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NCT05902741 · ClinicalTrials.gov registry record · NA

The Impact of a Race-Based Stress Reduction Intervention

A NA study of Stress and Inflammation, sponsored by Loyola University.

Recruiting
Registry status
NA
Development phase
300
Enrollment target
1
Study location

NCT05902741: Recruiting NA study of Stress and Inflammation, sponsored by Loyola University.

NCT05902741 is a NA study of Stress and Inflammation that is actively recruiting participants, run by Loyola University. The registered enrollment target is 300 participants, below the 784-participant average among 152 other Stress trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05902741, a NA study of Stress and Inflammation, is actively recruiting participants, sponsored by Loyola University.

RECRUITING
Registry status
NA
Development phase
300 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment. Participants will placed in one of the two following groups: * The RiSE program will focus on teaching participants how to reduce their stress levels and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks. * The Health Education program will include education on how to improve general health and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks. Participants will provide saliva to measure cytokines and DNA methylation (DNAm), complete questionnaires, and have blood pressure, heart rate, and weight measured at the following clinic visits: 1. Prior to starting the intervention 2. Mid-way through the intervention (Week 4) 3. End of the intervention (Week 8) 4. Six (6) months after the completion of the intervention

Primary Outcome

Perceived Stress Scale (PSS-10). Scores range from 0 to 40 with higher score suggesting worse outcome.

Interventions

  • BEHAVIORAL RiSE
  • BEHAVIORAL HEP

Study Locations (1)

Illinois

  • Loyola University Chicago - Maywood

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-10-18
Est. Completion 2028-01-31
Phase NA
Loyola University

92 total trials

What NCT05902741 shows while recruiting

NCT05902741 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 784-participant average among 152 other Stress trials with a reported enrollment target (62% lower).

The record links to 3 conditions, with Stress appearing as the primary indexed condition, and to 2 interventions - of which RiSE is the first listed.

NCT05902741 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05902741 about?

NCT05902741 is a clinical study titled "The Impact of a Race-Based Stress Reduction Intervention". The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answe...

What is the current status of trial NCT05902741?

This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2023-10-18. Estimated completion is 2028-01-31.

What conditions does trial NCT05902741 study?

This clinical trial studies the following conditions: Stress, Inflammation, Racism.

What interventions are being tested in trial NCT05902741?

The interventions under investigation include: RiSE (BEHAVIORAL), HEP (BEHAVIORAL).

Who is sponsoring clinical trial NCT05902741?

This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05902741 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stress

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05902741's enrollment target sits among peer trials

300 19th of 152 higher than 132 of 152 other Stress trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05902741, the US trial registry maintained by the National Library of Medicine. NCT05902741 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.