Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 134 recruiting now full pipeline #27 of 28,707 conditions

Cardiovascular Diseases: full-pipeline trial registry

134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.

Corpus placement: #27 of 28,707 conditions by registered trial count.

304 US clinical trials · 134 currently recruiting · #27 of 28,707 conditions by registered trial count

Cardiovascular Diseases: 304 US clinical trials tracked, 134 recruiting.

Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.

Enrollment posture brief

Registry condition cardiovascular-diseases

OPEN 134 | RECR 44% | LATE 26 | EARLY 28 | RANK #27 | SPON 10

Nearest open-share peer: Suicide (44% recruiting · 93 trials)

Acute Myeloid Leukemia51.8%Chronic Pain46%Cardiovascular Diseases (thi…44%HIV35.9%COVID-1922.7%
Open-enrollment share among volume-matched conditions near Cardiovascular Diseases

Cardiovascular Diseases lists 134 open slots (44% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiovascular Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiovascular Diseases is recruiting above its size-band peers.

    134 of 304 indexed trials (44.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cardiovascular Diseases trials is spread across many organizations.

    Duke University accounts for 10 of 304 trials (3.3%). 159 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiovascular Diseases enrolment sits around 200 participants.

    Median target enrolment is 200 among the 301 trials that report a genuine target (sentinel values excluded). 101 of those (33.6%) plan for fewer than 100 participants.

  4. Cardiovascular Diseases research is mostly interventional.

    225 interventional and 79 observational studies make up this index (74% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 218Phase 313Phase 413

Open and recent trials

304 total, page 4 of 7

ACTIVE NOT RECRUITING 750 participants

Integrating Abbott Point-of-Care Technologies and the Community Scientist Model to Support HbA1c Testing Per ADA

Sansum Diabetes Research Institute

NCT05000840

ACTIVE NOT RECRUITING NA 700 participants

A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities

University of Minnesota

NCT05671380

ACTIVE NOT RECRUITING 347 participants

Clinical Markers of Dysphagia in Cardiac Surgical Patients

University of Florida

NCT05304416

ACTIVE NOT RECRUITING NA 325 participants

CommunityRx-Cardiovascular Disease

University of North Carolina, Chapel Hill

NCT06264726

ACTIVE NOT RECRUITING NA 300 participants

RADIANCE Continued Access Protocol

ReCor Medical

NCT05017935

ACTIVE NOT RECRUITING NA 250 participants

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

atHeart Medical

NCT04591392

ACTIVE NOT RECRUITING NA 228 participants

2019-06 TRISCEND Study

Edwards Lifesciences

NCT04221490

ACTIVE NOT RECRUITING NA 225 participants

The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

ReCor Medical

NCT03614260

ACTIVE NOT RECRUITING 215 participants

Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)

Wake Forest University Health Sciences

NCT04617834

ACTIVE NOT RECRUITING NA 200 participants

Behavioral Chronotype: Impact on Sleep and Metabolism

University of Chicago

NCT03647306

ACTIVE NOT RECRUITING 200 participants

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer

Abramson Cancer Center at Penn Medicine

NCT05078190

ACTIVE NOT RECRUITING 200 participants

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer

Abramson Cancer Center at Penn Medicine

NCT05096338

ACTIVE NOT RECRUITING NA 173 participants

Collaborate and Leverage Evidence in African American Rural Network

University of North Carolina, Chapel Hill

NCT06730633

ACTIVE NOT RECRUITING Phase 2 135 participants

A Study of Mosliciguat in PH-ILD

Pulmovant

NCT06635850

ACTIVE NOT RECRUITING NA 130 participants

Aventus Thrombectomy System Pulmonary Embolism Clinical Study

Inquis Medical

NCT05907564

ACTIVE NOT RECRUITING Phase 4 121 participants

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT03520660

ACTIVE NOT RECRUITING NA 120 participants

Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation

University of Rochester

NCT04922281

ACTIVE NOT RECRUITING 112 participants

Cancer Survivor Cardiomyopathy Detection

Mayo Clinic

NCT05201014

ACTIVE NOT RECRUITING NA 106 participants

Mindfulness App Training for Cardiovascular Health

University of Pittsburgh

NCT06152185

ACTIVE NOT RECRUITING NA 103 participants

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Abbott Medical Devices

NCT03433274

ACTIVE NOT RECRUITING NA 90 participants

Team-based Care to Improve Hypertension

New York University

NCT05413252

ACTIVE NOT RECRUITING NA 60 participants

Re-thinking the Role of Peers And Training Patients [RePeAT]

