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NCT02463084 · ClinicalTrials.gov registry record · NA
Macronutrient Effects on Alzheimer's Disease (MEAL-2)
A NA study of Mild Cognitive Impairment and Insulin Resistance, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT02463084 is a NA study of Mild Cognitive Impairment and Insulin Resistance that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 60 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02463084, a NA study of Mild Cognitive Impairment and Insulin Resistance, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study compares the effects of a one-month diet high in saturated fat (SF), glycemic index (GI), and salt (Na+) to a diet low in these nutritional parameters on memory and other cognitive functions, on MRI measures of brain structure, function, and perfusion, as well as on blood and cerebrospinal fluid levels of amyloid-beta (Aβ), insulin, lipids (total cholesterol, HDL, LDL, oxidized LDL, and triglycerides), cytokines, apolipoprotein E (ApoE), apolipoprotein J, cortisol, soluble low density lipoprotein receptor-related protein (sLRP), and glucose in middle-aged adults (45-65 years of age) with normal cognition or mild cognitive impairment.
Conditions Studied
Interventions
- OTHER Low Diet
- OTHER High Diet
Study Locations (1)
North Carolina
- Wake Forest Baptist Health - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2013-03 |
| Est. Completion | 2016-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02463084
The ClinicalTrials.gov registry entry for NCT02463084 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower). The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Low Diet is the first listed.
NCT02463084 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT02463084 about?
NCT02463084 is a clinical study titled "Macronutrient Effects on Alzheimer's Disease (MEAL-2)". This study compares the effects of a one-month diet high in saturated fat (SF), glycemic index (GI), and salt (Na+) to a diet low in these nutritional parameters on memory and other cognitive functions, on MRI measures of brain structure, function, and perfusion, as well as on blood and cerebrospina...
What is the current status of trial NCT02463084?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2013-03. Estimated completion is 2016-06.
What conditions does trial NCT02463084 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Insulin Resistance, Prediabetic State, Prehypertension, Middle Age.
What interventions are being tested in trial NCT02463084?
The interventions under investigation include: Low Diet (OTHER), High Diet (OTHER).
Who is sponsoring clinical trial NCT02463084?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02463084 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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