Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00583297 · ClinicalTrials.gov registry record

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial

A clinical trial of Cardiovascular Diseases and Ventricular Tachycardia, sponsored by CardioDx.

Completed
Registry status
400
Enrollment target
1
Study location

NCT00583297: Completed study of Cardiovascular Diseases and Ventricular Tachycardia, sponsored by CardioDx.

NCT00583297 is a study of Cardiovascular Diseases and Ventricular Tachycardia that has completed, run by CardioDx. The registered enrollment target is 400 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00583297, a study of Cardiovascular Diseases and Ventricular Tachycardia, has completed, sponsored by CardioDx.

COMPLETED
Registry status
400 participants
Enrollment target
1
Study location

Study Summary

The ABCD clinical study (ClinicalTrials.gov Identifier NCT00187291) was designed to determine if a T-Wave Alternans (TWA) test is equivalent to an Electrophysiology Study (EPS) in predicting life-threatening heart rhythms in patients with ischemic heart disease, left ventricular dysfunction, and non-sustained tachycardia. The purpose of the ABCD Genetic sub-study is to identify genetic markers that predict TWA status and arrhythmia risk in this same population.

Primary Outcome

Genotype and Pre-implant T-wave alternans status.

Study Locations (1)

Ohio

  • MetroHealth Medical Center - Cleveland

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2007-01
Est. Completion 2009-12
CardioDx

11 total trials

What the finished NCT00583297 record still lists

NCT00583297 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower).

The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 0 interventions.

NCT00583297 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT00583297 about?

NCT00583297 is a clinical study titled "Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial". The ABCD clinical study (ClinicalTrials.gov Identifier NCT00187291) was designed to determine if a T-Wave Alternans (TWA) test is equivalent to an Electrophysiology Study (EPS) in predicting life-threatening heart rhythms in patients with ischemic heart disease, left ventricular dysfunction, and non...

What is the current status of trial NCT00583297?

This trial is currently completed. The enrollment target is 400 participants. The study started on 2007-01. Estimated completion is 2009-12.

What conditions does trial NCT00583297 study?

This clinical trial studies the following conditions: Cardiovascular Diseases, Ventricular Tachycardia, Arrythmia, CVD.

Who is sponsoring clinical trial NCT00583297?

This trial is sponsored by CardioDx, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00583297 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00583297's enrollment target sits among peer trials

400 106th of 300 higher than 192 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01665326 · 400 participants

    Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease

  • NCT02108054 · 400 participants · NA

    Behavioral and Functional Task Development, Implementation, and Testing

  • NCT02216500 · 400 participants · NA

    Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

  • NCT02250352 · 400 participants

    Core Biopsies for Establishing a Breast Tumor Tissue Repository

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00583297, the US trial registry maintained by the National Library of Medicine. NCT00583297 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.