Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03069092 · ClinicalTrials.gov registry record · NA

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise

A NA study of Cardiovascular Diseases, sponsored by Iowa State University.

Completed
Registry status
NA
Development phase
406
Enrollment target
1
Study location

NCT03069092: Completed NA study of Cardiovascular Diseases, sponsored by Iowa State University.

NCT03069092 is a NA study of Cardiovascular Diseases that has completed, run by Iowa State University. The registered enrollment target is 406 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03069092, a NA study of Cardiovascular Diseases, has completed, sponsored by Iowa State University.

COMPLETED
Registry status
NA
Development phase
406 participants
Enrollment target
1
Study location

Study Summary

As the leading cause of death, cardiovascular disease (CVD) accounts for about one-third of U.S. mortality. Physical inactivity, one of the main CVD risk factors, causes 6% of coronary heart disease worldwide. The American Heart Association has identified cardiovascular health behaviors including smoking, obesity, diet, and aerobic exercise; however, resistance exercise was not included due to the limited evidence of its efficacy. Comparatively, the cardiovascular benefits of aerobic training have been well-documented whereas the independent and additive benefits of resistance training on cardiovascular health have not been established. Thus, this project is aimed to answer one of the most common questions about exercise and health:"What type or combination of exercise is most effective for CVD prevention?" This project will significantly contribute to developing more effective CVD prevention approaches, advancing more comprehensive physical activity guidelines, and providing important insights and novel opportunities for the future science of physical activity and health.

Primary Outcome

The primary outcome is the change from baseline in the composite cardiovascular disease risk score (z-score) calculated using resting blood pressure, low-density lipoprotein cholesterol, fasting glucose, and percent body fat. Each risk factor will be individually standardized and expressed as sex-specific z-score by using the formula = (value - mean)/standard deviation for each participant.

Conditions Studied

Interventions

  • BEHAVIORAL aerobic exercise
  • BEHAVIORAL resistance exercise
  • BEHAVIORAL Combined resistance and aerobic exercise

Study Locations (1)

Iowa

  • Iowa State University - Ames

Trial Details

FieldValue
Enrollment Target 406 participants
Start Date 2017-07-01
Est. Completion 2021-04-30
Phase NA
Iowa State University

23 total trials

What the finished NCT03069092 record still lists

NCT03069092 is an interventional study that assigns participants to a tested intervention. The registered 406 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Cardiovascular Diseases appearing as the primary indexed condition, and to 3 interventions - of which aerobic exercise is the first listed.

NCT03069092 reports a single indexed study location in Iowa.

Frequently Asked Questions

What is clinical trial NCT03069092 about?

NCT03069092 is a clinical study titled "Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise". As the leading cause of death, cardiovascular disease (CVD) accounts for about one-third of U.S. mortality. Physical inactivity, one of the main CVD risk factors, causes 6% of coronary heart disease worldwide. The American Heart Association has identified cardiovascular health behaviors including sm...

What is the current status of trial NCT03069092?

This trial is currently completed. It is a NA study. The enrollment target is 406 participants. The study started on 2017-07-01. Estimated completion is 2021-04-30.

What conditions does trial NCT03069092 study?

This clinical trial studies the following conditions: Cardiovascular Diseases.

What interventions are being tested in trial NCT03069092?

The interventions under investigation include: aerobic exercise (BEHAVIORAL), resistance exercise (BEHAVIORAL), Combined resistance and aerobic exercise (BEHAVIORAL).

Who is sponsoring clinical trial NCT03069092?

This trial is sponsored by Iowa State University, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03069092 being conducted?

This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03069092's enrollment target sits among peer trials

406 105th of 300 higher than 196 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06223360 · 406 participants · Phase 2

    A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

  • NCT06411769 · 406 participants · NA

    Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas

  • NCT06585787 · 406 participants · Phase 3

    A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

  • NCT06735534 · 407 participants · NA

    Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03069092, the US trial registry maintained by the National Library of Medicine. NCT03069092 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.