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ClinicalTrials.gov 134 recruiting now full pipeline #27 of 28,707 conditions

Cardiovascular Diseases: full-pipeline trial registry

134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.

Corpus placement: #27 of 28,707 conditions by registered trial count.

304 US clinical trials · 134 currently recruiting · #27 of 28,707 conditions by registered trial count

Cardiovascular Diseases: 304 US clinical trials tracked, 134 recruiting.

Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.

Enrollment posture brief

Registry condition cardiovascular-diseases

OPEN 134 | RECR 44% | LATE 26 | EARLY 28 | RANK #27 | SPON 10

Nearest open-share peer: Suicide (44% recruiting · 93 trials)

Acute Myeloid Leukemia51.8%Chronic Pain46%Cardiovascular Diseases (thi…44%HIV35.9%COVID-1922.7%
Open-enrollment share among volume-matched conditions near Cardiovascular Diseases

Cardiovascular Diseases lists 134 open slots (44% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiovascular Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiovascular Diseases is recruiting above its size-band peers.

    134 of 304 indexed trials (44.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cardiovascular Diseases trials is spread across many organizations.

    Duke University accounts for 10 of 304 trials (3.3%). 159 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiovascular Diseases enrolment sits around 200 participants.

    Median target enrolment is 200 among the 301 trials that report a genuine target (sentinel values excluded). 101 of those (33.6%) plan for fewer than 100 participants.

  4. Cardiovascular Diseases research is mostly interventional.

    225 interventional and 79 observational studies make up this index (74% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 218Phase 313Phase 413

Open and recent trials

304 total, page 6 of 7

COMPLETED Phase 3 118 participants

Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)

University of California, San Francisco

NCT03207945

COMPLETED NA 116 participants

Best Rest: Rest Time Before Blood Pressure Measurement Trial

Johns Hopkins University

NCT04031768

COMPLETED 110 participants

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

Thomas Jefferson University

NCT03646370

COMPLETED NA 108 participants

Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults

Korea Ginseng Corporation

NCT06236243

COMPLETED NA 101 participants

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

Gabi SmartCare

NCT05319236

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED 100 participants

Mil Familias-Santa Barbara's Operational Pilot to Understand Diabetes in the Latino Community

Sansum Diabetes Research Institute

NCT03736486

COMPLETED NA 100 participants

Pilot Guaranteed Income Study, Philadelphia, April 2023

University of Pennsylvania

NCT05838027

COMPLETED Phase 4 87 participants

Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication

University of Maryland, Baltimore

NCT03823911

COMPLETED NA 87 participants

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

Duke University

NCT01343810

COMPLETED NA 85 participants

The FAITH! Trial: A mHealth Intervention to Improve Cardiovascular Health Among African-Americans

Mayo Clinic

NCT03777709

COMPLETED NA 80 participants

Hoosier Sport: Refining and Implementing a Sustainable Campus-Community Partnership in Rural Indiana

Indiana University

NCT06602596

COMPLETED Early Phase 1 80 participants

The Effect of Vitamin D Statues on Endothelial Function

University of Wisconsin, Madison

NCT01049048

COMPLETED NA 71 participants

Evaluation of a Lifestyle Medicine Practice

Ohio University

NCT03739034

COMPLETED Phase 4 70 participants

Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome

Florida Atlantic University

NCT00272311

COMPLETED Phase 1 67 participants

Effects of NT-0796 in Obese Participants at Risk of Cardiovascular Disease

NodThera Limited

NCT06129409

COMPLETED Phase 2 66 participants

Pistachios Blood Sugar Control, Heart and Gut Health

Penn State University

NCT04056208

COMPLETED NA 65 participants

Singing and Cardiovascular Health in Older Adults

Medical College of Wisconsin

NCT04121741

COMPLETED 60 participants

The Singing Heart Study

Medical College of Wisconsin

NCT03805529

COMPLETED Phase 2 55 participants

Antiplatelet Therapy in HIV

NYU Langone Health

NCT02559414

COMPLETED Phase 4 52 participants

Impact of Statin Therapy on Adaptations to Aerobic Exercise

University of Kansas Medical Center

NCT03360916

COMPLETED NA 50 participants

Eggs as Part of a Healthy Breakfast

University of Connecticut

NCT02297464

COMPLETED NA 50 participants

Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure

University of California, Los Angeles

NCT05637970

COMPLETED 47 participants

Effect of Diet on Vascular Disease in Pre-Menopausal Women

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00484861

COMPLETED Phase 4 46 participants

Oral Contraceptives in the Metabolic Syndrome

Virginia Commonwealth University

NCT00205504

COMPLETED Phase 4 45 participants

Dapagliflozin and Measures of Cardiovascular Autonomic Function in Patients With Type 2 Diabetes (T2D)

