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Insulin Resistance clinical trials
32 of 122 indexed Insulin Resistance trials are currently recruiting.
122 US clinical trials · 32 currently recruiting
Insulin Resistance is the subject of 122 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 7 of these trials.
The research picture
Insulin Resistance has 122 registered US clinical trials, 32 of them open to new participants right now, about 26% of the total.
- 32
- recruiting participants now
- 26%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 7
- top sponsor: Washington University School of Medicine
Active & Recent Trials
122 total, page 3 of 3
Resveratrol and the Metabolic Syndrome
Rockefeller University
NCT01714102
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
Massachusetts General Hospital
NCT04195061
Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study
Indiana University
NCT00871234
Mitochondrial Methylation in Type 2 Diabetes
University of Arizona
NCT04126551
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)
Pennington Biomedical Research Center
NCT02697201
Carnitine and Liver Mitochondria Fatty Acid Processing
Pennington Biomedical Research Center
NCT03193125
Insulin Resistance in Adolescents
University of Wisconsin, Madison
NCT04089332
Relation of Obesity With Frequency of Meals (MST 0557)
Rockefeller University
NCT00229255
Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.
University of Chicago
NCT00720889
Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance
Beth Israel Deaconess Medical Center
NCT00004419
Acute Exercise on Brain Insulin Sensitivity
Rutgers, The State University of New Jersey
NCT05853913
Production of Free Fatty Acids From Blood Triglycerides
Mayo Clinic
NCT00911482
Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents
Yale University
NCT01901978
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
Nick Giannoukakis, PhD
NCT02597101
Effects of Sleep Duration and Architecture on Insulin Sensitivity
University of California, San Francisco
NCT01396941
Low Dose Fat-Induced Insulin Resistance
University of Pennsylvania
NCT03479671
Effect of 10-day Overnight Hypoxia Treatment on Whole Body Insulin Sensitivity (SLEEP HIGH Study)
Pennington Biomedical Research Center
NCT01872533
Comparison of Time-Restricted Feeding Versus Grazing
Pennington Biomedical Research Center
NCT01895179
Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health
Washington University School of Medicine
NCT02706288
A Study of the Safety, Tolerance and Assessment of HE3286 on Insulin Sensitivity and Hepatic Glucose Production
Harbor Therapeutics
NCT00991107
Novel Therapies for Metabolic Complications of Lipodystrophies
University of Texas Southwestern Medical Center
NCT00457938
Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome
University of Colorado, Denver
NCT00364221
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 7 |
| Phase 3 | 2 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Insulin Resistance Trial Landscape
122 indexed Insulin Resistance studies · 32 recruiting (26%).
Phase mix: 10 late (III/IV) vs 22 early (I/II).
Top sponsor: Washington University School of Medicine (7 trials), 9 others listed. 22 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Insulin Resistance?
PlainTrial tracks 122 US clinical trials for Insulin Resistance, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Insulin Resistance?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.