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NCT04898790 · ClinicalTrials.gov registry record · NA
Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant
A NA study of Multiple Myeloma and Lymphoma, sponsored by University of Nebraska.
- Recruiting
- Registry status
- NA
- Development phase
- 88
- Enrollment target
- 1
- Study location
NCT04898790 is a NA study of Multiple Myeloma and Lymphoma that is actively recruiting participants, run by University of Nebraska. The registered enrollment target is 88 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04898790, a NA study of Multiple Myeloma and Lymphoma, is actively recruiting participants, sponsored by University of Nebraska.
- RECRUITING
- Registry status
- NA
- Development phase
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
Cancer and treatment-related cognitive changes, such as thinking or remembering, hinder resumption of normal routine and roles and worsen quality of life. Older adults undergoing hematopoietic cell transplantation (HCT) are at high-risk for cognitive impairment. Age is a risk factor for Alzheimer's Dementia (AD) and the hematological malignancies leading to HCT. There are shared mechanisms and interactions between AD and cancer-related cognitive decline (CRCD). Physical activity improves cognitive function in older adults and survivors of other cancers. This study hypothesizes that increasing physical activity can also improve cognitive function in this vulnerable population. The study has two goals. The first is to adapt and test an evidence-based physical activity intervention, The Community Health Activities Model Program for Seniors II (CHAMPS II), in the HCT setting for adults 55 years and older. This will be done using semi-structured interview of up to 10 patients who have experienced the HCT process within the last 3 to 6 months with HCT care-team partners. The second goal will explore the prevalence and impact of AD-neuropathology and inflammation on cancer-related cognitive decline (CRCD) in older adults undergoing HCT.
Conditions Studied
Interventions
- BEHAVIORAL CHAMPS-II adapted to adults 60+ years in HCT setting
Study Locations (1)
Nebraska
- University of Nebraska Medical Center - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2021-11-18 |
| Est. Completion | 2027-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04898790
The ClinicalTrials.gov registry entry for NCT04898790 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (84% lower). The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 1 intervention - of which CHAMPS-II adapted to adults 60+ years in HCT setting is the first listed.
NCT04898790 reports 1 study location spanning 1 distinct geographic area - top geographies include Nebraska.
Frequently Asked Questions
What is clinical trial NCT04898790 about?
NCT04898790 is a clinical study titled "Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant". Cancer and treatment-related cognitive changes, such as thinking or remembering, hinder resumption of normal routine and roles and worsen quality of life. Older adults undergoing hematopoietic cell transplantation (HCT) are at high-risk for cognitive impairment. Age is a risk factor for Alzheimer's ...
What is the current status of trial NCT04898790?
This trial is currently recruiting. It is a NA study. The enrollment target is 88 participants. The study started on 2021-11-18. Estimated completion is 2027-07.
What conditions does trial NCT04898790 study?
This clinical trial studies the following conditions: Multiple Myeloma, Lymphoma, Leukemia, Myeloproliferative Neoplasm, Myelodysplastic Syndromes (MDS).
What interventions are being tested in trial NCT04898790?
The interventions under investigation include: CHAMPS-II adapted to adults 60+ years in HCT setting (BEHAVIORAL).
Who is sponsoring clinical trial NCT04898790?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04898790 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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