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ClinicalTrials.gov 51 recruiting now official registry

Inflammation clinical trials

51 of 133 indexed Inflammation trials are currently recruiting.

133 US clinical trials · 51 currently recruiting

Inflammation is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 6 of these trials.

The research picture

Inflammation has 133 registered US clinical trials, 51 of them open to new participants right now, about 38% of the total.

51
recruiting participants now
38%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
6
top sponsor: Massachusetts General Hospital
Phase 110Phase 216Phase 38Phase 45

Active & Recent Trials

133 total, page 1 of 3

RECRUITING Phase 3 6,150 participants

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

Population Health Research Institute

NCT04774159

RECRUITING 4,200 participants

Biomarkers in Infection

Beth Israel Deaconess Medical Center

NCT02545478

RECRUITING 2,000 participants

Natural History of the Human Biological Response to Environmental Exposure and Injury

National Institute of Environmental Health Sciences (NIEHS)

NCT04888923

RECRUITING 750 participants

Immune Cell Response to Stimuli

National Institute of Environmental Health Sciences (NIEHS)

NCT00397280

RECRUITING NA 450 participants

Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)

New York State Psychiatric Institute

NCT05477901

RECRUITING 400 participants

Diagnosis and Management of Inflammatory and Infectious Diseases

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00557726

RECRUITING 400 participants

Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

MaineHealth

NCT02664831

RECRUITING NA 342 participants

Improving Maternal Sleep and Mental Health

University of Colorado, Colorado Springs

NCT06544941

RECRUITING NA 300 participants

The Impact of a Race-Based Stress Reduction Intervention

Loyola University

NCT05902741

RECRUITING NA 276 participants

Wellness App for Sleep Disturbance in Hematological Cancer Patients

The University of Texas Health Science Center at San Antonio

NCT05294991

RECRUITING NA 260 participants

Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention

University of Maryland, Baltimore

NCT06002685

RECRUITING Phase 2 240 participants

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

Abcentra

NCT06927739

RECRUITING NA 240 participants

UCLA REST Study (REsearch on Sleep Techniques)

University of California, Los Angeles

NCT05576090

RECRUITING Phase 2 225 participants

Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1

University of Pennsylvania

NCT04480554

RECRUITING NA 220 participants

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

Wake Forest University Health Sciences

NCT04810858

RECRUITING NA 220 participants

Synbiotic to Attenuate Resorption of the Skeleton

Hebrew SeniorLife

NCT06389539

RECRUITING Phase 2 216 participants

Modulating Exercise Dosage to Improve Concussion Recovery

University of Colorado, Denver

NCT05434130

RECRUITING NA 180 participants

Reducing Metabolic Dysregulation in Dyads

University of South Carolina

NCT06117241

RECRUITING NA 180 participants

Stress Phenotypes and Preterm Birth

Columbia University

NCT05229666

RECRUITING NA 150 participants

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

Florida International University

NCT05136703

RECRUITING NA 120 participants

Gut Microbiota-dependent Health Impacts of Haskap Berries

Montana State University

NCT06546020

RECRUITING Phase 2 118 participants

Reducing Frailty for Older Cancer Survivors Using Supplements II

University of Rochester

NCT06068543

RECRUITING 117 participants

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Washington University School of Medicine

NCT05277558

RECRUITING NA 100 participants

Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD

Texas Tech University

NCT06055322

RECRUITING 100 participants

Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV

University of Pittsburgh

NCT05502653

RECRUITING Phase 2 100 participants

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Massachusetts General Hospital

NCT06136546

RECRUITING Phase 1 90 participants

Novel Approaches for Improving Vascular Function in Veterans With HFpEF

VA Office of Research and Development

NCT06312748

RECRUITING 80 participants

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Brigham and Women's Hospital

NCT07222683

RECRUITING NA 75 participants

Cognitive Remediation

Cutter Lindbergh

NCT07171450

RECRUITING NA 70 participants

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

Nathaniel Jenkins

NCT06454344

RECRUITING Phase 2 64 participants

Passive Stretching in Peripheral Arterial Disease Patients

University of Wisconsin, La Crosse

NCT06420752

RECRUITING Phase 2 60 participants

Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

University of Texas Southwestern Medical Center

NCT06130059

RECRUITING NA 50 participants

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Alexander T. Yahanda

NCT07218133

RECRUITING NA 46 participants

The Impact of Biophoton Therapy on Self-Grown Stem Cells

First Institute of All Medicines

NCT06855459

RECRUITING Phase 2 40 participants

Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer

University of Rochester

NCT06295588

RECRUITING NA 40 participants

Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women

University of California, Davis

NCT06544954

RECRUITING NA 36 participants

The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease

Massachusetts General Hospital

NCT04505865

RECRUITING 34 participants

Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

University of Minnesota

NCT02437396

RECRUITING Phase 4 32 participants

Skin Barrier Function and Inflammation in Aging: The BIA Study

University of California, San Francisco

NCT06750653

RECRUITING NA 30 participants

Ketone Ester And Salt (KEAS) in Older Adults

Indiana University

NCT06868719

RECRUITING NA 30 participants

Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.

University of Texas at Austin

NCT07361861

RECRUITING NA 30 participants

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

University of Maryland, Baltimore

NCT03201094

RECRUITING NA 30 participants

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

Massachusetts General Hospital

NCT04496947

RECRUITING NA 30 participants

Impact of Haskap Berries on Recovery From High Intensity Resistance Training

Montana State University

NCT07344727

RECRUITING NA 30 participants

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Georgia State University

NCT06735651

RECRUITING NA 28 participants

Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults

University of Connecticut

NCT07079982

RECRUITING NA 25 participants

Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents

University of California, Davis

NCT07125001

RECRUITING Early Phase 1 24 participants

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

University of Iowa

NCT06489249

RECRUITING NA 20 participants

Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

University of California, Davis

NCT05236374

RECRUITING 13 participants

Regulation of Inflammatory Genes in Psoriasis

University of Alabama at Birmingham

NCT03125655

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 16
Phase 3 8
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Inflammation Trial Landscape

133 indexed Inflammation studies · 51 recruiting (38%).

Phase mix: 13 late (III/IV) vs 26 early (I/II).

Top sponsor: Massachusetts General Hospital (6 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Inflammation?

PlainTrial tracks 133 US clinical trials for Inflammation, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Inflammation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.