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Inflammation
Open-data reference.
133 US clinical trials · 51 currently recruiting
Active & Recent Trials
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Population Health Research Institute
NCT04774159
Biomarkers in Infection
Beth Israel Deaconess Medical Center
NCT02545478
Natural History of the Human Biological Response to Environmental Exposure and Injury
National Institute of Environmental Health Sciences (NIEHS)
NCT04888923
Immune Cell Response to Stimuli
National Institute of Environmental Health Sciences (NIEHS)
NCT00397280
Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)
New York State Psychiatric Institute
NCT05477901
Diagnosis and Management of Inflammatory and Infectious Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00557726
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
MaineHealth
NCT02664831
Improving Maternal Sleep and Mental Health
University of Colorado, Colorado Springs
NCT06544941
The Impact of a Race-Based Stress Reduction Intervention
Loyola University
NCT05902741
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention
University of Maryland, Baltimore
NCT06002685
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
Abcentra
NCT06927739
UCLA REST Study (REsearch on Sleep Techniques)
University of California, Los Angeles
NCT05576090
Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
University of Pennsylvania
NCT04480554
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Wake Forest University Health Sciences
NCT04810858
Synbiotic to Attenuate Resorption of the Skeleton
Hebrew SeniorLife
NCT06389539
Modulating Exercise Dosage to Improve Concussion Recovery
University of Colorado, Denver
NCT05434130
Reducing Metabolic Dysregulation in Dyads
University of South Carolina
NCT06117241
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
Florida International University
NCT05136703
Gut Microbiota-dependent Health Impacts of Haskap Berries
Montana State University
NCT06546020
Reducing Frailty for Older Cancer Survivors Using Supplements II
University of Rochester
NCT06068543
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Washington University School of Medicine
NCT05277558
Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD
Texas Tech University
NCT06055322
Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
University of Pittsburgh
NCT05502653
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
Massachusetts General Hospital
NCT06136546
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
VA Office of Research and Development
NCT06312748
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
Brigham and Women's Hospital
NCT07222683
Cognitive Remediation
Cutter Lindbergh
NCT07171450
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
Passive Stretching in Peripheral Arterial Disease Patients
University of Wisconsin, La Crosse
NCT06420752
Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
University of Texas Southwestern Medical Center
NCT06130059
Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
Alexander T. Yahanda
NCT07218133
The Impact of Biophoton Therapy on Self-Grown Stem Cells
First Institute of All Medicines
NCT06855459
Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer
University of Rochester
NCT06295588
Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women
University of California, Davis
NCT06544954
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease
Massachusetts General Hospital
NCT04505865
Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease
University of Minnesota
NCT02437396
Skin Barrier Function and Inflammation in Aging: The BIA Study
University of California, San Francis
NCT06750653
Ketone Ester And Salt (KEAS) in Older Adults
Indiana University
NCT06868719
Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.
