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NCT05585762 · ClinicalTrials.gov registry record · NA
Buck Institute Ketone Ester RCT
A NA study of Aging and Safety Issues, sponsored by Buck Institute for Research on Aging.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05585762: Completed NA study of Aging and Safety Issues, sponsored by Buck Institute for Research on Aging.
NCT05585762 is a NA study of Aging and Safety Issues that has completed, run by Buck Institute for Research on Aging. The registered enrollment target is 30 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05585762, a NA study of Aging and Safety Issues, has completed, sponsored by Buck Institute for Research on Aging.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults. This randomized, double-blind, placebo-controlled trial aims to characterize the tolerability and safety of daily consumption of the KE in healthy older adults (over 65 years old) over 12 weeks. Study participants will complete Beverage Tolerability Questionaires (BTQ) to rate any side side effects throughout the study. Safety will also be assessed by collection of blood and urine samples, vital signs, body weight, and monitoring of adverse events (AEs). The study will also collect pilot data to explore possible effects of KE on physical function, cognitive function and quality of life. The findings of this study will be used to facilitate future mechanistic studies of KE in aging.
Primary Outcome
The primary outcome measure is the proportion of subjects reporting the same moderate to severe symptom (among dizziness, headache or nausea) occurring on more than one day within any given recall period (after week 0 - 2 acclimation period) when ketone esters are consumed daily for 12 weeks.
Conditions Studied
Interventions
- OTHER Ketone ester
- OTHER Non-ketone placebo
Study Locations (1)
California
- Buck Institute for Research on Aging - Novato
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-11-28 |
| Est. Completion | 2024-01-17 |
| Phase | NA |
What the finished NCT05585762 record still lists
NCT05585762 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Ketone ester is the first listed.
NCT05585762 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05585762 about?
NCT05585762 is a clinical study titled "Buck Institute Ketone Ester RCT". This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults. This randomized, double-blind, placebo-controlled trial aims to characterize the tolerability and safety of daily consumption of the KE in healthy older adu...
What is the current status of trial NCT05585762?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2022-11-28. Estimated completion is 2024-01-17.
What conditions does trial NCT05585762 study?
This clinical trial studies the following conditions: Aging, Safety Issues, Tolerance.
What interventions are being tested in trial NCT05585762?
The interventions under investigation include: Ketone ester (OTHER), Non-ketone placebo (OTHER).
Who is sponsoring clinical trial NCT05585762?
This trial is sponsored by Buck Institute for Research on Aging, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05585762 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05585762's enrollment target sits among peer trials
30 193rd of 262 higher than 60 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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