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NCT03823534 · ClinicalTrials.gov registry record · Phase 3
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
A Phase 3 study of Multiple Myeloma and Pain, sponsored by St. Louis University.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT03823534: Recruiting Phase 3 study of Multiple Myeloma and Pain, sponsored by St. Louis University.
NCT03823534 is a Phase 3 study of Multiple Myeloma and Pain that is actively recruiting participants, run by St. Louis University. The registered enrollment target is 60 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03823534, a Phase 3 study of Multiple Myeloma and Pain, is actively recruiting participants, sponsored by St. Louis University.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because no fracture is present, these patients do not rely on inflammatory healing factors, allowing for post-op NSAID use. This study sets out to determine the effect of post-op toradol use in addition to opioids compared to solely opioids in patients undergoing prophylactic nailing of the femur.
Primary Outcome
Measure the effect of post-op ketorolac on the concurrent use of opioid pain medications during post-op days 1-14 following prophylactic IMN of the femur compared to patients treated only with opioids.
Conditions Studied
Interventions
- DRUG Acetaminophen
- DRUG Ketorolac
- DRUG Normal saline
- DRUG Morphine
- DRUG Oxycodone Acetaminophen
Study Locations (1)
Missouri
- Saint Louis University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2019-02-20 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 3 |
What NCT03823534 shows while recruiting
NCT03823534 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (89% lower).
The record links to 5 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Acetaminophen is the first listed.
NCT03823534 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT03823534 about?
NCT03823534 is a clinical study titled "Post-Op Pain Control for Prophylactic Intramedullary Nailing.". Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a uniq...
What is the current status of trial NCT03823534?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2019-02-20. Estimated completion is 2026-12-31.
What conditions does trial NCT03823534 study?
This clinical trial studies the following conditions: Multiple Myeloma, Pain, Lymphoma, Opioid Use, Bone Metastases.
What interventions are being tested in trial NCT03823534?
The interventions under investigation include: Acetaminophen (DRUG), Ketorolac (DRUG), Normal saline (DRUG), Morphine (DRUG), Oxycodone Acetaminophen (DRUG).
Who is sponsoring clinical trial NCT03823534?
This trial is sponsored by St. Louis University, which has 107 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03823534 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03823534's enrollment target sits among peer trials
60 228th of 438 higher than 205 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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