University of Texas at Austin
NCT07361861
Impact of NMES and HPRO on Recovery After SAH- Pilot Study
University of Maryland, Baltimore
NCT03201094
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Massachusetts General Hospital
NCT04496947
Impact of Haskap Berries on Recovery From High Intensity Resistance Training
Montana State University
NCT07344727
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
Georgia State University
NCT06735651
Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults
University of Connecticut
NCT07079982
Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents
University of California, Davis
NCT07125001
Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use
University of Iowa
NCT06489249
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
University of California, Davis
NCT05236374
Regulation of Inflammatory Genes in Psoriasis
University of Alabama at Birmingham
NCT03125655
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
Quan Dong Nguyen
NCT06161415
ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
Novo Nordisk A/S
NCT05021835
Maternal & Offspring Microbiome Study
Stanford University
NCT05123612
IGNITE Firefighters' Health
Stanford University
NCT06567561
Almonds to Improve Gut Health and Decrease Inflammation
Oregon State University
NCT05790564
Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
Massachusetts General Hospital
NCT05774665
Sleep and Inflammatory Resolution Pathway
Beth Israel Deaconess Medical Center
NCT03377543
Understanding Dose Related Effects of Strawberry
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06173765
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
Ohio State University
NCT05318183
The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes
Loma Linda University
NCT06159543
Cardiovascular Structure and Function in the Mucopolysaccharidoses
Children's Hospital of Orange County
NCT05063435
Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study
Anne B. Newman
NCT05727384
Plant-based Diet for Kidney Transplant Recipients
George Washington University
NCT06186843
Salt-Sensitivity and Immunity Cell Activation
Vanderbilt University Medical Center
NCT03753204
Induction of Gut Permeability by an Oral Vaccine
USDA, Western Human Nutrition Research Center
NCT04083950
Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19
University of Michigan
NCT04706533
Inflammation and Nutritional Parameters in Hemodialysis Patients Using Reprocessed Dialyzers
Fresenius Medical Care North America
NCT00440908
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
National Institute on Aging (NIA)
NCT00183001
Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
Bausch & Lomb Incorporated
NCT01060072
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Bausch & Lomb Incorporated
NCT01591161
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
Xigen
NCT02235272
Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic
New York Botanical Garden
NCT00109980
Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00776412
The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot Study
University of Florida
NCT02676466
The Effect of a Nutritional Supplement Product Containing Cactus Fruit Juice (Nopalea) on C-Reactive Protein
Mark Mattie
NCT01881178
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
Allergan
NCT00524264
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
National Institute of Environmental Health Sciences (NIEHS)
NCT01143519
Salivary Inflammatory Biomarkers: Predictors & Comparative Effects of Sonicare/Elite-Flexcare in Stages of Perio Disease
University of North Carolina, Chapel Hill
NCT02187185
Vaccine Efficacy in Diabetic and Elderly Patients
Tulane University
NCT02675608
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT05017571
Effect of Anatabine on Elevated Blood Levels of C-reactive Protein
Roskamp Institute
NCT01607619
Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis
University of Florida
NCT00361283
Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes
Massachusetts General Hospital
NCT03818581
Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD
NYU Langone Health
NCT02135939
Vitamin D Repletion in Coronary Artery Disease
Seth I. Sokol, M.D.
NCT01570309
Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers
Duke University
NCT01343810
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
University of Colorado, Denver
NCT04998006
The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Fred Hutchinson Cancer Center
NCT02663544
Effect of a Spice Blend on Cardiovascular Risk Factors and Diet Satisfaction
Penn State University
NCT03064932
Tart Cherry Supplementation & Gut Microbiome and Inflammation
Ohio University
NCT04467372
Analysis of Microalbuminuria and Markers of Inflammation and Oxidative Stress in Adolescents of Different Ethnic Backgrounds
University of California, Davis
NCT00616707
Effect of High-Legume Diet on Colorectal Cancer Risk
National Cancer Institute (NCI)
NCT00339469
A Study Evaluating the Association of Inflammation With Hemodialysis Access Type
Montefiore Medical Center
NCT01011985
Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Older Men and Postmenopausal Women: A Randomized Controlled Study
Loma Linda University
NCT05031663
Study on Immunopathogenesis in HIV and Hepatitis C Coinfection
Rush University Medical Center
NCT01296529
Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract
Mati Therapeutics
NCT03496467
Antiplatelet Therapy in HIV
NYU Langone Health
NCT02559414
Zinc Supplementation and Cardiovascular Risk in HIV
Grace McComsey
NCT02856269
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
Big Bold Health, PBC
NCT05234203
Bioequivalency Study of Meloxicam Tablets Under Fed Conditions
Roxane Laboratories
NCT00601887
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 10 |
| Phase 2 | 16 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Inflammation Trial Landscape
ClinicalTrials.gov lists 133 US studies indexed under Inflammation, and 51 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Inflammation shows 13 late-stage studies (Phase 3 and Phase 4 combined) alongside 26 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Inflammation is led by Massachusetts General Hospital with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Inflammation?
PlainTrial tracks 133 US clinical trials for Inflammation, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Inflammation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.