University of Michigan

NCT02973477

COMPLETED NA 45 participants

ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study

University of California, San Francisco

NCT04709549

COMPLETED NA 40 participants

NightWare and Cardiovascular Health in Adults With PTSD

University of Colorado, Denver

NCT05365607

COMPLETED NA 40 participants

Growing Healthy Hearts: An Online Gardening Program for Adults With Risk Factors for Cardiovascular Disease

Milton S. Hershey Medical Center

NCT05720611

COMPLETED NA 40 participants

Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery

Dartmouth-Hitchcock Medical Center

NCT04481737

COMPLETED NA 38 participants

SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial

Stanford University

NCT03718988

COMPLETED NA 35 participants

PE Audit and Feedback Pilot Study

University of California, Berkeley

NCT05509803

COMPLETED NA 35 participants

The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes

Griffin Hospital

NCT04316429

COMPLETED NA 34 participants

Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive Symptoms

University of Washington

NCT01892124

COMPLETED NA 32 participants

Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome

Ohio State University

NCT03624569

COMPLETED NA 30 participants

Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers

Tufts University

NCT00175084

COMPLETED 27 participants

Blood Pressure First Medication Therapy Management

American Pharmacists Association Foundation

NCT04275934

COMPLETED NA 25 participants

Respiratory Strength Training in Cardiac Surgical Patients

University of Florida

NCT04887415

COMPLETED NA 24 participants

Nutrition360: Moving to Integrated and Holistic Disease Prevention Among Underserved Mississippians

University of Southern Mississippi

NCT06286618

COMPLETED 24 participants

Platelet Function on Abacavir and Tenofovir

University of California, Los Angeles

NCT03081572

COMPLETED Phase 1 24 participants

MRI-Guided Balloon Angioplasty to Treat Blood Flow Blockage in the Legs

National Heart, Lung, and Blood Institute (NHLBI)

NCT00094783

COMPLETED NA 23 participants

Providing Personalized Health and Individual Lifestyle Enhancing Solutions (Prophiles) in CVD

NYU Langone Health

NCT03643146

COMPLETED NA 21 participants

Physical Activity and Pacemaker Study

Medical College of Wisconsin

NCT03052829

COMPLETED NA 21 participants

Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake

Brigham and Women's Hospital

NCT01399632

COMPLETED Phase 4 21 participants

Pilot Study of Using Copeptin to Predict Response to Tolvaptan

University of North Carolina, Chapel Hill

NCT01346072

COMPLETED NA 20 participants

Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population

Leryn Reynolds

NCT04812392

COMPLETED NA 20 participants

Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study

University of Montana

NCT06384625

COMPLETED NA 15 participants

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)

Penn State University

NCT05824741

COMPLETED NA 12 participants

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) During Pregnancy

Penn State University

NCT05822531

COMPLETED NA 11 participants

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Abbott Medical Devices

NCT03539458

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 18
Phase 3 13
Phase 4 13

Named interventions

Most-linked intervention names on Cardiovascular Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
9 trials
Placebo Dietary supplement
4 trials
Aspirin Drug
3 trials
Corus CAD (ASGES) Diagnostic test
2 trials
Medication Drug
2 trials
Tendyne Mitral Valve System Device
2 trials
Social Determinants of Health Other
2 trials
Lifestyle Behavioral
2 trials

US sites by state

Facility locations filed on Cardiovascular Diseases trials. A trial with sites in several states counts in each.

California 60 trials
Massachusetts 38 trials
New York 37 trials
Pennsylvania 36 trials
Illinois 33 trials
Florida 30 trials
Minnesota 28 trials
Georgia 27 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiovascular Diseases page

304 registered trials, 134 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 134 Cardiovascular Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Duke University sponsors the most Cardiovascular Diseases trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Diseases condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.