Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

NCT06927739 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies

Interventions

  • DRUG Placebo
  • DRUG Orticumab

Study Locations (20)

Central Hungary

  • Abcentra Investigational Site — Budapest
  • Abcentra Investigational Site — Budapest
  • Abcentra Investigational Site — Budapest

California

  • Abcentra Investigational Site — Los Angeles
  • Abcentra Investigational Site — Torrance

Florida

  • Abcentra Investigational Site — Boca Raton

Indiana

  • Abcentra Investigational Site — Richmond

Kentucky

  • Abcentra Investigational Site — Louisville

Maryland

  • Abcentra Investigational Site — Baltimore

Michigan

  • Abcentra Investigational Site — Midland

Moravian-Silesian Region

  • Abcentra Investigational Site — Ostrava

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2025-08-11
Est. Completion 2027-06-01
Phase Phase 2

Sponsor

Abcentra

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06927739

The ClinicalTrials.gov registry entry for NCT06927739 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abcentra, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Inflammation appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06927739 reports 20 study locations spanning 17 distinct geographic areas — top geographies include Central Hungary, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06927739 about?

NCT06927739 is a clinical study titled "Focused Orticumab Research for Treating Inflammation in Coronary Arteries". The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on...

What is the current status of trial NCT06927739?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2025-08-11. Estimated completion is 2027-06-01.

What conditions does trial NCT06927739 study?

This clinical trial studies the following conditions: Inflammation, Heart Disease, Coronary Arterial Disease (CAD), Acute Coronary Syndromes, Myocardial Infarct. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06927739?

The interventions under investigation include: Placebo (DRUG), Orticumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06927739?

This trial is sponsored by Abcentra, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06927739 being conducted?

This trial has 20 study locations across California, Florida, Indiana, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial