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NCT05477901 · ClinicalTrials.gov registry record · NA
Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)
A NA study of Inflammation and Family Relations, sponsored by New York State Psychiatric Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 450
- Enrollment target
- 2
- Study locations
NCT05477901: Recruiting NA study of Inflammation and Family Relations, sponsored by New York State Psychiatric Institute.
NCT05477901 is a NA study of Inflammation and Family Relations that is actively recruiting participants, run by New York State Psychiatric Institute. The registered enrollment target is 450 participants, above the 285-participant average among 132 other Inflammation trials with a reported enrollment target (58% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05477901, a NA study of Inflammation and Family Relations, is actively recruiting participants, sponsored by New York State Psychiatric Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 450 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study examines the impact of Auxilio Brasil (AB), a cash transfer program to mothers of school-age children, on resource-deprived populations in Brazil and its protective effects on child neurodevelopment and mental health. The investigators will conduct a randomized clinical trial (RCT) among those already receiving AB in which 300 families will be randomized in a 1:1 ratio to receive either a high ($40/month) or low ($2/month) supplemental transfer for 2 years. Three hundred children (index child participants; 7-10 years old) will be enrolled across both study arms. Additionally, up to 150 siblings ("sibling participants;" 7-10 years old) will be enrolled. Eligible families who decide to participate will sign a study-specific informed consent (mother) and assent (child) form. The UNIFESP team will conduct the respective assessments at baseline, approximately 8- and 16- months, 24-months and approximately 6-months post-RCT. Aim 1: Determine the impact of high vs low cash transfers on children's exposure to adversities (ACEs) and neurodevelopment. Aim 2: Determine the impact of cash transfers on children's inflammatory markers and HPA activity/cortisol. Exploratory Aim: The investigators will explore (i) whether sex/gender of the children moderates the pathways in the above mediation model; and (ii) whether cash transfer-related effects persist 6 months post-RCT.
Primary Outcome
Family History Epidemiologic screener is a 9-item (+subitems) checklist to asses child's ACEs, more checked items mean more ACEs.
Conditions Studied
Interventions
- OTHER Supplemental cash transfer
Study Locations (2)
New York
- New York State Psychiatric Institute - New York
São Paulo
- UNIFESP - São Paulo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 450 participants |
| Start Date | 2025-05-17 |
| Est. Completion | 2028-01-01 |
| Phase | NA |
What NCT05477901 shows while recruiting
NCT05477901 is an interventional study that assigns participants to a tested intervention. The registered 450 participants enrollment target is mid-sized for trials with a published cap, above the 285-participant average among 132 other Inflammation trials with a reported enrollment target (58% higher).
The record links to 4 conditions, with Inflammation appearing as the primary indexed condition, and to 1 intervention - of which Supplemental cash transfer is the first listed.
NCT05477901 reports a single indexed study location in New York, São Paulo.
Frequently Asked Questions
What is clinical trial NCT05477901 about?
NCT05477901 is a clinical study titled "Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)". This study examines the impact of Auxilio Brasil (AB), a cash transfer program to mothers of school-age children, on resource-deprived populations in Brazil and its protective effects on child neurodevelopment and mental health. The investigators will conduct a randomized clinical trial (RCT) among ...
What is the current status of trial NCT05477901?
This trial is currently recruiting. It is a NA study. The enrollment target is 450 participants. The study started on 2025-05-17. Estimated completion is 2028-01-01.
What conditions does trial NCT05477901 study?
This clinical trial studies the following conditions: Inflammation, Family Relations, HPA, CBCL.
What interventions are being tested in trial NCT05477901?
The interventions under investigation include: Supplemental cash transfer (OTHER).
Who is sponsoring clinical trial NCT05477901?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05477901 being conducted?
This trial has 2 study locations across New York, São Paulo. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05477901's enrollment target sits among peer trials
450 9th of 132 higher than 124 of 132 other Inflammation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Inflammation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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