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NCT07082803 · ClinicalTrials.gov registry record · Phase 1

TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

A Phase 1 study of Lymphoma and Lymphoma, Non-Hodgkin, sponsored by Treeline Biosciences.

Recruiting
Registry status
Phase 1
Development phase
180
Enrollment target
11
Study locations

NCT07082803 is a Phase 1 study of Lymphoma and Lymphoma, Non-Hodgkin that is actively recruiting participants, run by Treeline Biosciences. The registered enrollment target is 180 participants, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (63% lower). The trial reports 11 study locations across 10 states.

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The verdict

NCT07082803, a Phase 1 study of Lymphoma and Lymphoma, Non-Hodgkin, is actively recruiting participants, sponsored by Treeline Biosciences.

RECRUITING
Registry status
Phase 1
Development phase
180 participants
Enrollment target
11
Study locations

Study Summary

The primary purpose of this study is to evaluate the safety, pharmacokinetics,, and preliminary anti-tumor activity of TLN-121 as a single agent and in combination with other anti-lymphoma therapies in patients with relapsed or refractory Non-Hodgkin Lymphomas

Interventions

  • DRUG TLN-121
  • DRUG TLN-254

Study Locations (11)

Victoria

  • Cabrini Health - Malvern
  • Peter MacCallum Cancer Centre - Melbourne

California

  • Stanford Medicine Cancer Center - Palo Alto

Michigan

  • The START Center for Cancer Care - Midwest - Grand Rapids

Missouri

  • Washington University School of Medicine - St Louis

Tennessee

  • SCRI Oncology Partners - Nashville

Texas

  • The University of Texas MD Anderson Cancer Center - Houston

New South Wales

  • Macquarie University Hospital - Macquarie Park

Queensland

  • Princess Alexandra Hospital - Woolloongabba

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2025-06-23
Est. Completion 2030-11
Phase Phase 1

Sponsor

Treeline Biosciences

3 total trials

What the Registry Record Tells You About NCT07082803

The ClinicalTrials.gov registry entry for NCT07082803 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (63% lower). The listed sponsor is Treeline Biosciences, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which TLN-121 is the first listed.

NCT07082803 reports 11 study locations spanning 10 distinct geographic areas - top geographies include Victoria, California, Michigan.

Frequently Asked Questions

What is clinical trial NCT07082803 about?

NCT07082803 is a clinical study titled "TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas". The primary purpose of this study is to evaluate the safety, pharmacokinetics,, and preliminary anti-tumor activity of TLN-121 as a single agent and in combination with other anti-lymphoma therapies in patients with relapsed or refractory Non-Hodgkin Lymphomas

What is the current status of trial NCT07082803?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 180 participants. The study started on 2025-06-23. Estimated completion is 2030-11.

What conditions does trial NCT07082803 study?

This clinical trial studies the following conditions: Lymphoma, Lymphoma, Non-Hodgkin.

What interventions are being tested in trial NCT07082803?

The interventions under investigation include: TLN-121 (DRUG), TLN-254 (DRUG).

Who is sponsoring clinical trial NCT07082803?

This trial is sponsored by Treeline Biosciences, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07082803 being conducted?

This trial has 11 study locations across California, Michigan, Missouri, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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