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Cardiovascular Diseases clinical trials
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
304 US clinical trials · 134 currently recruiting
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
The research picture
Cardiovascular Diseases has 304 registered US clinical trials, 134 of them open to new participants right now, about 44% of the total.
- 134
- recruiting participants now
- 44%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Duke University
Active & Recent Trials
304 total, page 6 of 7
Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)
University of California, San Francisco
NCT03207945
Best Rest: Rest Time Before Blood Pressure Measurement Trial
Johns Hopkins University
NCT04031768
Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen
Thomas Jefferson University
NCT03646370
Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults
Korea Ginseng Corporation
NCT06236243
Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Gabi SmartCare
NCT05319236
Distributed Registry
Stanford University
NCT03898570
Mil Familias-Santa Barbara's Operational Pilot to Understand Diabetes in the Latino Community
Sansum Diabetes Research Institute
NCT03736486
Pilot Guaranteed Income Study, Philadelphia, April 2023
University of Pennsylvania
NCT05838027
Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication
University of Maryland, Baltimore
NCT03823911
Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers
Duke University
NCT01343810
The FAITH! Trial: A mHealth Intervention to Improve Cardiovascular Health Among African-Americans
Mayo Clinic
NCT03777709
Hoosier Sport: Refining and Implementing a Sustainable Campus-Community Partnership in Rural Indiana
Indiana University
NCT06602596
The Effect of Vitamin D Statues on Endothelial Function
University of Wisconsin, Madison
NCT01049048
Evaluation of a Lifestyle Medicine Practice
Ohio University
NCT03739034
Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome
Florida Atlantic University
NCT00272311
Effects of NT-0796 in Obese Participants at Risk of Cardiovascular Disease
NodThera Limited
NCT06129409
Pistachios Blood Sugar Control, Heart and Gut Health
Penn State University
NCT04056208
Singing and Cardiovascular Health in Older Adults
Medical College of Wisconsin
NCT04121741
The Singing Heart Study
Medical College of Wisconsin
NCT03805529
Antiplatelet Therapy in HIV
NYU Langone Health
NCT02559414
Impact of Statin Therapy on Adaptations to Aerobic Exercise
University of Kansas Medical Center
NCT03360916
Eggs as Part of a Healthy Breakfast
University of Connecticut
NCT02297464
Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure
University of California, Los Angeles
NCT05637970
Effect of Diet on Vascular Disease in Pre-Menopausal Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00484861
Oral Contraceptives in the Metabolic Syndrome
Virginia Commonwealth University
NCT00205504
Dapagliflozin and Measures of Cardiovascular Autonomic Function in Patients With Type 2 Diabetes (T2D)
University of Michigan
NCT02973477
ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
University of California, San Francisco
NCT04709549
NightWare and Cardiovascular Health in Adults With PTSD
University of Colorado, Denver
NCT05365607
Growing Healthy Hearts: An Online Gardening Program for Adults With Risk Factors for Cardiovascular Disease
Milton S. Hershey Medical Center
NCT05720611
Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery
Dartmouth-Hitchcock Medical Center
NCT04481737
SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial
Stanford University
NCT03718988
PE Audit and Feedback Pilot Study
University of California, Berkeley
NCT05509803
The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT04316429
Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive Symptoms
University of Washington
NCT01892124
Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome
Ohio State University
NCT03624569
Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers
Tufts University
NCT00175084
Blood Pressure First Medication Therapy Management
American Pharmacists Association Foundation
NCT04275934
Respiratory Strength Training in Cardiac Surgical Patients
University of Florida
NCT04887415
Nutrition360: Moving to Integrated and Holistic Disease Prevention Among Underserved Mississippians
University of Southern Mississippi
NCT06286618
Platelet Function on Abacavir and Tenofovir
University of California, Los Angeles
NCT03081572
MRI-Guided Balloon Angioplasty to Treat Blood Flow Blockage in the Legs
National Heart, Lung, and Blood Institute (NHLBI)
NCT00094783
Providing Personalized Health and Individual Lifestyle Enhancing Solutions (Prophiles) in CVD
NYU Langone Health
NCT03643146
Physical Activity and Pacemaker Study
Medical College of Wisconsin
NCT03052829
Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake
Brigham and Women's Hospital
NCT01399632
Pilot Study of Using Copeptin to Predict Response to Tolvaptan
University of North Carolina, Chapel Hill
NCT01346072
Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population
Leryn Reynolds
NCT04812392
Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study
University of Montana
NCT06384625
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)
Penn State University
NCT05824741
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) During Pregnancy
Penn State University
NCT05822531
Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
Abbott Medical Devices
NCT03539458
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiovascular Diseases Trial Landscape
304 indexed Cardiovascular Diseases studies · 134 recruiting (44%).
Phase mix: 26 late (III/IV) vs 28 early (I/II).
Top sponsor: Duke University (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiovascular Diseases?
PlainTrial tracks 304 US clinical trials for Cardiovascular Diseases, of which 134 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiovascular Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.