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RECRUITING Phase 1

TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

NCT07082803 · View on ClinicalTrials.gov ↗

Study Summary

The primary purpose of this study is to evaluate the safety, pharmacokinetics,, and preliminary anti-tumor activity of TLN-121 as a single agent and in combination with other anti-lymphoma therapies in patients with relapsed or refractory Non-Hodgkin Lymphomas

Interventions

  • DRUG TLN-121
  • DRUG TLN-254

Study Locations (11)

Victoria

  • Cabrini Health — Malvern
  • Peter MacCallum Cancer Centre — Melbourne

California

  • Stanford Medicine Cancer Center — Palo Alto

Michigan

  • The START Center for Cancer Care - Midwest — Grand Rapids

Missouri

  • Washington University School of Medicine — St Louis

Tennessee

  • SCRI Oncology Partners — Nashville

Texas

  • The University of Texas MD Anderson Cancer Center — Houston

New South Wales

  • Macquarie University Hospital — Macquarie Park

Queensland

  • Princess Alexandra Hospital — Woolloongabba

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2025-06-23
Est. Completion 2030-11
Phase Phase 1

Sponsor

Treeline Biosciences

34 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07082803

The ClinicalTrials.gov registry entry for NCT07082803 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Treeline Biosciences, which has 34 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Lymphoma appearing as the primary indexed condition, and to 2 interventions — of which TLN-121 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07082803 reports 11 study locations spanning 10 distinct geographic areas — top geographies include Victoria, California, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07082803 about?

NCT07082803 is a clinical study titled "TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas". The primary purpose of this study is to evaluate the safety, pharmacokinetics,, and preliminary anti-tumor activity of TLN-121 as a single agent and in combination with other anti-lymphoma therapies in patients with relapsed or refractory Non-Hodgkin Lymphomas

What is the current status of trial NCT07082803?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 180 participants. The study started on 2025-06-23. Estimated completion is 2030-11.

What conditions does trial NCT07082803 study?

This clinical trial studies the following conditions: Lymphoma, Lymphoma, Non Hodgkin. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07082803?

The interventions under investigation include: TLN-121 (DRUG), TLN-254 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07082803?

This trial is sponsored by Treeline Biosciences, which has 34 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07082803 being conducted?

This trial has 11 study locations across California, Michigan, Missouri, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial