Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05824585 · ClinicalTrials.gov registry record · Phase 1

DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

A Phase 1 study of Lymphoma, Non-Hodgkin, sponsored by Dizal Pharmaceuticals.

Recruiting
Registry status
Phase 1
Development phase
230
Enrollment target
5
Study locations

NCT05824585: Recruiting Phase 1 study of Lymphoma, Non-Hodgkin, sponsored by Dizal Pharmaceuticals.

NCT05824585 is a Phase 1 study of Lymphoma, Non-Hodgkin that is actively recruiting participants, run by Dizal Pharmaceuticals. The registered enrollment target is 230 participants, below the 385-participant average among 58 other Lymphoma, Non-Hodgkin trials with a reported enrollment target (40% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05824585, a Phase 1 study of Lymphoma, Non-Hodgkin, is actively recruiting participants, sponsored by Dizal Pharmaceuticals.

RECRUITING
Registry status
Phase 1
Development phase
230 participants
Enrollment target
5
Study locations

Study Summary

This study will treat patients with B-NHL who have relapsed, progressed, or were intolerant to systemic therapy progressed following prior therapy. This study will help to understand what type of side effects may occur with the drug treatment. It will also measure the levels of drug in the body and assess its anti-cancer activity as monotherapy.

Conditions Studied

Interventions

  • DRUG DZD8586

Study Locations (5)

Victoria

  • Research site - Ballarat
  • Research site - Melbourne

New York

  • Research site - New York

New South Wales

  • Research site - Albury

Western Australia

  • Research site - Perth

Trial Details

FieldValue
Enrollment Target 230 participants
Start Date 2023-05-15
Est. Completion 2027-10-30
Phase Phase 1
Dizal Pharmaceuticals

15 total trials

What NCT05824585 shows while recruiting

NCT05824585 is an interventional study that assigns participants to a tested intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, below the 385-participant average among 58 other Lymphoma, Non-Hodgkin trials with a reported enrollment target (40% lower).

The record links to 1 condition, with Lymphoma, Non-Hodgkin appearing as the primary indexed condition, and to 1 intervention - of which DZD8586 is the first listed.

NCT05824585 lists 5 locations in 4 states (Victoria, New York, New South Wales).

Frequently Asked Questions

What is clinical trial NCT05824585 about?

NCT05824585 is a clinical study titled "DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma". This study will treat patients with B-NHL who have relapsed, progressed, or were intolerant to systemic therapy progressed following prior therapy. This study will help to understand what type of side effects may occur with the drug treatment. It will also measure the levels of drug in the body and ...

What is the current status of trial NCT05824585?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 230 participants. The study started on 2023-05-15. Estimated completion is 2027-10-30.

What conditions does trial NCT05824585 study?

This clinical trial studies the following conditions: Lymphoma, Non-Hodgkin.

What interventions are being tested in trial NCT05824585?

The interventions under investigation include: DZD8586 (DRUG).

Who is sponsoring clinical trial NCT05824585?

This trial is sponsored by Dizal Pharmaceuticals, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05824585 being conducted?

This trial has 5 study locations across New York, New South Wales, Victoria, Western Australia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Lymphoma, Non-Hodgkin

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05824585's enrollment target sits among peer trials

230 17th of 58 higher than 42 of 58 other Lymphoma, Non-Hodgkin trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Lymphoma, Non-Hodgkin trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02710253 · 230 participants · Phase 2

    Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

  • NCT02777879 · 230 participants

    Lung Microbiome and Inflammation in Early COPD

  • NCT03824483 · 230 participants · Phase 2

    Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

  • NCT03833622 · 230 participants · NA

    Shared Decision Making to Improve Goals of Care in the ED

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05824585, the US trial registry maintained by the National Library of Medicine. NCT05824585 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.