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NCT00041392 · ClinicalTrials.gov registry record · Phase 2
Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery
A Phase 2 study of Cardiovascular Diseases and Heart Diseases, sponsored by Duke University.
- Completed
- Registry status
- Phase 2
- Development phase
- 389
- Enrollment target
- 1
- Study location
NCT00041392: Completed Phase 2 study of Cardiovascular Diseases and Heart Diseases, sponsored by Duke University.
NCT00041392 is a Phase 2 study of Cardiovascular Diseases and Heart Diseases that has completed, run by Duke University. The registered enrollment target is 389 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00041392, a Phase 2 study of Cardiovascular Diseases and Heart Diseases, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 389 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine the effects of supplemental magnesium on the neurocognitive function of individuals undergoing coronary artery bypass graft (CABG) surgery.
Primary Outcome
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the cognitive test scores from baseline. We chose a four-factor solution, which represents 4 cognitive domains: verbal memory, abstraction and visuo-spatial orientation (executive function), visual memory and attention and concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 4 preoper
Conditions Studied
Interventions
- DRUG Magnesium
- DRUG 0.9% saline
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 389 participants |
| Start Date | 2001-12 |
| Est. Completion | 2009-05 |
| Phase | Phase 2 |
What the finished NCT00041392 record still lists
NCT00041392 is an interventional study that assigns participants to a tested intervention. The registered 389 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower).
The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 2 interventions - of which Magnesium is the first listed.
NCT00041392 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00041392 about?
NCT00041392 is a clinical study titled "Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery". The purpose of this study is to examine the effects of supplemental magnesium on the neurocognitive function of individuals undergoing coronary artery bypass graft (CABG) surgery.
What is the current status of trial NCT00041392?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 389 participants. The study started on 2001-12. Estimated completion is 2009-05.
What conditions does trial NCT00041392 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Heart Diseases, Coronary Disease, Neurologic Manifestations.
What interventions are being tested in trial NCT00041392?
The interventions under investigation include: Magnesium (DRUG), 0.9% saline (DRUG).
Who is sponsoring clinical trial NCT00041392?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00041392 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00041392's enrollment target sits among peer trials
389 110th of 300 higher than 191 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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