Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Physical Activity

Open-data reference.

132 US clinical trials · 45 currently recruiting

Active & Recent Trials

RECRUITING NA 8,000 participants

A Comprehensive Trauma-sensitive Approach to Physical Activity Promotion in Schools (CSPAP-T)

Seattle Children's Hospital

NCT05382975

RECRUITING 1,000 participants

Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study

Aura

NCT06664944

RECRUITING NA 900 participants

Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial

Texas A&M University

NCT07079995

RECRUITING NA 500 participants

Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

Texas A&M University

NCT05867433

RECRUITING NA 450 participants

Co-Creating Active Middle School Communities to Increase Student Physical Activity

Deanna Hoelscher

NCT06970067

RECRUITING NA 432 participants

A Multi-level Mother-daughter Physical Activity Intervention for Pre- Adolescent Latinas

San Diego State University

NCT07088406

RECRUITING NA 406 participants

Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas

University of Texas, El Paso

NCT06411769

RECRUITING NA 400 participants

Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)

AdventHealth Translational Research Institute

NCT04334343

RECRUITING NA 400 participants

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

Massachusetts General Hospital

NCT06246929

RECRUITING NA 360 participants

Together Everyone Achieves More (TEAM) Trial

University of South Carolina

NCT05519696

RECRUITING NA 324 participants

PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes

University of Utah

NCT06690788

RECRUITING NA 300 participants

Survivors Uniting for Remote Guided Exercise

Colorado State University

NCT07290309

RECRUITING NA 300 participants

Mobile Supportive Teams for Reinforcing Increased Daily Exercise Study

University of South Carolina

NCT06662292

RECRUITING NA 260 participants

Making Healthy Habits Stick

University of Tennessee

NCT06745180

RECRUITING NA 257 participants

The Fit With Us Study

University of Alabama at Birmingham

NCT06207084

RECRUITING NA 242 participants

Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men

University of Colorado, Denver

NCT06912984

RECRUITING NA 240 participants

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06848491

RECRUITING Phase 2 240 participants

Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

Arizona State University

NCT06337708

RECRUITING Phase 2 210 participants

Effectiveness of Exercise After an ICD

University of Washington

NCT03544489

RECRUITING NA 200 participants

Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT06810180

RECRUITING NA 200 participants

Postnatal Exercise to Activate Baby's Brown Fat

Joslin Diabetes Center

NCT07467694

RECRUITING NA 160 participants

Effects of Personalized Exercise Prescriptions Through Mobile Health on Physical Activity and Health Outcomes in the Cancer Survivors

The University of Tennessee, Knoxville

NCT06840028

RECRUITING NA 150 participants

Gerofit and Cognition

VA Office of Research and Development

NCT06107842

RECRUITING NA 144 participants

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

Arizona State University

NCT05980052

RECRUITING 120 participants

eMOTION: Examining Implicit Attitudes in Physical Activity Engagement

University of Southern California

NCT07044570

RECRUITING NA 96 participants

Physical Activity Targeting Metabolic Syndrome for Prevention of Breast Cancer in SAI Women

Rush University Medical Center

NCT06827704

RECRUITING NA 80 participants

A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

University of Kansas Medical Center

NCT06667661

RECRUITING NA 80 participants

Data Coaching Process to Address Staff Physical Activity Promoting Behavior and Child Physical Activity

Kansas State University

NCT07195409

RECRUITING NA 80 participants

Inspiring Seniors Towards Exercise Promotion to Protect Cognition

Emory University

NCT06496425

RECRUITING NA 70 participants

Promoting Physical Activity and Healthy Eating in Latinas

Brown University

NCT06979297

RECRUITING 66 participants

Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation

M.D. Anderson Cancer Center

NCT07140770

RECRUITING NA 60 participants

Va Meh Du: A Sports-based Mental Health Promotion Intervention for Karenni Refugees

University of North Carolina, Greensboro

NCT06921499

RECRUITING Phase 2 60 participants

Promoting Active Therapy: Path to Wellness

Kansas State University

NCT06858189

RECRUITING NA 60 participants

OTAGO Exercise Program and Motivational Interviewing

Oregon Health and Science University

NCT06931067

RECRUITING 54 participants

Measuring Outcomes With Validated Exercise

Boston University

NCT07270185

RECRUITING NA 53 participants

Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students

University of Alabama, Tuscaloo

NCT07415460

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 48 participants

StandUPTV Habits: Feasibility Trial for Maintaining Reductions in Sedentary Screen Time

