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NCT06927739 · ClinicalTrials.gov registry record · Phase 2
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
A Phase 2 study of Inflammation and Heart Disease, sponsored by Abcentra.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 240
- Enrollment target
- 20
- Study locations
NCT06927739 is a Phase 2 study of Inflammation and Heart Disease that is actively recruiting participants, run by Abcentra. The registered enrollment target is 240 participants, below the 286-participant average among 132 other Inflammation trials with a reported enrollment target (16% lower). The trial reports 20 study locations across 17 states.
The verdict
NCT06927739, a Phase 2 study of Inflammation and Heart Disease, is actively recruiting participants, sponsored by Abcentra.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 240 participants
- Enrollment target
- 20
- Study locations
Study Summary
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Orticumab
Study Locations (20)
Central Hungary
- Abcentra Investigational Site - Budapest
- Abcentra Investigational Site - Budapest
- Abcentra Investigational Site - Budapest
California
- Abcentra Investigational Site - Los Angeles
- Abcentra Investigational Site - Torrance
Florida
- Abcentra Investigational Site - Boca Raton
Indiana
- Abcentra Investigational Site - Richmond
Kentucky
- Abcentra Investigational Site - Louisville
Maryland
- Abcentra Investigational Site - Baltimore
Michigan
- Abcentra Investigational Site - Midland
Moravian-Silesian Region
- Abcentra Investigational Site - Ostrava
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2025-08-11 |
| Est. Completion | 2027-06-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06927739
The ClinicalTrials.gov registry entry for NCT06927739 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 286-participant average among 132 other Inflammation trials with a reported enrollment target (16% lower). The listed sponsor is Abcentra, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Inflammation appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06927739 reports 20 study locations spanning 17 distinct geographic areas - top geographies include Central Hungary, California, Florida.
Frequently Asked Questions
What is clinical trial NCT06927739 about?
NCT06927739 is a clinical study titled "Focused Orticumab Research for Treating Inflammation in Coronary Arteries". The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on...
What is the current status of trial NCT06927739?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2025-08-11. Estimated completion is 2027-06-01.
What conditions does trial NCT06927739 study?
This clinical trial studies the following conditions: Inflammation, Heart Disease, Coronary Arterial Disease (CAD), Acute Coronary Syndromes, Myocardial Infarct.
What interventions are being tested in trial NCT06927739?
The interventions under investigation include: Placebo (DRUG), Orticumab (DRUG).
Who is sponsoring clinical trial NCT06927739?
This trial is sponsored by Abcentra, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06927739 being conducted?
This trial has 20 study locations across California, Florida, Indiana, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.