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Study of CAR-T Therapy in Older Patients
NCT04300998 · View on ClinicalTrials.gov ↗
Study Summary
This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' disease.
Conditions Studied
Interventions
- BEHAVIORAL Activities of Daily Living/ADLs
- BEHAVIORAL Instrumental Activity of Daily Living
- BEHAVIORAL Timed Up and Go
- BEHAVIORAL Cognition
- BEHAVIORAL Geriatric Depression Scale
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center — New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 154 participants |
| Start Date | 2020-03-04 |
| Est. Completion | 2026-03-04 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04300998
The ClinicalTrials.gov registry entry for NCT04300998 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 154 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 2,280 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 6 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions — of which Activities of Daily Living/ADLs is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04300998 reports 1 study location spanning 1 distinct geographic area — top geographies include New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04300998 about?
NCT04300998 is a clinical study titled "Study of CAR-T Therapy in Older Patients". This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' dise...
What is the current status of trial NCT04300998?
This trial is currently recruiting. The enrollment target is 154 participants. The study started on 2020-03-04. Estimated completion is 2026-03-04.
What conditions does trial NCT04300998 study?
This clinical trial studies the following conditions: Multiple Myeloma, Lymphoma, Lymphoma, B-Cell, High-grade B-cell Lymphoma, DLBCL NOS. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04300998?
The interventions under investigation include: Activities of Daily Living/ADLs (BEHAVIORAL), Instrumental Activity of Daily Living (BEHAVIORAL), Timed Up and Go (BEHAVIORAL), Cognition (BEHAVIORAL), Geriatric Depression Scale (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04300998?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 2,280 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04300998 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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