Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Insulin Resistance: early-phase trial registry
32 of 122 indexed Insulin Resistance trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #100 of 28,707 conditions by registered trial count.
122 US clinical trials · 32 currently recruiting · #100 of 28,707 conditions by registered trial count
Insulin Resistance: 122 US clinical trials tracked, 32 recruiting.
Insulin Resistance is the subject of 122 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 7 of these trials.
Enrollment posture brief
Registry condition insulin-resistance
OPEN 32 | RECR 26% | LATE 10 | EARLY 22 | RANK #100 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Attention Deficit Hyperactivity Disorder (ADHD) (26% recruiting · 19 trials)
Insulin Resistance lists 32 open slots (26% of 122 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Insulin Resistance on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Insulin Resistance is recruiting below its size-band peers.
32 of 122 indexed trials (26.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Insulin Resistance trials is spread across many organizations.
Washington University School of Medicine accounts for 7 of 122 trials (5.7%). 72 distinct sponsors appear on at least one study for this condition label.
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Most Insulin Resistance trials plan to enrol fewer than 100 people.
Median target enrolment is 53 among the 121 trials that report a genuine target (sentinel values excluded). 92 of those (76%) plan for fewer than 100 participants.
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Insulin Resistance research is mostly interventional.
102 interventional and 20 observational studies make up this index (83.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
122 total, page 2 of 3
Probiotics and Insulin Resistance in Obese Asthmatics
University of Alabama at Birmingham
NCT05949255
A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
National Center for Research Resources (NCRR)
NCT00015626
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Duke University
NCT00275145
Regional Fat Depots and Insulin Resistance
Stanford University
NCT01336777
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT05017571
Identifying Risk for Diabetes and Heart Disease in Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01809288
Financial Incentives to Exercise for Adolescents
University of Oklahoma
NCT01848353
Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00212290
Effects of Atypical Antipsychotic and Valproate Combination Therapy on Glucose and Lipid Metabolism in Schizophrenia
Washington University School of Medicine
NCT00552500
Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men
Pennington Biomedical Research Center
NCT01787617
The Health Influences of Puberty (HIP) Study
University of Colorado, Denver
NCT01775813
Effects of Omega-3 Fatty Acids on Markers of Inflammation
Stanford University
NCT01129050
The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adults
Yale University
NCT02335021
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of BFKB8488A in Otherwise Healthy Overweight and Obese Participants With Likely Insulin Resistance
Genentech
NCT02593331
Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes
Veterans Medical Research Foundation
NCT00338949
Chromium and Insulin Resistance
University of California, San Francisco
NCT00846248
A Trial of Tadalafil and Glycemic Traits
Thomas J. Wang, MD
NCT01444651
The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Fred Hutchinson Cancer Center
NCT02663544
Safety, Pharmacokinetics and Potential Activity of HE3286 in Obese Adult Subjects
Harbor Therapeutics
NCT00555451
Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery
University of Massachusetts, Worcester
NCT01007955
A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin
Daiichi Sankyo
NCT00185094
Macronutrient Effects on Alzheimer's Disease (MEAL-2)
Wake Forest University Health Sciences
NCT02463084
Progressive Weight Loss and Metabolic Health
Washington University School of Medicine
NCT01299519
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People
Mayo Clinic
NCT04158375
Insulin Resistance in Patients With Major Depression
Stanford University
NCT01106313
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
National Institute on Aging (NIA)
NCT00099697
Grains Reduce Adiposity and Improve Nutrition Study
Penn State University
NCT00924521
Timing Estrogen After MenoPaUSe
University of Colorado, Denver
NCT01605071
Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans
East Carolina University
NCT02892331
Fasting for Brain and Heart Health (FBHH)
TrueNorth Health Foundation
NCT04507516
Novel Therapy for Glucose Intolerance in HIV Disease
Stony Brook University
NCT02006914
Oral Contraceptives in the Metabolic Syndrome
Virginia Commonwealth University
NCT00205504
Metabolic Parameters 3 Months, 9 Months, and 2 Years After Bariatric Surgery
The University of Texas Health Science Center, Houston
NCT00178633
Basic Research Study to Examine the Relation Between Muscle Insulin Resistance and Lipid Production in the Liver.
Yale University
NCT02196051
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
University of Alabama at Birmingham
NCT04392284
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
Mary Ellen Vajravelu, MD
NCT05404711
Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults
University Hospitals Cleveland Medical Center
NCT01046682
Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity
Skidmore College
NCT02190136
Predictors of Response to Fenofibrate
University of Alabama at Birmingham
NCT01023750
Effects of Hepatic Ultrasound on Metabolic Homeostasis
Yale University
NCT04622683
Pioglitazone in Patients With Mood Disorders
Stanford University
NCT01559857
12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
Pusan National University
NCT04014686
Effects of Fish Oils on Inflammation and Insulin Resistance
Philip Kern
NCT00579436
Effects of Hi-maize Resistant Starch on Insulin Sensitivity
Ingredion Incorporated
NCT01058135
Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks
University of California, Davis
NCT01165853
Mitochondrial Remodeling After Exercise
Oregon State University
NCT04103424
Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia
Foundation Research, Florida
NCT00304993
Blood Flow Responses to an Oral Glucose Tolerance Test in Type 2 Diabetes
University of Kansas Medical Center
NCT00972452
The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction
Milton S. Hershey Medical Center
NCT00284960
Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis
Brigham and Women's Hospital
NCT01132118
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 7 |
| Phase 3 | 2 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Insulin Resistance records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Insulin Resistance trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Insulin Resistance page
122 registered trials, 32 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 32 Insulin Resistance trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Washington University School of Medicine sponsors the most Insulin Resistance trials on record, review their full trial history before evaluating a specific study. See Washington University School of Medicine's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Insulin Resistance condition card totals 122 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.