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Inflammation: early-phase trial registry
51 of 133 indexed Inflammation trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #86 of 28,707 conditions by registered trial count.
133 US clinical trials · 51 currently recruiting · #86 of 28,707 conditions by registered trial count
Inflammation: 133 US clinical trials tracked, 51 recruiting.
Inflammation is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 6 of these trials.
Enrollment posture brief
Registry condition inflammation
OPEN 51 | RECR 38% | LATE 13 | EARLY 26 | RANK #86 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Adolescent Behavior (38% recruiting · 47 trials)
Inflammation lists 51 open slots (38% of 133 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Inflammation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Inflammation recruits in line with its size-band peers.
51 of 133 indexed trials (38.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Inflammation trials is spread across many organizations.
Massachusetts General Hospital accounts for 6 of 133 trials (4.5%). 95 distinct sponsors appear on at least one study for this condition label.
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Most Inflammation trials plan to enrol fewer than 100 people.
Median target enrolment is 64 among the 133 trials that report a genuine target (sentinel values excluded). 85 of those (63.9%) plan for fewer than 100 participants.
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Inflammation research is mostly interventional.
107 interventional and 26 observational studies make up this index (80.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
133 total, page 2 of 3
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
Quan Dong Nguyen
NCT06161415
ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
Novo Nordisk A/S
NCT05021835
Maternal & Offspring Microbiome Study
Stanford University
NCT05123612
IGNITE Firefighters' Health
Stanford University
NCT06567561
Almonds to Improve Gut Health and Decrease Inflammation
Oregon State University
NCT05790564
Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
Massachusetts General Hospital
NCT05774665
Sleep and Inflammatory Resolution Pathway
Beth Israel Deaconess Medical Center
NCT03377543
Understanding Dose Related Effects of Strawberry
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06173765
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
Ohio State University
NCT05318183
The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes
Loma Linda University
NCT06159543
Cardiovascular Structure and Function in the Mucopolysaccharidoses
Children's Hospital of Orange County
NCT05063435
Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study
Anne B. Newman
NCT05727384
Plant-based Diet for Kidney Transplant Recipients
George Washington University
NCT06186843
Salt-Sensitivity and Immunity Cell Activation
Vanderbilt University Medical Center
NCT03753204
Induction of Gut Permeability by an Oral Vaccine
USDA, Western Human Nutrition Research Center
NCT04083950
Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19
University of Michigan
NCT04706533
Inflammation and Nutritional Parameters in Hemodialysis Patients Using Reprocessed Dialyzers
Fresenius Medical Care North America
NCT00440908
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
National Institute on Aging (NIA)
NCT00183001
Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
Bausch & Lomb Incorporated
NCT01060072
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Bausch & Lomb Incorporated
NCT01591161
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
Xigen
NCT02235272
Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic
New York Botanical Garden
NCT00109980
Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00776412
The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot Study
University of Florida
NCT02676466
The Effect of a Nutritional Supplement Product Containing Cactus Fruit Juice (Nopalea) on C-Reactive Protein
Mark Mattie
NCT01881178
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
Allergan
NCT00524264
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
National Institute of Environmental Health Sciences (NIEHS)
NCT01143519
Salivary Inflammatory Biomarkers: Predictors & Comparative Effects of Sonicare/Elite-Flexcare in Stages of Perio Disease
University of North Carolina, Chapel Hill
NCT02187185
Vaccine Efficacy in Diabetic and Elderly Patients
Tulane University
NCT02675608
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT05017571
Effect of Anatabine on Elevated Blood Levels of C-reactive Protein
Roskamp Institute
NCT01607619
Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis
University of Florida
NCT00361283
Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes
Massachusetts General Hospital
NCT03818581
Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD
NYU Langone Health
NCT02135939
Vitamin D Repletion in Coronary Artery Disease
Seth I. Sokol, M.D.
NCT01570309
Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers
Duke University
NCT01343810
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
University of Colorado, Denver
NCT04998006
The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Fred Hutchinson Cancer Center
NCT02663544
Effect of a Spice Blend on Cardiovascular Risk Factors and Diet Satisfaction
Penn State University
NCT03064932
Tart Cherry Supplementation & Gut Microbiome and Inflammation
Ohio University
NCT04467372
Analysis of Microalbuminuria and Markers of Inflammation and Oxidative Stress in Adolescents of Different Ethnic Backgrounds
University of California, Davis
NCT00616707
Effect of High-Legume Diet on Colorectal Cancer Risk
National Cancer Institute (NCI)
NCT00339469
A Study Evaluating the Association of Inflammation With Hemodialysis Access Type
Montefiore Medical Center
NCT01011985
Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Older Men and Postmenopausal Women: A Randomized Controlled Study
Loma Linda University
NCT05031663
Study on Immunopathogenesis in HIV and Hepatitis C Coinfection
Rush University Medical Center
NCT01296529
Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract
Mati Therapeutics
NCT03496467
Antiplatelet Therapy in HIV
NYU Langone Health
NCT02559414
Zinc Supplementation and Cardiovascular Risk in HIV
Grace McComsey
NCT02856269
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
Big Bold Health, PBC
NCT05234203
Bioequivalency Study of Meloxicam Tablets Under Fed Conditions
Roxane Laboratories
NCT00601887
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 16 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on Inflammation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Inflammation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Inflammation page
133 registered trials, 51 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 51 Inflammation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Massachusetts General Hospital sponsors the most Inflammation trials on record, review their full trial history before evaluating a specific study. See Massachusetts General Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Inflammation condition card totals 133 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.