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NCT03419988 · ClinicalTrials.gov registry record · NA
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise
A NA study of Aging, sponsored by Northern Arizona University.
- Completed
- Registry status
- NA
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT03419988: Completed NA study of Aging, sponsored by Northern Arizona University.
NCT03419988 is a NA study of Aging that has completed, run by Northern Arizona University. The registered enrollment target is 46 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03419988, a NA study of Aging, has completed, sponsored by Northern Arizona University.
- COMPLETED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
Advanced age is the main risk factor for chronic diseases such as cardiovascular disease, type 2 diabetes, Alzheimer's disease and cancer. One reason may be due to decreased resistance to oxidative stress as antioxidant defenses and cell protection is reduced with aging. This has been shown in animal studies and also that the impairment can be somewhat restored with exercise. This will be the first study to test this in humans by comparing young and older inactive adults before and after an exercise intervention, a practical and cost-effective intervention that can have tremendous public health impact by lowering risk for disease and medical-related costs.
Primary Outcome
Nuclear Nrf2 protein content in peripheral mononuclear cells (PBMCs) in response to acute exercise
Conditions Studied
Interventions
- BEHAVIORAL Exercise Intervention
Study Locations (1)
Arizona
- Northern Arizona University - Flagstaff
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2020-06-30 |
| Phase | NA |
What the finished NCT03419988 record still lists
NCT03419988 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Exercise Intervention is the first listed.
NCT03419988 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT03419988 about?
NCT03419988 is a clinical study titled "Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise". Advanced age is the main risk factor for chronic diseases such as cardiovascular disease, type 2 diabetes, Alzheimer's disease and cancer. One reason may be due to decreased resistance to oxidative stress as antioxidant defenses and cell protection is reduced with aging. This has been shown in anima...
What is the current status of trial NCT03419988?
This trial is currently completed. It is a NA study. The enrollment target is 46 participants. The study started on 2017-06-01. Estimated completion is 2020-06-30.
What conditions does trial NCT03419988 study?
This clinical trial studies the following conditions: Aging.
What interventions are being tested in trial NCT03419988?
The interventions under investigation include: Exercise Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT03419988?
This trial is sponsored by Northern Arizona University, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03419988 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03419988's enrollment target sits among peer trials
46 161st of 262 higher than 98 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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