Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Delirium: full-pipeline trial registry
24 of 63 indexed Delirium trials are currently recruiting.
Corpus placement: #222 of 28,707 conditions by registered trial count.
63 US clinical trials · 24 currently recruiting · #222 of 28,707 conditions by registered trial count
Delirium: 63 US clinical trials tracked, 24 recruiting.
Delirium is the subject of 63 registered US clinical trials on ClinicalTrials.gov, 24 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 5 of these trials.
Enrollment posture brief
Registry condition delirium
OPEN 24 | RECR 38% | LATE 9 | EARLY 10 | RANK #222 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Behavior, Health (38% recruiting · 21 trials)
Delirium lists 24 open slots (38% of 63 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Delirium on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Delirium recruits in line with its size-band peers.
24 of 63 indexed trials (38.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Delirium trials is spread across many organizations.
Vanderbilt University Medical Center accounts for 5 of 63 trials (7.9%). 39 distinct sponsors appear on at least one study for this condition label.
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Typical Delirium enrolment sits around 135 participants.
Median target enrolment is 135 among the 63 trials that report a genuine target (sentinel values excluded). 21 of those (33.3%) plan for fewer than 100 participants.
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Delirium splits between interventional and observational designs.
44 interventional and 19 observational studies make up this index (69.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
63 total, page 1 of 2
Modifying the Inpatient Environment to Reduce Delirium in Older Adults
Farhaan S. Vahidy
NCT06736951
Behavioral Economic & Staffing Strategies in the ICU
University of Nebraska
NCT06184945
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
University of Michigan
NCT05929703
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
Massachusetts General Hospital
NCT06192615
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
Penn State University
NCT05915377
CTSN Embolic Protection Trial
Icahn School of Medicine at Mount Sinai
NCT06027788
Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors
University of Wisconsin, Madison
NCT05373017
Delirium Reduction With Ramelteon
Centennial Medical Center
NCT05069428
Interventions for Postoperative Delirium: Biomarker-3
University of Wisconsin, Madison
NCT03124303
Automating Delirium Severity in the ICU
Mayo Clinic
NCT06172491
Pervasive Sensing and AI in Intelligent ICU
University of Florida
NCT05127265
Goal-Directed Sedation in Mechanically Ventilated Infants and Children
Vanderbilt University Medical Center
NCT04801589
Ceribell Delirium Data Collection Study
Ceribell
NCT04962815
Neurosteer Bedside Monitoring System
Icahn School of Medicine at Mount Sinai
NCT06718764
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
University of Washington
NCT06411561
Trazodone vs. Quetiapine for the Treatment of ICU Delirium
University of Southern California
NCT05307003
Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department
Ohio State University
NCT06326424
Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
University of Iowa
NCT05461092
Simultaneous Recumbent Cycling and Cognitive Training
University of Missouri, Kansas City
NCT04556227
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Washington University School of Medicine
NCT06969287
Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
M.D. Anderson Cancer Center
NCT05431595
Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care
Boston Medical Center
NCT07137949
VoiceLove Digital Therapy for Delirium in the ICU
The Methodist Hospital Research Institute
NCT07218484
TaVNS for Delirium
Stony Brook University
NCT07258082
Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium
Population Health Research Institute
NCT03928236
Delirium in Children Undergoing Stem Cell Transplantation
Weill Medical College of Cornell University
NCT04937400
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Beth Israel Deaconess Medical Center
NCT04093219
The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors
Vanderbilt University Medical Center
NCT00392795
Vasopressor SAT Study
University of Chicago
NCT03182335
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Vanderbilt University Medical Center
NCT03098459
Intelligent Intensive Care Unit
University of Florida
NCT02465307
SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty
Scripps Health
NCT04247646
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care
M.D. Anderson Cancer Center
NCT03743649
Digital Rehabilitation Environment Augmenting Medical System
University of Florida
NCT03385993
Fundamental Intelligent Building Blocks of the Intensive Care Unit (ICU) of the Future: Intelligent ICU of the Future
University of Florida
NCT03905668
Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer
M.D. Anderson Cancer Center
NCT03021486
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Baylor Research Institute
NCT05999903
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
VA Office of Research and Development
NCT00400062
The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
Vanderbilt University Medical Center
NCT01211522
Investigation of Sleep in the Intensive Care Unit
Massachusetts General Hospital
NCT03355053
The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
Vanderbilt University Medical Center
NCT01739933
e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems
Indiana University
NCT00182832
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
Ohio State University
NCT04068311
Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study
Victor Wang
NCT03832192
Improving the Recovery and Outcome Every Day After the ICU
Indiana University
NCT03095417
Nursing Assistant Intervention to Prevent Delirium in Nursing Homes
Jewish Home & Hospital Lifecare System
NCT02994979
Shaping Anesthetic Techniques to Reduce Post-operative Delirium
Johns Hopkins University
NCT03133845
Anesthetic Depth and Postoperative Delirium Trial - 2
University of California, San Francisco
NCT01983384
Post-Operative Delirium in Elderly Surgical Patients
Johns Hopkins University
NCT00590707
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Indiana University
NCT02213900
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 8 |
| Phase 3 | 6 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Delirium records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Delirium trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Delirium page
63 registered trials, 24 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 24 Delirium trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University Medical Center sponsors the most Delirium trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Delirium condition card totals 63 registered trials; most-linked intervention Dexmedetomidine; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.