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Cardiovascular Diseases clinical trials
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
304 US clinical trials · 134 currently recruiting
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
The research picture
Cardiovascular Diseases has 304 registered US clinical trials, 134 of them open to new participants right now, about 44% of the total.
- 134
- recruiting participants now
- 44%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Duke University
Active & Recent Trials
304 total, page 5 of 7
IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.
Tufts Medical Center
NCT00091507
A Trial of CS-747 (Prasugrel) Compared With Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention (PCI)
Eli Lilly and Company
NCT00059215
Understanding the Impact of Neighborhood Type on Physical Activity in Older Adults
Stanford University
NCT00094211
Clinician Counseling and Cultural Competency to Improve Hypertension Control and Therapy Adherence
Boston Medical Center
NCT00201149
ISCHEMIA-Chronic Kidney Disease Trial
NYU Langone Health
NCT01985360
CV Disease in Adolescents With Type 2 Diabetes
Children's Hospital Medical Center, Cincinnati
NCT00114998
Assessing the Effectiveness of Concurrent Peer Review for Patients With Cardiovascular Disease and Diabetes
University of Rochester
NCT00508014
Heart Rate Variability and Sudden Cardiac Death
Columbia University
NCT00005235
Physician Uncertainty Reduction for Hypertension
Baylor College of Medicine
NCT00201084
Comparison of Two Methods to Diagnose Coronary Artery Disease
Johns Hopkins University
NCT00063531
Solutions for Atrial Fibrillation Edvocacy (SAFE)
American Pharmacists Association Foundation
NCT05067114
Reducing Disparities in Primary Prevention of Cardiovascular Disease
Northwestern University
NCT01610609
Promoting Healthy Lifestyles Among Firefighters
Oregon Health and Science University
NCT00006181
Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
CardioDx
NCT01117506
Targeting of UnControlled Hypertension in Emergency Department
University of Illinois at Chicago
NCT03749499
LEAVE Safe With DOACs
University of Massachusetts, Worcester
NCT04068727
HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms
Edwards Lifesciences
NCT05009589
Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention
University of Pennsylvania
NCT02508116
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal
Windber Research Institute
NCT01805492
Behavioral and Recovery Support for 30 Day Post-Discharge Care
Laguna Health
NCT05431894
Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise
Iowa State University
NCT03069092
Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial
CardioDx
NCT00583297
Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery
Duke University
NCT00041392
Reducing Risk Factors in Peripheral Arterial Disease
Northwestern University
NCT00217919
Impact of SomaSignal Tests on the Choice of Glucose-lowering Medications
University of Colorado, Denver
NCT05166382
pRESET for Occlusive Stroke Treatment
phenox
NCT03994822
Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
University of Washington
NCT00880178
Estrogen, HDL, and Coronary Heart Disease in Women
Tufts University
NCT00083824
Evaluating the Effectiveness of a Computerized Medication Adherence System at Reducing Cardiovascular Disease Risk Factors
PHCC
NCT00796172
School-Based Intervention to Increase Physical Activity Among Adolescent Females
National Heart, Lung, and Blood Institute (NHLBI)
NCT00296101
Predictive Medicine Research. (PRE MED)
Emory University
NCT00336570
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Duke University
NCT00275145
Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System
Cordis US
NCT01355406
Veterans Walk for Health Study
US Department of Veterans Affairs
NCT00123435
Pharmacist-led Group Medical Visits to Help With Diabetes Management
VA Office of Research and Development
NCT00554671
Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation
Baylor Research Institute
NCT00224809
Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase
Duke University
NCT06278883
Virtual AppLication-supported ENvironment To INcrease Exercise During Cardiac Rehabilitation Study
University of Michigan
NCT04587882
Healthy Lifestyle Behavior Intervention for Latino Women
University of California, Los Angeles
NCT01333241
Epidemiology of Hypertensive Emergency
Columbia University
NCT00005240
Diabetes Remote Intervention to improVe Use of Evidence-based Medications
Brigham and Women's Hospital
NCT06046560
Heartmatters Challenge - First Responders
Boston Heart Diagnostics
NCT03322046
Comparing TR Band to Statseal in Conjunction With TR Band
VA Long Beach Healthcare System
NCT03028025
Sapphire 3 CTO Study
OrbusNeich
NCT06358508
Strong People Strength Training Study
Cornell University
NCT04203563
Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
University of Miami
NCT00253682
Worksite Wellness Within Long-term Care Facilities
University of Maryland, Baltimore
NCT04166643
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Black Hills Center for American Indian Health
NCT00608387
Comparison of Hematocrit Levels in Infant Heart Surgery
National Heart, Lung, and Blood Institute (NHLBI)
NCT00006183
Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk
National Heart, Lung, and Blood Institute (NHLBI)
NCT00613158
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiovascular Diseases Trial Landscape
304 indexed Cardiovascular Diseases studies · 134 recruiting (44%).
Phase mix: 26 late (III/IV) vs 28 early (I/II).
Top sponsor: Duke University (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiovascular Diseases?
PlainTrial tracks 304 US clinical trials for Cardiovascular Diseases, of which 134 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiovascular Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.