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NCT07090161 · ClinicalTrials.gov registry record · Phase 2

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

A Phase 2 study of Hypertension and Uncontrolled Hypertension, sponsored by Vanda Pharmaceuticals.

Recruiting
Registry status
Phase 2
Development phase
240
Enrollment target
20
Study locations

NCT07090161: Recruiting Phase 2 study of Hypertension and Uncontrolled Hypertension, sponsored by Vanda Pharmaceuticals.

NCT07090161 is a Phase 2 study of Hypertension and Uncontrolled Hypertension that is actively recruiting participants, run by Vanda Pharmaceuticals. The registered enrollment target is 240 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (93% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07090161, a Phase 2 study of Hypertension and Uncontrolled Hypertension, is actively recruiting participants, sponsored by Vanda Pharmaceuticals.

RECRUITING
Registry status
Phase 2
Development phase
240 participants
Enrollment target
20
Study locations

Study Summary

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

Interventions

  • DRUG Placebo
  • DRUG iloperidone

Study Locations (20)

California

  • Vanda Investigative Site - Chula Vista
  • Vanda Investigative Site - Dublin
  • Vanda Investigative Site - Valencia
  • Vanda Investigative Site - Walnut Creek

Arizona

  • Vanda Investigative Site - Phoenix
  • Vanda Investigative Site - Tempe
  • Vanda Investigative Site - Tucson

Florida

  • Vanda Investigative Site - Doral
  • Vanda Investigative Site - Fort Myers

Illinois

  • Vanda Investigative Site - Oak Brook
  • Vanda Investigative Site - Tinley Park

Kansas

  • Vanda Investigative Site - El Dorado
  • Vanda Investigative Site - Wichita

New York

  • Vanda Investigative Site - Mount Kisco
  • Vanda Investigative Site - Rochester

Georgia

  • Vanda Investigative Site - Columbus

Kentucky

  • Vanda Investigative Site - Lexington

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2025-09-15
Est. Completion 2026-11
Phase Phase 2
Vanda Pharmaceuticals

68 total trials

What NCT07090161 shows while recruiting

NCT07090161 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (93% lower).

The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07090161 names 20 study sites across 11 states, led by California, Arizona, Florida.

Frequently Asked Questions

What is clinical trial NCT07090161 about?

NCT07090161 is a clinical study titled "Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension". A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

What is the current status of trial NCT07090161?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2025-09-15. Estimated completion is 2026-11.

What conditions does trial NCT07090161 study?

This clinical trial studies the following conditions: Hypertension, Uncontrolled Hypertension.

What interventions are being tested in trial NCT07090161?

The interventions under investigation include: Placebo (DRUG), iloperidone (DRUG).

Who is sponsoring clinical trial NCT07090161?

This trial is sponsored by Vanda Pharmaceuticals, which has 68 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07090161 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hypertension

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07090161's enrollment target sits among peer trials

240 198th of 470 higher than 271 of 470 other Hypertension trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT07090161, the US trial registry maintained by the National Library of Medicine. NCT07090161 (mid enrollment · wide site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.