Arizona State University

NCT06700525

RECRUITING NA 46 participants

Using a mHealth Intervention to Promote Physical Activity in Phase III Cardiac Rehabilitation Clients

AdventHealth University

NCT05795036

RECRUITING NA 40 participants

Exploring Virtual Reality Adventure Training Exergaming

The University of Texas at Arlington

NCT05563805

RECRUITING NA 40 participants

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

Massachusetts General Hospital

NCT07102797

RECRUITING NA 36 participants

Time to Move in Pregnancy Hyperglycemia

The University of Tennessee, Knoxville

NCT06125704

RECRUITING NA 30 participants

Physical Activity: Feasibility Study

Binghamton University

NCT05935111

RECRUITING NA 20 participants

Teen Mom Study Feasibility Trial

University of Mississippi Medical Center

NCT05843903

RECRUITING NA 20 participants

Latinas Integrating Fitness and Therapy

Colorado State University

NCT07223346

ACTIVE NOT RECRUITING NA 1,000 participants

Intern Health Study 2024

University of Michigan

NCT06465680

ACTIVE NOT RECRUITING NA 554 participants

Childhood Obesity Treatment Designed for Low Income and Hispanic Families

University of Colorado, Denver

NCT05041855

ACTIVE NOT RECRUITING 479 participants

TROLLEY Study - TRansit Opportunities for HeaLth, Livability, Exercise and EquitY

University of California, San Diego

NCT04940481

ACTIVE NOT RECRUITING NA 432 participants

Mentoring to be Active for Rural Appalachia Children

Ohio State University

NCT05758441

ACTIVE NOT RECRUITING 312 participants

Measuring Outcomes of Activity in Intensive Care

Vanderbilt University Medical Center

NCT03115840

ACTIVE NOT RECRUITING NA 260 participants

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

Massachusetts General Hospital

NCT05373745

ACTIVE NOT RECRUITING NA 210 participants

The Sleep2BWell Trial

Columbia University

NCT06565104

ACTIVE NOT RECRUITING NA 200 participants

Lupus Intervention for Fatigue Trial

Northwestern University

NCT02653287

ACTIVE NOT RECRUITING NA 187 participants

Efficacy Trial Healthy Dads, Healthy Kids for Hispanic Fathers and Children

Baylor College of Medicine

NCT05334420

ACTIVE NOT RECRUITING NA 120 participants

Healthy Activities Improve Lives (HAIL)

Massachusetts General Hospital

NCT06267547

ACTIVE NOT RECRUITING NA 100 participants

Multi-site Animal Assisted Intervention for Children With DD and Their Family Dog

Oregon State University

NCT04799119

ACTIVE NOT RECRUITING Phase 3 50 participants

Randomized Controlled Physical Activity App Intervention for Black Women

Stony Brook University

NCT07114900

ACTIVE NOT RECRUITING NA 48 participants

PA Moves Trial - PCP Participants

University of Pittsburgh

NCT05319821

COMPLETED Phase 1 7,192 participants

Cooking for Health Optimization With Patients

Tulane University

NCT03443635

COMPLETED NA 2,562 participants

Intern Health Study 2022 and 2023

University of Michigan

NCT05436145

COMPLETED Phase 1 1,422 participants

The Active by Choice Today (ACT) Trial to Increase Physical Activity

University of South Carolina

NCT01028144

COMPLETED NA 1,250 participants

Evaluation of the BOKS Before-school Physical Activity Program

Massachusetts General Hospital

NCT03190135

COMPLETED NA 1,241 participants

Promoting Physical Activity in Rural Communities

Washington University School of Medicine

NCT03683173

COMPLETED NA 950 participants

Evaluation of the "Americans in Motion - Healthy Interventions" Project

American Academy of Family Physicians

NCT00534482

COMPLETED NA 925 participants

Linking Churches With Parks to Increase Physical Activity Among Latinos

RAND

NCT03858868

COMPLETED NA 838 participants

Evaluation of a Walking School Bus Program

Seattle Children's Hospital

NCT01626807

COMPLETED NA 779 participants

STEP Together: An Effectiveness-Implementation Study of Social Incentives and Physical Activity

