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ClinicalTrials.gov 88 recruiting now early-phase tilt #21 of 28,707 conditions

Lymphoma: early-phase trial registry

88 of 330 indexed Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #21 of 28,707 conditions by registered trial count.

330 US clinical trials · 88 currently recruiting · #21 of 28,707 conditions by registered trial count

Lymphoma: 330 US clinical trials tracked, 88 recruiting.

Lymphoma is the subject of 330 registered US clinical trials on ClinicalTrials.gov, 88 of them currently open to new participants. 25 are in Phase 3-4 (later-stage) and 229 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 34 of these trials.

Enrollment posture brief

Registry condition lymphoma

OPEN 88 | RECR 27% | LATE 25 | EARLY 229 | RANK #21 | SPON 34

Nearest open-share peer: Age-related Macular Degeneration (27% recruiting · 75 trials)

Ovarian Cancer43.5%Type 2 Diabetes36.6%Lymphoma (this)27%Diabetes25.1%Schizophrenia23.9%
Open-enrollment share among volume-matched conditions near Lymphoma

Lymphoma lists 88 open slots (27% of 330 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lymphoma is recruiting below its size-band peers.

    88 of 330 indexed trials (26.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lymphoma trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 34 of 330 trials (10.3%). 116 distinct sponsors appear on at least one study for this condition label.

  3. Most Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 300 trials that report a genuine target (sentinel values excluded). 213 of those (71%) plan for fewer than 100 participants.

  4. Lymphoma research is mostly interventional.

    299 interventional and 31 observational studies make up this index (90.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1119Phase 2110Phase 322Phase 43

Open and recent trials

330 total, page 2 of 7

RECRUITING Phase 1 50 participants

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Treeline Biosciences

NCT06733441

RECRUITING Phase 2 50 participants

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

M.D. Anderson Cancer Center

NCT05929612

RECRUITING Phase 1 50 participants

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Hoffmann-La Roche

NCT06624085

RECRUITING Phase 2 49 participants

A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

VIVUS

NCT06915246

RECRUITING NA 48 participants

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

Memorial Sloan Kettering Cancer Center

NCT05940272

RECRUITING Phase 2 45 participants

Epco, Zanu, Ritux for R/R FL or MZL

Reid Merryman, MD

NCT06563596

RECRUITING Phase 1 42 participants

A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer

Fox Chase Cancer Center

NCT04827810

RECRUITING Phase 2 41 participants

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

Jennifer Crombie, MD

NCT05800366

RECRUITING NA 40 participants

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Washington University School of Medicine

NCT07226934

RECRUITING NA 40 participants

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

UNC Lineberger Comprehensive Cancer Center

NCT06860880

RECRUITING Phase 2 40 participants

Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.

M.D. Anderson Cancer Center

NCT06218602

RECRUITING Phase 2 40 participants

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

National Cancer Institute (NCI)

NCT03258567

RECRUITING Phase 2 40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Spectrum Pharmaceuticals

NCT04570423

RECRUITING Phase 1 40 participants

Mosunetuzumab for CLL MRD Clearance

Inhye Ahn

NCT07052695

RECRUITING 40 participants

Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

M.D. Anderson Cancer Center

NCT01608152

RECRUITING NA 40 participants

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

Hua-Jay J Cherng, MD

NCT06693830

RECRUITING NA 40 participants

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

University of Utah

NCT07390071

RECRUITING Phase 2 40 participants

Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma

M.D. Anderson Cancer Center

NCT02106988

RECRUITING Phase 2 39 participants

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

Divaya Bhutani

NCT05346809

RECRUITING Phase 2 36 participants

A Phase 2 Trial of Mosunetuzumab and Zanubrutinib for Patients With Relapsed/Refractory Marginal Zone Lymphoma

M.D. Anderson Cancer Center

NCT06563505

RECRUITING Phase 2 35 participants

Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

Beth Israel Deaconess Medical Center

NCT06510361

RECRUITING Phase 2 35 participants

Odronextamab in Low Tumor Volume Advanced FL

Gottfried von Keudell, MD PhD

NCT07128641

RECRUITING Phase 2 33 participants

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

Gottfried von Keudell, MD PhD

NCT06510309

RECRUITING Phase 2 30 participants

A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy

M.D. Anderson Cancer Center

NCT05464719

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING NA 30 participants

Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Stem Cell Transplantation

University of Nebraska

NCT05135351

RECRUITING Phase 2 30 participants

Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

Jennifer Amengual

NCT06954805

RECRUITING 30 participants

Umbilical Cord Blood Transplantation From Unrelated Donors

University of Rochester

NCT03016806

RECRUITING Phase 2 27 participants

A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT07030699

RECRUITING NA 24 participants

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

Dana-Farber Cancer Institute

NCT06923397

RECRUITING Phase 1 21 participants

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Estrella Biopharma

NCT06343311

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

RECRUITING Phase 1 20 participants

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

ITM Solucin

NCT06441331

RECRUITING Phase 1 18 participants

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

St. Jude Children's Research Hospital

NCT06326463

RECRUITING Phase 1 15 participants

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Dana-Farber Cancer Institute

NCT06475235

RECRUITING Phase 1 10 participants

Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

City of Hope Medical Center

NCT05371132

RECRUITING Early Phase 1 8 participants

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06398457

RECRUITING

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Barbara Ann Karmanos Cancer Institute

NCT00935090

ACTIVE NOT RECRUITING 89,655 participants

Agriculture Health Study

National Cancer Institute (NCI)

NCT00352924

ACTIVE NOT RECRUITING Phase 2 373 participants

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Eastern Cooperative Oncology Group

NCT01415752

ACTIVE NOT RECRUITING Phase 1 320 participants

A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.

Glenmark Specialty S.A.

NCT05878691

ACTIVE NOT RECRUITING Phase 2 313 participants

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Center for International Blood and Marrow Transplant Research

NCT06001385

ACTIVE NOT RECRUITING NA 300 participants

Supportive Oncology Care At Home RCT

Massachusetts General Hospital

NCT04544046

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING NA 261 participants

Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study

Fred Hutchinson Cancer Center

NCT04081779

ACTIVE NOT RECRUITING Phase 1 253 participants

Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas

Taiho Oncology

NCT02503423

ACTIVE NOT RECRUITING NA 180 participants

Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma

University of California, Davis

NCT04478318

ACTIVE NOT RECRUITING Phase 3 173 participants

Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant

Children's Oncology Group

NCT03057054

ACTIVE NOT RECRUITING Phase 2 140 participants

Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies

Children's Hospital of Philadelphia

NCT02323867

ACTIVE NOT RECRUITING NA 130 participants

Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer

M.D. Anderson Cancer Center

NCT03141437

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Phase Distribution

PhaseTrial count
Phase 1 119
Phase 2 110
Phase 3 22
Phase 4 3

Named interventions

Most-linked intervention names on Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

cyclophosphamide Drug
30 trials
rituximab Biological
26 trials
Cyclophosphamide Drug
23 trials
Rituximab Drug
21 trials
filgrastim Biological
17 trials
cytarabine Drug
14 trials
etoposide Drug
13 trials
Fludarabine Drug
13 trials

US sites by state

Facility locations filed on Lymphoma trials. A trial with sites in several states counts in each.

California 91 trials
New York 82 trials
Texas 71 trials
Maryland 50 trials
Illinois 50 trials
Massachusetts 47 trials
Florida 45 trials
North Carolina 37 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lymphoma page

330 registered trials, 88 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lymphoma condition card totals 330 registered trials; most-linked intervention cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.