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NCT00924521 · ClinicalTrials.gov registry record · NA
Grains Reduce Adiposity and Improve Nutrition Study
A NA study of Insulin Resistance and Metabolic Syndrome, sponsored by Penn State University.
- Completed
- Registry status
- NA
- Development phase
- 54
- Enrollment target
- 1
- Study location
NCT00924521 is a NA study of Insulin Resistance and Metabolic Syndrome that has completed, run by Penn State University. The registered enrollment target is 54 participants, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00924521, a NA study of Insulin Resistance and Metabolic Syndrome, has completed, sponsored by Penn State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
- 1
- Study location
Study Summary
Whole grain intake beneficially affects body weight, body fat and glucose metabolism, and the investigators' previous work has shown that a high whole grain intake significantly reduced body fat in the abdominal region as measured by dual energy X-ray absorptiometry (DEXA) compared to a refined grain intake. Additional research is needed with regard to the mechanisms by which whole grains may affect visceral adiposity and the adipokines, which have been associated with risk for insulin resistance and type 2 diabetes. Therefore the proposed study aims to address these issues and in addition, includes exploratory work with adipocytes in cell culture to evaluate the effects of whole grains on adipocyte function. Hypothesis: There will be a greater reduction in visceral adiposity, indicators of insulin resistance (HOMA score), improvement in inflammatory status and improvement in adipokine levels after six weeks of a weight stable period and after six weeks of weight loss in subjects consuming 6-9 servings compared to 0 servings of whole grains per day.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Whole grain diet
- DIETARY_SUPPLEMENT Refined grain
Study Locations (1)
Pennsylvania
- Penn State University - University Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2009-03 |
| Est. Completion | 2011-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00924521
The ClinicalTrials.gov registry entry for NCT00924521 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (78% lower). The listed sponsor is Penn State University, which has 219 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Insulin Resistance appearing as the primary indexed condition, and to 2 interventions - of which Whole grain diet is the first listed.
NCT00924521 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00924521 about?
NCT00924521 is a clinical study titled "Grains Reduce Adiposity and Improve Nutrition Study". Whole grain intake beneficially affects body weight, body fat and glucose metabolism, and the investigators' previous work has shown that a high whole grain intake significantly reduced body fat in the abdominal region as measured by dual energy X-ray absorptiometry (DEXA) compared to a refined grai...
What is the current status of trial NCT00924521?
This trial is currently completed. It is a NA study. The enrollment target is 54 participants. The study started on 2009-03. Estimated completion is 2011-08.
What conditions does trial NCT00924521 study?
This clinical trial studies the following conditions: Insulin Resistance, Metabolic Syndrome.
What interventions are being tested in trial NCT00924521?
The interventions under investigation include: Whole grain diet (DIETARY_SUPPLEMENT), Refined grain (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00924521?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00924521 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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