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NCT00224809 · ClinicalTrials.gov registry record · NA

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

A NA study of Cardiovascular Diseases and Heart Diseases, sponsored by Baylor Research Institute.

Completed
Registry status
NA
Development phase
250
Enrollment target
1
Study location

NCT00224809: Completed NA study of Cardiovascular Diseases and Heart Diseases, sponsored by Baylor Research Institute.

NCT00224809 is a NA study of Cardiovascular Diseases and Heart Diseases that has completed, run by Baylor Research Institute. The registered enrollment target is 250 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00224809, a NA study of Cardiovascular Diseases and Heart Diseases, has completed, sponsored by Baylor Research Institute.

COMPLETED
Registry status
NA
Development phase
250 participants
Enrollment target
1
Study location

Study Summary

The Transesophageal Echocardiography (TEE) Surgical Treatment of Ischemic Heart Failure (STICH) ancillary study will define the mechanism(s) of functional mitral regurgitation (MR) by TEE in patients with ischemic cardiomyopathy, and the impact of therapy (medical, coronary artery bypass grafting \[CABG\], or CABG plus surgical ventricular restoration \[SVR\]) on mechanism and severity of MR. Severity of the effect of functional MR on clinical outcomes will also be examined. The TEE STICH study will address four specific aims that will focus on defining the following: 1) the mechanism(s) of functional MR in ischemic cardiomyopathy; 2) the effect of therapy on the mechanism and severity of functional MR; 3) myocardial viability on functional MR and its response to treatment; and 4) the effect of MR on prognosis in ischemic cardiomyopathy.

Interventions

  • DRUG Aspirin
  • DRUG Spironolactone
  • DRUG Angiotensin-Converting Enzyme Inhibitors
  • PROCEDURE Coronary Artery Bypass Graft
  • DRUG Angiotensin Receptor Blockers

Study Locations (1)

Texas

  • Baylor Research Institute - Dallas

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2002-09
Est. Completion 2007-05
Phase NA
Baylor Research Institute

180 total trials

What the finished NCT00224809 record still lists

NCT00224809 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 5 interventions - of which Aspirin is the first listed.

NCT00224809 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT00224809 about?

NCT00224809 is a clinical study titled "Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation". The Transesophageal Echocardiography (TEE) Surgical Treatment of Ischemic Heart Failure (STICH) ancillary study will define the mechanism(s) of functional mitral regurgitation (MR) by TEE in patients with ischemic cardiomyopathy, and the impact of therapy (medical, coronary artery bypass grafting \[...

What is the current status of trial NCT00224809?

This trial is currently completed. It is a NA study. The enrollment target is 250 participants. The study started on 2002-09. Estimated completion is 2007-05.

What conditions does trial NCT00224809 study?

This clinical trial studies the following conditions: Cardiovascular Diseases, Heart Diseases, Coronary Disease.

What interventions are being tested in trial NCT00224809?

The interventions under investigation include: Aspirin (DRUG), Spironolactone (DRUG), Angiotensin-Converting Enzyme Inhibitors (DRUG), Coronary Artery Bypass Graft (PROCEDURE), Angiotensin Receptor Blockers (DRUG).

Who is sponsoring clinical trial NCT00224809?

This trial is sponsored by Baylor Research Institute, which has 180 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00224809 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00224809's enrollment target sits among peer trials

250 133rd of 300 higher than 164 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00224809, the US trial registry maintained by the National Library of Medicine. NCT00224809 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.