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COMPLETED Phase 4

Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes

NCT00212290 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to examine the effects of treating insulin resistance on memory and attention, brain glucose utilization, and proteins in spinal fluid.

Interventions

  • DRUG placebo
  • DRUG pioglitazone
  • DRUG nateglinide

Study Locations (2)

Washington

  • VA Puget Sound Health Care System (Seattle Campus) — Seattle
  • VA Puget Sound Health Care System (American Lake Campus) — Tacoma

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2002-11
Est. Completion 2006-12
Phase Phase 4

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00212290

The ClinicalTrials.gov registry entry for NCT00212290 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Type 2 Diabetes Mellitus appearing as the primary indexed condition, and to 3 interventions — of which placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00212290 reports 2 study locations spanning 1 distinct geographic area — top geographies include Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00212290 about?

NCT00212290 is a clinical study titled "Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes". The purpose of this study is to examine the effects of treating insulin resistance on memory and attention, brain glucose utilization, and proteins in spinal fluid.

What is the current status of trial NCT00212290?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 140 participants. The study started on 2002-11. Estimated completion is 2006-12.

What conditions does trial NCT00212290 study?

This clinical trial studies the following conditions: Type 2 Diabetes Mellitus, Insulin Resistance. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00212290?

The interventions under investigation include: placebo (DRUG), pioglitazone (DRUG), nateglinide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00212290?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00212290 being conducted?

This trial has 2 study locations across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial