Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04812392 · ClinicalTrials.gov registry record · NA

Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population

A NA study of Cardiovascular Diseases and Aging, sponsored by Leryn Reynolds.

Completed
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT04812392: Completed NA study of Cardiovascular Diseases and Aging, sponsored by Leryn Reynolds.

NCT04812392 is a NA study of Cardiovascular Diseases and Aging that has completed, run by Leryn Reynolds. The registered enrollment target is 20 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04812392, a NA study of Cardiovascular Diseases and Aging, has completed, sponsored by Leryn Reynolds.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Physical inactivity is known to increase post meal blood sugar levels in young, active populations. However, how quickly this may occur in active, older adults is not clear. Further, the relationship between blood vessel health and blood sugar disturbances which occur to acute physical inactivity is not clear. It is unknown if impairments in blood vessel function precede increases in blood sugar levels that occurs with inactivity in an aging population. This study aims to determine if short term reductions in physical activity impair blood vessel health and blood glucose control to a greater extent in an aging population compared to a young population. The investigators hypothesize that 3 days of reduced physical activity will result in impaired blood vessel function and glycemic control in an aged population.

Primary Outcome

The change in blood glucose levels measured following consumption of a meal will be assessed before inactivity and following 3 days of inactivity.

Interventions

  • DEVICE Continuous Glucose Monitoring System

Study Locations (1)

Virginia

  • Old Dominion University - Norfolk

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2021-04-01
Est. Completion 2022-01-30
Phase NA
Leryn Reynolds

1 total trials

What the finished NCT04812392 record still lists

NCT04812392 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 1 intervention - of which Continuous Glucose Monitoring System is the first listed.

NCT04812392 reports a single indexed study location in Virginia.

Frequently Asked Questions

What is clinical trial NCT04812392 about?

NCT04812392 is a clinical study titled "Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population". Physical inactivity is known to increase post meal blood sugar levels in young, active populations. However, how quickly this may occur in active, older adults is not clear. Further, the relationship between blood vessel health and blood sugar disturbances which occur to acute physical inactivity is...

What is the current status of trial NCT04812392?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2021-04-01. Estimated completion is 2022-01-30.

What conditions does trial NCT04812392 study?

This clinical trial studies the following conditions: Cardiovascular Diseases, Aging, Glucose Intolerance.

What interventions are being tested in trial NCT04812392?

The interventions under investigation include: Continuous Glucose Monitoring System (DEVICE).

Who is sponsoring clinical trial NCT04812392?

This trial is sponsored by Leryn Reynolds, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04812392 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04812392's enrollment target sits among peer trials

20 282nd of 300 higher than 14 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00573339 · 20 participants

    Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

  • NCT00692939 · 20 participants · Phase 1

    Autologous Stem Cell Transplantation for Crohn's Disease

  • NCT00967785 · 20 participants · Phase 1

    A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

  • NCT01406691 · 20 participants · Phase 4

    Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04812392, the US trial registry maintained by the National Library of Medicine. NCT04812392 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.