University of Rochester

NCT05933655

ACTIVE NOT RECRUITING NA 45 participants

Effects of Dark Chocolate on the Risk Factors of Cardiovascular Diseases

San Diego State University

NCT06808282

ACTIVE NOT RECRUITING 45 participants

Estrogen and Microvascular Function

Medical College of Wisconsin

NCT06043310

ACTIVE NOT RECRUITING NA 42 participants

Dietary Approaches for Cardiovascular Health Study

University of Delaware

NCT05180435

ACTIVE NOT RECRUITING NA 37 participants

Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) Syndrome

Rutgers, The State University of New Jersey

NCT06461273

ACTIVE NOT RECRUITING NA 36 participants

Watermelon Dose Response Blood Pressure Study

Clinical Nutrition Research Center, Illinois Institute of Technology

NCT05892328

ACTIVE NOT RECRUITING NA 30 participants

Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption

University of California, Davis

NCT05321277

ACTIVE NOT RECRUITING NA 20 participants

Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial

Dana-Farber Cancer Institute

NCT07442578

ACTIVE NOT RECRUITING NA 20 participants

Enhancing Mental and Physical Health of Women Veterans

VA Office of Research and Development

NCT05050266

ACTIVE NOT RECRUITING Phase 1 17 participants

AB-1002 in Patients With Class III Heart Failure

AskBio

NCT04179643

ACTIVE NOT RECRUITING 15 participants

Circadian Rhythm Disruption in the Hospital Intensive Care Environment

University of Pennsylvania

NCT05828680

ACTIVE NOT RECRUITING NA 4 participants

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Boston Scientific Corporation

NCT04147884

COMPLETED 714,582 participants

A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease

Janssen Research & Development

NCT03492580

COMPLETED 57,073 participants

Evaluation of VLER-Indiana Health Information Exchange Demonstration Project

VA Office of Research and Development

NCT01446705

COMPLETED NA 23,066 participants

Active Choice in the EHR to Promote Statin Therapy

University of Pennsylvania

NCT03271931

COMPLETED Phase 3 10,251 participants

Action to Control Cardiovascular Risk in Diabetes (ACCORD)

National Heart, Lung, and Blood Institute (NHLBI)

NCT00000620

COMPLETED Phase 3 10,000 participants

Raloxifene Use for The Heart

Eli Lilly and Company

NCT00190593

COMPLETED NA 9,501 participants

Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

University of Colorado, Denver

NCT03973931

COMPLETED Phase 1 7,192 participants

Cooking for Health Optimization With Patients

Tulane University

NCT03443635

COMPLETED Phase 3 7,001 participants

Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest

National Heart, Lung, and Blood Institute (NHLBI)

NCT00047411

COMPLETED NA 5,179 participants

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

NYU Langone Health

NCT01471522

COMPLETED 4,350 participants

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree

CardioDx

NCT00500617

COMPLETED NA 2,881 participants

Virtual World-Based Cardiac Rehabilitation

Mayo Clinic

NCT05897710

COMPLETED 2,763 participants

Understanding the Genetic and Hereditary Basis of Atherosclerosis

Wake Forest University Health Sciences

NCT00344292

COMPLETED Phase 3 2,201 participants

Occluded Artery Trial (OAT)

NYU Langone Health

NCT00004562

COMPLETED Phase 3 2,136 participants

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

Duke University

NCT00023595

COMPLETED 1,395 participants

Examining How Heart Disease Risk Factors Affect Healthy Aging (The Chicago Healthy Aging Study [CHAS])

Northwestern University

NCT00626379

COMPLETED NA 1,049 participants

A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease

Duke University

NCT03936660

COMPLETED NA 999 participants

Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit

Geisinger Clinic

NCT03470701

← Previous Page 4 of 7 Next →

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 18
Phase 3 13
Phase 4 13

Named interventions

Most-linked intervention names on Cardiovascular Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
9 trials
Placebo Dietary supplement
4 trials
Aspirin Drug
3 trials
Corus CAD (ASGES) Diagnostic test
2 trials
Medication Drug
2 trials
Tendyne Mitral Valve System Device
2 trials
Social Determinants of Health Other
2 trials
Lifestyle Behavioral
2 trials

US sites by state

Facility locations filed on Cardiovascular Diseases trials. A trial with sites in several states counts in each.

California 60 trials
Massachusetts 38 trials
New York 37 trials
Pennsylvania 36 trials
Illinois 33 trials
Florida 30 trials
Minnesota 28 trials
Georgia 27 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiovascular Diseases page

304 registered trials, 134 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 134 Cardiovascular Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Duke University sponsors the most Cardiovascular Diseases trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Diseases condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.