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ClinicalTrials.gov 4 recruiting now official registry

Attention Deficit Hyperactivity Disorder (ADHD) clinical trials

4 of 16 indexed Attention Deficit Hyperactivity Disorder (ADHD) trials are currently recruiting.

16 US clinical trials · 4 currently recruiting

Attention Deficit Hyperactivity Disorder (ADHD) is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Shire, running 3 of these trials.

The research picture

Attention Deficit Hyperactivity Disorder (ADHD) has 16 registered US clinical trials, 4 of them open to new participants right now, about 25% of the total.

4
recruiting participants now
25%
of trials open to enrollment
8
in Phase 3–4 (later-stage)
3
top sponsor: Shire
Phase 11Phase 35Phase 43

Active & Recent Trials

16 total, page 1 of 1

RECRUITING NA 204 participants

Improving ADHD Teen Driving - Virtual Reality

Children's Hospital Medical Center, Cincinnati

NCT06960980

RECRUITING NA 200 participants

Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT06810180

RECRUITING Phase 4 196 participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Gagan Joshi

NCT06853665

RECRUITING NA 24 participants

L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD

Texas Tech University Health Sciences Center

NCT07189442

COMPLETED Phase 3 333 participants

Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 1)

Supernus Pharmaceuticals

NCT02618408

COMPLETED Phase 4 318 participants

Dose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesylate) in Children Aged 6-12 Diagnosed With ADHD

Shire

NCT00500071

COMPLETED Phase 3 275 participants

Safety and Efficacy Study of SHP465 in Adults Aged 18-55 Years With Attention-deficit/ Hyperactivity Disorder (ADHD)

Shire

NCT02604407

COMPLETED Phase 3 264 participants

Safety and Efficacy Study of SHP465 in Children and Adolescents Aged 6-17 Years With Attention-Deficit Hyperactivity Disorder (ADHD)

Shire

NCT02466425

COMPLETED NA 106 participants

Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)

Weill Medical College of Cornell University

NCT02574273

COMPLETED Phase 3 95 participants

A Study to Evaluate the Efficacy and Safety of Dasotraline in Children 6 to 12 Years Old With Attention-Deficit Hyperactivity Disorder (ADHD) in a Simulated Classroom Setting.

Sumitomo Pharma America

NCT03231800

COMPLETED Phase 3 60 participants

PRC-063 in an ADULT Workplace Environment

Rhodes Pharmaceuticals, L.P.

NCT02225639

COMPLETED NA 35 participants

Organizational Skill Training (OST) in Schools

NYU Langone Health

NCT02663986

COMPLETED 33 participants

Measuring Adherence to Medication for Depression and Attention-deficit Hyperactivity Disorder

Wake Forest University Health Sciences

NCT01430767

COMPLETED Phase 1 30 participants

Phase I Single Dose, Open-Label Pharmacokinetic Study and Single-Blind, Placebo-Controlled Dose Escalation Study of NFC-1 in Adolescents With Attention-Deficit Hyperactivity Disorder

Aevi Genomic Medicine, LLC, a Cerecor company

NCT02286817

COMPLETED Phase 4 24 participants

Cardiovascular Study of Lisdexamfetamine in Healthy and Hypertensive Attention Deficit Hyperactivity Disorder Adults

Massachusetts General Hospital

NCT00753012

COMPLETED NA 18 participants

12 Month Open Extension of TNS for ADHD.

James McGough

NCT03888391

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 5
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Attention Deficit Hyperactivity Disorder (ADHD) Trial Landscape

16 indexed Attention Deficit Hyperactivity Disorder (ADHD) studies · 4 recruiting (25%).

Phase mix: 8 late (III/IV) vs 1 early (I/II).

Top sponsor: Shire (3 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Attention Deficit Hyperactivity Disorder (ADHD)?

PlainTrial tracks 16 US clinical trials for Attention Deficit Hyperactivity Disorder (ADHD), of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Attention Deficit Hyperactivity Disorder (ADHD)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.