Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hypertension: full-pipeline trial registry
152 of 472 indexed Hypertension trials are currently recruiting.
Corpus placement: #8 of 28,707 conditions by registered trial count.
472 US clinical trials · 152 currently recruiting · #8 of 28,707 conditions by registered trial count
Hypertension: 472 US clinical trials tracked, 152 recruiting.
Hypertension is the subject of 472 registered US clinical trials on ClinicalTrials.gov, 152 of them currently open to new participants. 65 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 15 of these trials.
Enrollment posture brief
Registry condition hypertension
OPEN 152 | RECR 32% | LATE 65 | EARLY 64 | RANK #8 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Leukemia, Myeloid, Acute (32% recruiting · 31 trials)
Hypertension lists 152 open slots (32% of 472 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypertension is recruiting below its size-band peers.
152 of 472 indexed trials (32.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypertension trials is spread across many organizations.
Johns Hopkins University accounts for 15 of 472 trials (3.2%). 195 distinct sponsors appear on at least one study for this condition label.
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Typical Hypertension enrolment sits around 168 participants.
Median target enrolment is 168 among the 471 trials that report a genuine target (sentinel values excluded). 170 of those (36.1%) plan for fewer than 100 participants.
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Hypertension research is mostly interventional.
407 interventional and 65 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
472 total, page 2 of 10
HOPE-BP 2.0: Evaluating the Optimal Duration of Postpartum Remote Blood Pressure Monitoring
University of Minnesota
NCT07204756
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients
Novartis Pharmaceuticals
NCT06857955
Project 2: ACHIEVE- HF
Henry Ford Health System
NCT05330221
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
Church-based Intervention to Improve Blood Pressure in African Americans
Rush University Medical Center
NCT05220332
Jackson Heart Study Women's Hypertension Study
NYU Langone Health
NCT06511479
Partners in Control, Phase II: Using Remote Monitoring Technology With Community Health Workers to Support Hypertension Management for Latinx Patients
NYU Langone Health
NCT06730230
Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure
University of Alabama at Birmingham
NCT06962488
Gut Microbiota in Metabolic Surgery
Vanderbilt University Medical Center
NCT05000996
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie
NCT06559891
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
University of California, San Diego
NCT07398391
Sisters of Heart (Hermanas de Corazón): A Community Health Worker Initiative for Improving Heart Health in Migrant Farmworker Women
Emory University
NCT07111026
Study of Disrupted Sleep in Somali Americans
Mayo Clinic
NCT05411029
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
NCT07090161
WEAVE NM: Heart Health and Nutrition for Life
University of New Mexi
NCT07074145
Arterial Stiffness and Blood Pressure
VA Office of Research and Development
NCT06495710
A Study of LY3971297 in Healthy Participants
Eli Lilly and Company
NCT06148272
RCT of Sensor-controlled Digital Game for Hypertension Self-care in a Native American Community
University of Texas at Austin
NCT05671406
Team Lifestyle Immersion Hypertension Control Project
Meharry Medical College
NCT07201948
My Interprofessional Care Team for Adherence and Research Engagement Disparities
University of Arizona
NCT05470439
PILI 'Āina Household
University of Hawaii
NCT06526273
OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
Case Western Reserve University
NCT05293756
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
Kennesaw State University
NCT07221279
Technology-enabled Management Versus Usual Care for Blood Pressure
Stanford University
NCT05479461
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
Indiana University
NCT05856591
E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control
Rush University Medical Center
NCT06899750
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
University of Chicago
NCT06397456
Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)
Rong Zhang
NCT05331144
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
University of Minnesota
NCT04439370
Effect of Electro-Acupuncture on Blood Pressure
University of California, Irvine
NCT00932139
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Zona Health
NCT06843577
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
University of Alabama at Birmingham
NCT04971720
Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions
University of Pittsburgh
NCT06605807
Groceries for Residents of Southeastern USA to Stop Hypertension
Beth Israel Deaconess Medical Center
NCT06891911
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
Duke University
NCT05129345
Impact GLP-1 Agonists Following Bariatric
University of Missouri-Columbia
NCT06132477
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
International Consortium of Circulatory Assist Clinicians
NCT06039176
Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)
Ablative Solutions
NCT07083765
MIND Foods and Aerobic Training in Black Adults With HTN
Indiana University
NCT06152614
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Wake Forest University Health Sciences
NCT04752293
VicorderCS NIBP Validation Study to Review The Ability to Capture Blood Pressure Measurements
80 Beats Medical
NCT06560034
Dietary Intervention to Improve Kidney Transplant Outcomes
University of California, Davis
NCT05449496
Healthy Living Anson Study
University of North Carolina, Chapel Hill
NCT07126587
Interactive Computer-adaptive Chronic Kidney Disease Education Program
University of Chicago
NCT06364358
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Douglas Seals
NCT03821623
Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
Northwestern University
NCT06466161
Inspiratory Muscle Strength Training in Chronic Kidney Disease
University of Colorado, Denver
NCT04911491
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
University of Arizona
NCT06307574
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 25 |
| Phase 3 | 37 |
| Phase 4 | 28 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertension page
472 registered trials, 152 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 152 Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Hypertension trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertension condition card totals 472 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.