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NCT04158375 · ClinicalTrials.gov registry record · NA
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People
A NA study of Obesity and Insulin Resistance, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 58
- Enrollment target
- 3
- Study locations
NCT04158375: Completed NA study of Obesity and Insulin Resistance, sponsored by Mayo Clinic.
NCT04158375 is a NA study of Obesity and Insulin Resistance that has completed, run by Mayo Clinic. The registered enrollment target is 58 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04158375, a NA study of Obesity and Insulin Resistance, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 58 participants
- Enrollment target
- 3
- Study locations
Study Summary
This proposal will investigate the underlying mechanisms of enhanced insulin sensitivity and improvement of muscle loss and performance in insulin resistant people by resistance exercise training. Based on the investigator's preliminary data, they hypothesize that the key regulators of health benefits of resistance training are two genes: PGC-1a4 and PPARB;, and that the increased expression of these genes following resistance training facilitates storage of glucose in muscle and enhances its utilization for the energy need of muscle for contraction as well as enhancing muscle mass and performance. The investigators will also determine whether resistance training can reduce the higher oxidative stress in insulin resistant humans and improve their muscle protein quality.
Conditions Studied
Interventions
- BEHAVIORAL Resistance Exercise
Study Locations (3)
Arizona
- Mayo Clinic in Arizona - Scottsdale
Florida
- Mayo Clinic in Florida - Jacksonville
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2020-09-02 |
| Est. Completion | 2024-09-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04158375
The ClinicalTrials.gov registry entry for NCT04158375 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Resistance Exercise is the first listed.
NCT04158375 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Arizona, Florida, Minnesota.
Frequently Asked Questions
What is clinical trial NCT04158375 about?
NCT04158375 is a clinical study titled "Molecular Mechanisms of Exercise Benefits to Insulin Resistant People". This proposal will investigate the underlying mechanisms of enhanced insulin sensitivity and improvement of muscle loss and performance in insulin resistant people by resistance exercise training. Based on the investigator's preliminary data, they hypothesize that the key regulators of health benefi...
What is the current status of trial NCT04158375?
This trial is currently completed. It is a NA study. The enrollment target is 58 participants. The study started on 2020-09-02. Estimated completion is 2024-09-30.
What conditions does trial NCT04158375 study?
This clinical trial studies the following conditions: Obesity, Insulin Resistance.
What interventions are being tested in trial NCT04158375?
The interventions under investigation include: Resistance Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT04158375?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04158375 being conducted?
This trial has 3 study locations across Arizona, Florida, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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