Abramson Cancer Center at Penn Medicine

NCT04942535

COMPLETED Phase 2 600 participants

Promoting Healthy Lifestyles Among Firefighters

Oregon Health and Science University

NCT00006181

COMPLETED NA 578 participants

Healthy Mothers-Healthy Children Nutrition

University of Miami

NCT03866902

COMPLETED NA 556 participants

Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)

University of Utah

NCT02470156

COMPLETED NA 476 participants

Peer Empowerment Program for Physical Activity in Low Income and Minority Seniors

University of California, San Diego

NCT02405325

COMPLETED NA 450 participants

Physical Activity Incentives

Stanford University

NCT03037658

COMPLETED NA 400 participants

Improving Health Behaviors Through Telephone Linked Care

American Academy of Family Physicians

NCT00314197

COMPLETED NA 325 participants

Communication Intervention Physical Activity

University of Rochester

NCT01419093

COMPLETED NA 323 participants

Physical Activity Promotion for Breast and Endometrial Cancer Survivors

University of Wisconsin, Madison

NCT04262180

COMPLETED NA 309 participants

Community-based Intervention Effects on Older Adults' Physical Activity

University of Minnesota

NCT03326141

COMPLETED NA 308 participants

WalkLink: Internet-based Walking Program

Milton S. Hershey Medical Center

NCT01142804

COMPLETED NA 307 participants

Multilevel Intervention for Physical Activity in Retirement Communities

University of California, San Diego

NCT01155011

COMPLETED NA 301 participants

Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women

Rush University Medical Center

NCT03558828

COMPLETED NA 280 participants

The Okla Achokma Project

University of Southern Mississippi

NCT06633939

COMPLETED NA 245 participants

Testing Scalable, IVR-supported Cancer Prevention Interventions in the Rural Alabama Black Belt

University of Alabama at Birmingham

NCT03903874

COMPLETED NA 201 participants

Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers

Seattle Children's Hospital

NCT03575884

COMPLETED NA 180 participants

Social and Financial Incentives to Increase Physical Activity Among Overweight and Obese Veterans

VA Office of Research and Development

NCT03563027

COMPLETED NA 174 participants

Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial

University of New Mexi

NCT03726476

COMPLETED NA 155 participants

Study Investigating Role of Unalike Patient Positioning on PROMIS Scores

University of Louisville

NCT03446950

COMPLETED NA 149 participants

Schedule Intervention to Increase Sustainable Walking Activity in Midlife Working Adults

Brandeis University

NCT03272438

COMPLETED 126 participants

Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome

Cornell University

NCT01859663

COMPLETED NA 110 participants

StandUPTV: Reducing Sedentary Screen Time in Adults

Arizona State University

NCT04464993

COMPLETED NA 96 participants

Mindfulness-Based College: Stage 1

Brown University

NCT03124446

COMPLETED NA 88 participants

Exercise Genes: Genomic Association With Exercise Reinforcement

USDA Grand Forks Human Nutrition Research Center

NCT02416882

COMPLETED NA 85 participants

The FAITH! Trial: A mHealth Intervention to Improve Cardiovascular Health Among African-Americans

Mayo Clinic

NCT03777709

COMPLETED NA 83 participants

Home-based, Individually-tailored Physical Activity Print Intervention for African American Women in the Deep South

University of Alabama at Birmingham

NCT02574689

COMPLETED NA 78 participants

Caminamos: A Smartphone App for Latinas to Connect With Walking Partners

Klein Buendel

NCT03854916

COMPLETED NA 73 participants

Evaluation of the Personal Activity Intelligence (PAI) Score

Ohio University

NCT04309513

COMPLETED NA 72 participants

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT05887401

COMPLETED NA 72 participants

Improving Neuropathy and Mobility in People With Early Diabetes

VA Office of Research and Development

NCT00780559

COMPLETED NA 64 participants

CalFitness Smartphone-Delivered Physical Activity Intervention

University of California, Berkeley

NCT02886871

COMPLETED 64 participants

Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents

Children's Mercy Hospital Kansas City

NCT03157063

COMPLETED NA 64 participants

Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults

George Mason University

NCT04281654

COMPLETED NA 63 participants

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06171945

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Physical Activity Trial Landscape

ClinicalTrials.gov lists 132 US studies indexed under Physical Activity, and 45 of those are currently open to recruitment — roughly 34% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Physical Activity shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Physical Activity is led by Arizona State University with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Physical Activity?

PlainTrial tracks 132 US clinical trials for Physical Activity, of which 45 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Physical Activity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →