Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Inflammation: early-phase trial registry
51 of 133 indexed Inflammation trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #86 of 28,707 conditions by registered trial count.
133 US clinical trials · 51 currently recruiting · #86 of 28,707 conditions by registered trial count
Inflammation: 133 US clinical trials tracked, 51 recruiting.
Inflammation is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 6 of these trials.
Enrollment posture brief
Registry condition inflammation
OPEN 51 | RECR 38% | LATE 13 | EARLY 26 | RANK #86 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Adolescent Behavior (38% recruiting · 47 trials)
Inflammation lists 51 open slots (38% of 133 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Inflammation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Inflammation recruits in line with its size-band peers.
51 of 133 indexed trials (38.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Inflammation trials is spread across many organizations.
Massachusetts General Hospital accounts for 6 of 133 trials (4.5%). 95 distinct sponsors appear on at least one study for this condition label.
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Most Inflammation trials plan to enrol fewer than 100 people.
Median target enrolment is 64 among the 133 trials that report a genuine target (sentinel values excluded). 85 of those (63.9%) plan for fewer than 100 participants.
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Inflammation research is mostly interventional.
107 interventional and 26 observational studies make up this index (80.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
133 total, page 1 of 3
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Population Health Research Institute
NCT04774159
Biomarkers in Infection
Beth Israel Deaconess Medical Center
NCT02545478
Natural History of the Human Biological Response to Environmental Exposure and Injury
National Institute of Environmental Health Sciences (NIEHS)
NCT04888923
Immune Cell Response to Stimuli
National Institute of Environmental Health Sciences (NIEHS)
NCT00397280
Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)
New York State Psychiatric Institute
NCT05477901
Diagnosis and Management of Inflammatory and Infectious Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00557726
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
MaineHealth
NCT02664831
Improving Maternal Sleep and Mental Health
University of Colorado, Colorado Springs
NCT06544941
The Impact of a Race-Based Stress Reduction Intervention
Loyola University
NCT05902741
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention
University of Maryland, Baltimore
NCT06002685
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
Abcentra
NCT06927739
UCLA REST Study (REsearch on Sleep Techniques)
University of California, Los Angeles
NCT05576090
Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
University of Pennsylvania
NCT04480554
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Wake Forest University Health Sciences
NCT04810858
Synbiotic to Attenuate Resorption of the Skeleton
Hebrew SeniorLife
NCT06389539
Modulating Exercise Dosage to Improve Concussion Recovery
University of Colorado, Denver
NCT05434130
Reducing Metabolic Dysregulation in Dyads
University of South Carolina
NCT06117241
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
Florida International University
NCT05136703
Gut Microbiota-dependent Health Impacts of Haskap Berries
Montana State University
NCT06546020
Reducing Frailty for Older Cancer Survivors Using Supplements II
University of Rochester
NCT06068543
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Washington University School of Medicine
NCT05277558
Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD
Texas Tech University
NCT06055322
Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
University of Pittsburgh
NCT05502653
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
Massachusetts General Hospital
NCT06136546
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
VA Office of Research and Development
NCT06312748
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
Brigham and Women's Hospital
NCT07222683
Cognitive Remediation
Cutter Lindbergh
NCT07171450
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
Passive Stretching in Peripheral Arterial Disease Patients
University of Wisconsin, La Crosse
NCT06420752
Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
University of Texas Southwestern Medical Center
NCT06130059
Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
Alexander T. Yahanda
NCT07218133
The Impact of Biophoton Therapy on Self-Grown Stem Cells
First Institute of All Medicines
NCT06855459
Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer
University of Rochester
NCT06295588
Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women
University of California, Davis
NCT06544954
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease
Massachusetts General Hospital
NCT04505865
Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease
University of Minnesota
NCT02437396
Skin Barrier Function and Inflammation in Aging: The BIA Study
University of California, San Francisco
NCT06750653
Ketone Ester And Salt (KEAS) in Older Adults
Indiana University
NCT06868719
Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.
University of Texas at Austin
NCT07361861
Impact of NMES and HPRO on Recovery After SAH- Pilot Study
University of Maryland, Baltimore
NCT03201094
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Massachusetts General Hospital
NCT04496947
Impact of Haskap Berries on Recovery From High Intensity Resistance Training
Montana State University
NCT07344727
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
Georgia State University
NCT06735651
Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults
University of Connecticut
NCT07079982
Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents
University of California, Davis
NCT07125001
Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use
University of Iowa
NCT06489249
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
University of California, Davis
NCT05236374
Regulation of Inflammatory Genes in Psoriasis
University of Alabama at Birmingham
NCT03125655
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 16 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on Inflammation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Inflammation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Inflammation page
133 registered trials, 51 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 51 Inflammation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Massachusetts General Hospital sponsors the most Inflammation trials on record, review their full trial history before evaluating a specific study. See Massachusetts General Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Inflammation condition card totals 133 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.