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NCT01046682 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults
A Phase 2 study of HIV and Inflammation, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT01046682 is a Phase 2 study of HIV and Inflammation that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 40 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01046682, a Phase 2 study of HIV and Inflammation, has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a phase II, open label, randomized-controlled pilot study designed to study both the efficacy and safety of salsalate in decreasing endothelial cell dysfunction, systemic inflammation, and insulin resistance in HIV-infected adults. The investigators hypothesis is that salsalate will reduce inflammation and therefore endothelial cell activation and insulin resistance. The sample size will be 40, with an equal number of people being randomized to one of two groups. The first arm will be randomized to salsalate therapy. The second arm will act as a control group. The study duration will be 13 weeks.
Conditions Studied
Interventions
- DRUG Salsalate
Study Locations (1)
Ohio
- University Hospitals Case Medical Center - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2009-01 |
| Est. Completion | 2009-07 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01046682
The ClinicalTrials.gov registry entry for NCT01046682 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 303 other HIV trials with a reported enrollment target (91% lower). The listed sponsor is University Hospitals Cleveland Medical Center, which has 230 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with HIV appearing as the primary indexed condition, and to 1 intervention - of which Salsalate is the first listed.
NCT01046682 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT01046682 about?
NCT01046682 is a clinical study titled "Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults". This is a phase II, open label, randomized-controlled pilot study designed to study both the efficacy and safety of salsalate in decreasing endothelial cell dysfunction, systemic inflammation, and insulin resistance in HIV-infected adults. The investigators hypothesis is that salsalate will reduce i...
What is the current status of trial NCT01046682?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2009-01. Estimated completion is 2009-07.
What conditions does trial NCT01046682 study?
This clinical trial studies the following conditions: HIV, Inflammation, Insulin Resistance, Endothelial Dysfunction.
What interventions are being tested in trial NCT01046682?
The interventions under investigation include: Salsalate (DRUG).
Who is sponsoring clinical trial NCT01046682?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01046682 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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