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A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)
NCT03930953 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of CC-99282 alone and in combination with anti-lymphoma agents in participants with relapsed or refractory non-Hodgkin's lymphomas.
Conditions Studied
Interventions
- DRUG Obinutuzumab
- DRUG Rituximab
- DRUG Valemetostat
- DRUG Tafasitamab
- DRUG CC-99282
Study Locations (20)
Other
- Local Institution - 253 — Buenos Aires
- Local Institution - 701 — Salzburg
- Local Institution - 704 — Sankt Pölten
- Local Institution - 703 — Vienna
- Local Institution - 902 — Leuven
- Local Institution - 451 — São Paulo
- Local Institution - 452 — São Paulo
Florida
- Local Institution - 111 — Jacksonville
- Local Institution - 102 — Tampa
Buenos Aires
- Local Institution - 255 — Ciudad Autonoma de Buenos Aires
- Local Institution - 254 — Pilar
Arizona
- Local Institution - 109 — Scottsdale
Kansas
- Local Institution - 108 — Overland Park
Minnesota
- Local Institution - 107 — Rochester
Missouri
- Local Institution - 104 — St Louis
New Jersey
- Local Institution - 103 — Hackensack
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 438 participants |
| Start Date | 2019-05-20 |
| Est. Completion | 2028-02-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03930953
The ClinicalTrials.gov registry entry for NCT03930953 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 438 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Celgene, which has 73 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Lymphoma, Non-Hodgkin appearing as the primary indexed condition, and to 5 interventions — of which Obinutuzumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03930953 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, Florida, Buenos Aires. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03930953 about?
NCT03930953 is a clinical study titled "A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)". The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of CC-99282 alone and in combination with anti-lymphoma agents in participants with relapsed or refractory non-Hodgkin's lymphomas.
What is the current status of trial NCT03930953?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 438 participants. The study started on 2019-05-20. Estimated completion is 2028-02-09.
What conditions does trial NCT03930953 study?
This clinical trial studies the following conditions: Lymphoma, Non-Hodgkin. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03930953?
The interventions under investigation include: Obinutuzumab (DRUG), Rituximab (DRUG), Valemetostat (DRUG), Tafasitamab (DRUG), CC-99282 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03930953?
This trial is sponsored by Celgene, which has 73 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03930953 being conducted?
This trial has 20 study locations across Arizona, Florida, Kansas, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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