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ClinicalTrials.gov 32 recruiting now official registry

Insulin Resistance clinical trials

32 of 122 indexed Insulin Resistance trials are currently recruiting.

122 US clinical trials · 32 currently recruiting

Insulin Resistance is the subject of 122 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 7 of these trials.

The research picture

Insulin Resistance has 122 registered US clinical trials, 32 of them open to new participants right now, about 26% of the total.

32
recruiting participants now
26%
of trials open to enrollment
10
in Phase 3–4 (later-stage)
7
top sponsor: Washington University School of Medicine
Phase 115Phase 27Phase 32Phase 48

Active & Recent Trials

122 total, page 3 of 3

COMPLETED NA 28 participants

Resveratrol and the Metabolic Syndrome

Rockefeller University

NCT01714102

COMPLETED 28 participants

Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity

Massachusetts General Hospital

NCT04195061

COMPLETED Phase 1 28 participants

Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study

Indiana University

NCT00871234

COMPLETED 27 participants

Mitochondrial Methylation in Type 2 Diabetes

University of Arizona

NCT04126551

COMPLETED Early Phase 1 25 participants

Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)

Pennington Biomedical Research Center

NCT02697201

COMPLETED NA 24 participants

Carnitine and Liver Mitochondria Fatty Acid Processing

Pennington Biomedical Research Center

NCT03193125

COMPLETED NA 23 participants

Insulin Resistance in Adolescents

University of Wisconsin, Madison

NCT04089332

COMPLETED NA 22 participants

Relation of Obesity With Frequency of Meals (MST 0557)

Rockefeller University

NCT00229255

COMPLETED 20 participants

Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.

University of Chicago

NCT00720889

COMPLETED NA 18 participants

Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance

Beth Israel Deaconess Medical Center

NCT00004419

COMPLETED NA 16 participants

Acute Exercise on Brain Insulin Sensitivity

Rutgers, The State University of New Jersey

NCT05853913

COMPLETED 16 participants

Production of Free Fatty Acids From Blood Triglycerides

Mayo Clinic

NCT00911482

COMPLETED NA 14 participants

Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents

Yale University

NCT01901978

COMPLETED Phase 2 14 participants

Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

Nick Giannoukakis, PhD

NCT02597101

COMPLETED NA 10 participants

Effects of Sleep Duration and Architecture on Insulin Sensitivity

University of California, San Francisco

NCT01396941

COMPLETED Early Phase 1 9 participants

Low Dose Fat-Induced Insulin Resistance

University of Pennsylvania

NCT03479671

COMPLETED Early Phase 1 9 participants

Effect of 10-day Overnight Hypoxia Treatment on Whole Body Insulin Sensitivity (SLEEP HIGH Study)

Pennington Biomedical Research Center

NCT01872533

COMPLETED NA 8 participants

Comparison of Time-Restricted Feeding Versus Grazing

Pennington Biomedical Research Center

NCT01895179

COMPLETED NA 8 participants

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

Washington University School of Medicine

NCT02706288

COMPLETED Phase 1 5 participants

A Study of the Safety, Tolerance and Assessment of HE3286 on Insulin Sensitivity and Hepatic Glucose Production

Harbor Therapeutics

NCT00991107

COMPLETED NA 4 participants

Novel Therapies for Metabolic Complications of Lipodystrophies

University of Texas Southwestern Medical Center

NCT00457938

COMPLETED Phase 4

Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome

University of Colorado, Denver

NCT00364221

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Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 7
Phase 3 2
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Insulin Resistance Trial Landscape

122 indexed Insulin Resistance studies · 32 recruiting (26%).

Phase mix: 10 late (III/IV) vs 22 early (I/II).

Top sponsor: Washington University School of Medicine (7 trials), 9 others listed. 22 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Insulin Resistance?

PlainTrial tracks 122 US clinical trials for Insulin Resistance, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Insulin Resistance?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.