

COMPLETED Phase 3 250 participants

A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000658

COMPLETED Phase 1 190 participants

A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab

Pfizer

NCT01307267

COMPLETED Phase 1 137 participants

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Merck Sharp & Dohme

NCT03598608

COMPLETED Phase 1 92 participants

Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies

Washington University School of Medicine

NCT00241358

COMPLETED Phase 1 74 participants

A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer

Pfizer

NCT00141297

COMPLETED Phase 2 67 participants

Study Evaluating the Safety and Effectiveness of ABT-510 in Subjects With Refractory Lymphoma

Abbott

NCT00061672

COMPLETED Phase 1 61 participants

Intravenous AMD3100 for Collection of Autologous Peripheral Blood Stem Cells in Patients With Lymphoma

Washington University School of Medicine

NCT00733824

COMPLETED Phase 2 49 participants

Ofatumumab and Bendamustine Followed by Maintenance Ofatumumab for Rituximab Relapsed Indolent B-cell Non-Hodgkin's Lymphoma (B-NHL)

Novartis Pharmaceuticals

NCT01294579

COMPLETED Phase 1 49 participants

IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia

ImmunoGen

NCT01534715

COMPLETED NA 45 participants

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000703

COMPLETED Phase 1 41 participants

Preventing Stem Cell Transplant Complications With a Blood Separator Machine

National Heart, Lung, and Blood Institute (NHLBI)

NCT01866839

COMPLETED Phase 2 40 participants

Mobilization of Stem Cells With Plerixafor, Chemotherapy and G-CSF in Multiple Myeloma or Non-Hodgkin's Lymphoma Patients

Genzyme, a Sanofi Company

NCT00322387

COMPLETED Phase 1 33 participants

Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL

Seagen

NCT00655837

COMPLETED Phase 1 33 participants

Clofarabine for Relapsed or Refractory T-Cell or B-Cell Non-Hodgkin Lymphoma (NHL)

Oncology Specialists, S.C.

NCT00156013

COMPLETED Phase 2 33 participants

Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000801

COMPLETED Phase 1 32 participants

Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma

Triphase Research and Development III

NCT03682796

COMPLETED Phase 2 26 participants

Fludarabine and Rituximab for the Treatment of Marginal Zone Non-Hodgkin's Lymphoma

Dana-Farber Cancer Institute

NCT00117156

COMPLETED 20 participants

A Pilot Study of Non-Hodgkin's Lymphoma: Chemotherapy and Blood Levels of Organochlorines

National Cancer Institute (NCI)

NCT00001571

COMPLETED Phase 1 16 participants

A Safety and Preliminary Efficacy Study of CC-99282 in Combination With Obinutuzumab in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Celgene

NCT04434196

COMPLETED Phase 2 15 participants

Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

Sherif S. Far

NCT01720264

COMPLETED Phase 4 12 participants

Zevalin® Followed by Rituxan® Maintenance in Previously Treated Low Grade Non-Hodgkin's Lymphoma

Biogen

NCT00168727

COMPLETED Phase 1 10 participants

Carfilzomib With Bendamustine and Rituximab in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

University of California, San Francis

NCT02187133

COMPLETED NA

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

Glaxo Wellcome

NCT00002284

COMPLETED Phase 2

Proleukin in Combination With Rituxan in Patients With Intermediate and High-Grade Non-Hodgkin's Lymphoma.

Chiron Corporation

NCT00045864

Phase Distribution

PhaseTrial count
Phase 1 29
Phase 2 13
Phase 3 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lymphoma, Non-Hodgkin Trial Landscape

ClinicalTrials.gov lists 59 US studies indexed under Lymphoma, Non-Hodgkin, and 14 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Lymphoma, Non-Hodgkin shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 42 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Lymphoma, Non-Hodgkin is led by National Cancer Institute (NCI) with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 59 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lymphoma, Non-Hodgkin?

PlainTrial tracks 59 US clinical trials for Lymphoma, Non-Hodgkin, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lymphoma, Non-Hodgkin?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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