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NCT05800210 · ClinicalTrials.gov registry record · Phase 2

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

A Phase 2 study of Acute Myeloid Leukemia and Myelodysplastic Syndromes, sponsored by University of Florida.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT05800210 is a Phase 2 study of Acute Myeloid Leukemia and Myelodysplastic Syndromes that is actively recruiting participants, run by University of Florida. The registered enrollment target is 20 participants, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05800210, a Phase 2 study of Acute Myeloid Leukemia and Myelodysplastic Syndromes, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), juvenile myelomonocytic leukemia (JMML), high risk myelodysplastic syndrome (MDS), chronic myeloid leukemia (CML) and lymphoma. Subjects will receive an allogeneic stem cell transplant that has been depleted of ⍺/β CD3+ T-cells and CD19+ B-cells using the Miltenyi CliniMACS Prodigy® system.

Conditions Studied

Acute Myeloid Leukemia Myelodysplastic Syndromes Acute Lymphoblastic Leukemia Lymphoma, Non-Hodgkin Chronic Myeloid Leukemia Juvenile Myelomonocytic Leukemia Lymphoma, Hodgkin

Interventions

  • DEVICE Miltenyi CliniMACS Prodigy ® system

Study Locations (1)

Florida

  • University of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-05-03
Est. Completion 2027-05
Phase Phase 2

Sponsor

University of Florida

1,106 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05800210

The ClinicalTrials.gov registry entry for NCT05800210 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (83% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 1 intervention - of which Miltenyi CliniMACS Prodigy ® system is the first listed.

NCT05800210 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05800210 about?

NCT05800210 is a clinical study titled "Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases". This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), juvenile myelomonocytic leukemia (JMML), high risk myelodysplastic syndr...

What is the current status of trial NCT05800210?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-05-03. Estimated completion is 2027-05.

What conditions does trial NCT05800210 study?

This clinical trial studies the following conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Acute Lymphoblastic Leukemia, Lymphoma, Non-Hodgkin, Chronic Myeloid Leukemia.

What interventions are being tested in trial NCT05800210?

The interventions under investigation include: Miltenyi CliniMACS Prodigy ® system (DEVICE).

Who is sponsoring clinical trial NCT05800210?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05800210 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.