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Cardiovascular Diseases clinical trials
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
304 US clinical trials · 134 currently recruiting
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
The research picture
Cardiovascular Diseases has 304 registered US clinical trials, 134 of them open to new participants right now, about 44% of the total.
- 134
- recruiting participants now
- 44%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Duke University
Active & Recent Trials
304 total, page 4 of 7
Integrating Abbott Point-of-Care Technologies and the Community Scientist Model to Support HbA1c Testing Per ADA
Sansum Diabetes Research Institute
NCT05000840
A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
University of Minnesota
NCT05671380
Clinical Markers of Dysphagia in Cardiac Surgical Patients
University of Florida
NCT05304416
CommunityRx-Cardiovascular Disease
University of North Carolina, Chapel Hill
NCT06264726
RADIANCE Continued Access Protocol
ReCor Medical
NCT05017935
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
atHeart Medical
NCT04591392
2019-06 TRISCEND Study
Edwards Lifesciences
NCT04221490
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
ReCor Medical
NCT03614260
Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)
Wake Forest University Health Sciences
NCT04617834
Behavioral Chronotype: Impact on Sleep and Metabolism
University of Chicago
NCT03647306
Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer
Abramson Cancer Center at Penn Medicine
NCT05078190
Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer
Abramson Cancer Center at Penn Medicine
NCT05096338
Collaborate and Leverage Evidence in African American Rural Network
University of North Carolina, Chapel Hill
NCT06730633
A Study of Mosliciguat in PH-ILD
Pulmovant
NCT06635850
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Inquis Medical
NCT05907564
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03520660
Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation
University of Rochester
NCT04922281
Cancer Survivor Cardiomyopathy Detection
Mayo Clinic
NCT05201014
Mindfulness App Training for Cardiovascular Health
University of Pittsburgh
NCT06152185
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Abbott Medical Devices
NCT03433274
Team-based Care to Improve Hypertension
New York University
NCT05413252
Re-thinking the Role of Peers And Training Patients [RePeAT]
University of Rochester
NCT05933655
Effects of Dark Chocolate on the Risk Factors of Cardiovascular Diseases
San Diego State University
NCT06808282
Estrogen and Microvascular Function
Medical College of Wisconsin
NCT06043310
Dietary Approaches for Cardiovascular Health Study
University of Delaware
NCT05180435
Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) Syndrome
Rutgers, The State University of New Jersey
NCT06461273
Watermelon Dose Response Blood Pressure Study
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT05892328
Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption
University of California, Davis
NCT05321277
Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial
Dana-Farber Cancer Institute
NCT07442578
Enhancing Mental and Physical Health of Women Veterans
VA Office of Research and Development
NCT05050266
AB-1002 in Patients With Class III Heart Failure
AskBio
NCT04179643
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
University of Pennsylvania
NCT05828680
A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation
Boston Scientific Corporation
NCT04147884
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
Janssen Research & Development
NCT03492580
Evaluation of VLER-Indiana Health Information Exchange Demonstration Project
VA Office of Research and Development
NCT01446705
Active Choice in the EHR to Promote Statin Therapy
University of Pennsylvania
NCT03271931
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00000620
Raloxifene Use for The Heart
Eli Lilly and Company
NCT00190593
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
University of Colorado, Denver
NCT03973931
Cooking for Health Optimization With Patients
Tulane University
NCT03443635
Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest
National Heart, Lung, and Blood Institute (NHLBI)
NCT00047411
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
NYU Langone Health
NCT01471522
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
CardioDx
NCT00500617
Virtual World-Based Cardiac Rehabilitation
Mayo Clinic
NCT05897710
Understanding the Genetic and Hereditary Basis of Atherosclerosis
Wake Forest University Health Sciences
NCT00344292
Occluded Artery Trial (OAT)
NYU Langone Health
NCT00004562
Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease
Duke University
NCT00023595
Examining How Heart Disease Risk Factors Affect Healthy Aging (The Chicago Healthy Aging Study [CHAS])
Northwestern University
NCT00626379
A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease
Duke University
NCT03936660
Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit
Geisinger Clinic
NCT03470701
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiovascular Diseases Trial Landscape
304 indexed Cardiovascular Diseases studies · 134 recruiting (44%).
Phase mix: 26 late (III/IV) vs 28 early (I/II).
Top sponsor: Duke University (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiovascular Diseases?
PlainTrial tracks 304 US clinical trials for Cardiovascular Diseases, of which 134 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiovascular Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.