Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05229666 · ClinicalTrials.gov registry record · NA
Stress Phenotypes and Preterm Birth
A NA study of Stress and Inflammation, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT05229666: Recruiting NA study of Stress and Inflammation, sponsored by Columbia University.
NCT05229666 is a NA study of Stress and Inflammation that is actively recruiting participants, run by Columbia University. The registered enrollment target is 180 participants, below the 785-participant average among 152 other Stress trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05229666, a NA study of Stress and Inflammation, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
Pregnancy ends in preterm birth (PTB) for approximately 1 in 10 women, though more often for Non-Hispanic Black women, 14.12% PTB rate, compared to 9.09% for Non-Hispanic White women. Psychosocial stress and childhood trauma each are associated with risk for PTB and PTB has an intergenerational impact: mothers born preterm are more likely to give birth pretern, especially amongst Black women. In this project, we will study mitochondria, which contain their own genome, the mitochondria DNA, and are inherited from the mother, as they represent a potential intersection point between psychosocial experiences and their biological embedding in underlying disease outcomes such as PTB
Primary Outcome
The high stress group is calculated using various measures including multiple psychosocial, life course, biological variables, and acute stress reactivity to a cognitive challenge (Stroop test).
Conditions Studied
Interventions
- OTHER Cognitive Challenge
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2021-12-09 |
| Est. Completion | 2027-11 |
| Phase | NA |
What NCT05229666 shows while recruiting
NCT05229666 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 152 other Stress trials with a reported enrollment target (77% lower).
The record links to 4 conditions, with Stress appearing as the primary indexed condition, and to 1 intervention - of which Cognitive Challenge is the first listed.
NCT05229666 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05229666 about?
NCT05229666 is a clinical study titled "Stress Phenotypes and Preterm Birth". Pregnancy ends in preterm birth (PTB) for approximately 1 in 10 women, though more often for Non-Hispanic Black women, 14.12% PTB rate, compared to 9.09% for Non-Hispanic White women. Psychosocial stress and childhood trauma each are associated with risk for PTB and PTB has an intergenerational impa...
What is the current status of trial NCT05229666?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2021-12-09. Estimated completion is 2027-11.
What conditions does trial NCT05229666 study?
This clinical trial studies the following conditions: Stress, Inflammation, Mental Health Issue, Preterm Birth.
What interventions are being tested in trial NCT05229666?
The interventions under investigation include: Cognitive Challenge (OTHER).
Who is sponsoring clinical trial NCT05229666?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05229666 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05229666's enrollment target sits among peer trials
180 32nd of 152 higher than 121 of 152 other Stress trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Mindfulness-Based Intervention With a Supplement for Stress-Related Problems in College Students Across Multiple Sites (4SITE)
RECRUITING · NA
-
Digital Intervention for Physical Activity
RECRUITING · NA
-
Cocooned Moms Study
RECRUITING · NA
-
Student Exercise and Sleep Timing Study - Part 2
RECRUITING · NA
-
Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease
RECRUITING · NA
-
ACT for HIV-Positive Men
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01558804 · 180 participants
GRoup A StrePtococcus
- NCT02932176 · 180 participants
Machine Learning for Handheld Vascular Studies
- NCT03384563 · 180 participants · Phase 4
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
- NCT03423628 · 180 participants · Phase 1
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI