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NCT00605072 · ClinicalTrials.gov registry record · Phase 2
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
A Phase 2 study of Hypertension and Aging, sponsored by University of Southern California.
- Completed
- Registry status
- Phase 2
- Development phase
- 53
- Enrollment target
- 2
- Study locations
NCT00605072 is a Phase 2 study of Hypertension and Aging that has completed, run by University of Southern California. The registered enrollment target is 53 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT00605072, a Phase 2 study of Hypertension and Aging, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 53 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to examine the effects of blood pressure medications on cognition and blood flow in hypertensive elderly patients with cognitive impairment. The hypothesis is that treatment with an angiotensin receptor blocker (ARB) or an angiotensin-converting enzyme inhibitor (ACEI) will be associated with a slower rate of further cognitive decline, improved cerebral blood flow and its regulation, and preserved physical function as compared to treatment with a diuretic (HCTZ), independent of blood pressure level.
Conditions Studied
Interventions
- DRUG candesartan
- DRUG lisinopril
- DRUG hydrochlorothiazide
- DRUG nifedipine, long acting
- DRUG metoprolol, long-acting
Study Locations (2)
California
- University of Southern California - Los Angeles
Massachusetts
- Hebrew SeniorLife - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2008-01 |
| Est. Completion | 2012-12 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00605072
The ClinicalTrials.gov registry entry for NCT00605072 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower). The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Hypertension appearing as the primary indexed condition, and to 5 interventions - of which candesartan is the first listed.
NCT00605072 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00605072 about?
NCT00605072 is a clinical study titled "The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial". The purpose of this study is to examine the effects of blood pressure medications on cognition and blood flow in hypertensive elderly patients with cognitive impairment. The hypothesis is that treatment with an angiotensin receptor blocker (ARB) or an angiotensin-converting enzyme inhibitor (ACEI) w...
What is the current status of trial NCT00605072?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 2008-01. Estimated completion is 2012-12.
What conditions does trial NCT00605072 study?
This clinical trial studies the following conditions: Hypertension, Aging, Cognitive Impairment.
What interventions are being tested in trial NCT00605072?
The interventions under investigation include: candesartan (DRUG), lisinopril (DRUG), hydrochlorothiazide (DRUG), nifedipine, long acting (DRUG), metoprolol, long-acting (DRUG).
Who is sponsoring clinical trial NCT00605072?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00605072 being conducted?
This trial has 2 study locations across California, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.