Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members
NCT00000703 · View on ClinicalTrials.gov ↗
Study Summary
To determine the safety and effectiveness of a combination chemotherapy-radiation-zidovudine (AZT) treatment for patients with peripheral lymphoma. Other chemotherapies have been tried in patients with AIDS related lymphomas, but the results have not been satisfactory. This study will show whether the combination of chemotherapy, radiation, and AZT is more effective and less toxic than previously used treatments.
Conditions Studied
Interventions
- DRUG Cyclophosphamide
- DRUG Allopurinol
- DRUG Doxorubicin hydrochloride
- DRUG Bleomycin sulfate
- DRUG Vincristine sulfate
Study Locations (14)
New York
- Bellevue Hosp / New York Univ Med Ctr — New York
- Saint Luke's - Roosevelt Hosp Ctr — New York
- Mount Sinai Med Ctr — New York
- Univ of Rochester Medical Center — Rochester
California
- Los Angeles County - USC Med Ctr — Los Angeles
- UCLA CARE Ctr — Los Angeles
- San Francisco AIDS Clinic / San Francisco Gen Hosp — San Francisco
Louisiana
- Charity Hosp / Tulane Univ Med School — New Orleans
- Louisiana State Univ Med Ctr / Tulane Med School — New Orleans
- Tulane Univ School of Medicine — New Orleans
District of Columbia
- George Washington Univ Med Ctr — Washington D.C.
Massachusetts
- Univ of Massachusetts Med Ctr — Worcester
Pennsylvania
- Milton S Hershey Med Ctr — Hershey
South Carolina
- Julio Arroyo — West Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Est. Completion | 1990-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00000703
The ClinicalTrials.gov registry entry for NCT00000703 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 1,295 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 5 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00000703 reports 14 study locations spanning 7 distinct geographic areas — top geographies include New York, California, Louisiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00000703 about?
NCT00000703 is a clinical study titled "Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members". To determine the safety and effectiveness of a combination chemotherapy-radiation-zidovudine (AZT) treatment for patients with peripheral lymphoma. Other chemotherapies have been tried in patients with AIDS related lymphomas, but the results have not been satisfactory. This study will show whether ...
What is the current status of trial NCT00000703?
This trial is currently completed. It is a NA study. The enrollment target is 45 participants. Estimated completion is 1990-03.
What conditions does trial NCT00000703 study?
This clinical trial studies the following conditions: HIV Infections, Lymphoma, Non-Hodgkin. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00000703?
The interventions under investigation include: Cyclophosphamide (DRUG), Allopurinol (DRUG), Doxorubicin hydrochloride (DRUG), Bleomycin sulfate (DRUG), Vincristine sulfate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00000703?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 1,295 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00000703 being conducted?
This trial has 14 study locations across California, District of Columbia, Louisiana, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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