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NCT04300998 · ClinicalTrials.gov registry record

Study of CAR-T Therapy in Older Patients

A clinical trial of Multiple Myeloma and Lymphoma, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
154
Enrollment target
1
Study location

NCT04300998: Recruiting study of Multiple Myeloma and Lymphoma, sponsored by Memorial Sloan Kettering Cancer Center.

NCT04300998 is a study of Multiple Myeloma and Lymphoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 154 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04300998, a study of Multiple Myeloma and Lymphoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
154 participants
Enrollment target
1
Study location

Study Summary

This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' disease.

Primary Outcome

Participants who complete all assessment visits prior to disease progression or death will be considered as a success for a feasibility endpoint.

Interventions

  • BEHAVIORAL Activities of Daily Living/ADLs
  • BEHAVIORAL Instrumental Activity of Daily Living
  • BEHAVIORAL Timed Up and Go
  • BEHAVIORAL Cognition
  • BEHAVIORAL Geriatric Depression Scale

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 154 participants
Start Date 2020-03-04
Est. Completion 2026-03-04
Memorial Sloan Kettering Cancer Center

1,884 total trials

What NCT04300998 shows while recruiting

NCT04300998 is an observational study that tracks outcomes without assigning an intervention. The registered 154 participants enrollment target is mid-sized for trials with a published cap, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (72% lower).

The record links to 6 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Activities of Daily Living/ADLs is the first listed.

NCT04300998 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT04300998 about?

NCT04300998 is a clinical study titled "Study of CAR-T Therapy in Older Patients". This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' dise...

What is the current status of trial NCT04300998?

This trial is currently recruiting. The enrollment target is 154 participants. The study started on 2020-03-04. Estimated completion is 2026-03-04.

What conditions does trial NCT04300998 study?

This clinical trial studies the following conditions: Multiple Myeloma, Lymphoma, Lymphoma, B-Cell, High Grade B-Cell Lymphoma, Dlbcl NOS.

What interventions are being tested in trial NCT04300998?

The interventions under investigation include: Activities of Daily Living/ADLs (BEHAVIORAL), Instrumental Activity of Daily Living (BEHAVIORAL), Timed Up and Go (BEHAVIORAL), Cognition (BEHAVIORAL), Geriatric Depression Scale (BEHAVIORAL).

Who is sponsoring clinical trial NCT04300998?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04300998 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Multiple Myeloma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04300998's enrollment target sits among peer trials

154 132nd of 438 higher than 307 of 438 other Multiple Myeloma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04300998, the US trial registry maintained by the National Library of Medicine. NCT04300998 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.