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NCT04128215 · ClinicalTrials.gov registry record · NA
Sex Differences in Vascular Responses to Exercise
A NA study of Aging, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04128215: Completed NA study of Aging, sponsored by University of Florida.
NCT04128215 is a NA study of Aging that has completed, run by University of Florida. The registered enrollment target is 20 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04128215, a NA study of Aging, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation. Regular aerobic exercise ameliorates endothelial dysfunction in healthy older men, but the data in healthy postmenopausal women are inconsistent with many studies showing no effect. The primary objective of this study was to examine sex differences in acute and chronic endothelial responses to exercise training in older men vs. older postmenopausal women.
Primary Outcome
Flow mediated dilation (FMD) is an established non-invasive measure of endothelial function. Brachial artery FMD was determined via ultrasonography in response to reactive hyperemia following 5-min forearm ischemia. FMD was expressed as % change and was calculated as (max diameter-baseline-diameter)/baseline diameter)\*100. The change in FMD for the control period was calculated as the difference in FMD from baseline to the end of the 8-week control period. The change in FMD for the exercise int
Conditions Studied
Interventions
- BEHAVIORAL Control Period
- BEHAVIORAL Exercise Period
Study Locations (1)
Florida
- Integrative Cardiovasculal Physiology Laboratory, University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2019-11-22 |
| Est. Completion | 2023-05-31 |
| Phase | NA |
What the finished NCT04128215 record still lists
NCT04128215 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Control Period is the first listed.
NCT04128215 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04128215 about?
NCT04128215 is a clinical study titled "Sex Differences in Vascular Responses to Exercise". A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation. Regular aerobic exercise ameliorates endothelial dysfunction in healthy older men, but the data in healthy postmenopausal women are inconsistent with many studies sho...
What is the current status of trial NCT04128215?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2019-11-22. Estimated completion is 2023-05-31.
What conditions does trial NCT04128215 study?
This clinical trial studies the following conditions: Aging.
What interventions are being tested in trial NCT04128215?
The interventions under investigation include: Control Period (BEHAVIORAL), Exercise Period (BEHAVIORAL).
Who is sponsoring clinical trial NCT04128215?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04128215 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04128215's enrollment target sits among peer trials
20 231st of 262 higher than 20 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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