Vanderbilt University Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Vanderbilt University Medical Center sits in the top decile of US sponsors by registered trial count (#51 of 15,742 sponsors by registered trial count).

677 total trials 130 currently recruiting 400 completed early-phase tilt top decile by trial count

Vanderbilt University Medical Center: 677 sponsored US clinical trials, 130 recruiting.

Vanderbilt University Medical Center sponsors 677 registered US clinical trials on ClinicalTrials.gov, 130 of them currently recruiting, and 400 completed. 70 of these trials are in Phase 3-4 (later-stage) and 127 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Autonomic Failure, with 9 trials.

Top-decile sponsor footprint

Vanderbilt University Medical Center ranks in the top decile of sponsors by registered trial count (#51 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 54/100

400 of 467 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

677 total, page 12 of 14

TERMINATED Phase 4

Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients

NCT02203630

TERMINATED Phase 2

Treatment of Resistant Hypertension by Prevention of T-Cell Co-Stimulation

NCT02232880

TERMINATED Phase 1

Study to Measure Relaxation From Different Types of Focused Breathing Exercises

NCT02226744

COMPLETED

Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality Improvement Project

NCT03189550

COMPLETED

Right Ventricular Metabolism in Pulmonary Arterial Hypertension

NCT02763735

COMPLETED NA

Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure

NCT02128802

COMPLETED Phase 4

Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle.

NCT02129725

COMPLETED NA

Web-based Management of Pediatric Functional Abdominal Pain

NCT02327377

COMPLETED NA

Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D

NCT02746627

COMPLETED Phase 2

Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia

NCT01960413

COMPLETED Phase 4

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

NCT01976507

COMPLETED Phase 4

Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism

NCT02034435

COMPLETED NA

Prospective Randomized Evaluation of an Ultra Conservative Approach to Implantable Defibrillator (ICD) Programming in Patients With a Left Ventricular Assist Device (LVAD).

NCT01977703

COMPLETED

Metabolic and Cardiovascular Impact of CD36 Deficiency in African Americans

NCT02126735

COMPLETED NA

Assessment of Esophageal Epithelium Integrity With Mucosal Impedance

NCT02318862

COMPLETED NA

Timing of Inguinal Hernia Repair in Premature Infants

NCT01678638

COMPLETED Phase 3

The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure

NCT01739933

COMPLETED

Adipose Tissue and Immune Activation in HIV

NCT04439448

COMPLETED Phase 1

Nicotine Treatment of Cognitive Decline in Down Syndrome

NCT01778946

COMPLETED

Mechanisms of Chronic Kidney Disease (CKD)-Induced Foam Cell Formation

NCT01671605

COMPLETED NA

Effect of Colostrum on Mucosal Immunity in Very Low Birth Weight (VLBWs) Premature Infants

NCT01776268

COMPLETED NA

Improving Outcomes After Traumatic Injury: A Goal Management Approach

NCT01714531

COMPLETED NA

Genetically Determined Response to Atenolol in Patients With Persistent Atrial Fibrillation

NCT01719367

COMPLETED NA

Framing Eighteen Coils in Cerebral Aneurysms Trial

NCT01655784

COMPLETED Early Phase 1

Biomagnetic Characterization of Gastric Dysrhythmias III

NCT03176927

COMPLETED

Vanderbilt Childhood Obesity Registry

NCT02957916

COMPLETED Phase 1

Nutrient Sensing in the Duodenum

NCT01694004

COMPLETED NA

Feasibility Study of Dynasplint to Prevent Trismus in Head and Neck Cancer

NCT01649583

COMPLETED Phase 2

Weight Loss Study for Patients With Obesity Due to Craniopharyngioma or Other Brain Tumor

NCT01484873

COMPLETED NA

Effect of Dietary Sodium Intake on Vascular Endothelium

NCT01550315

COMPLETED NA

A Clinical Trial of A Pacifier-Activated Music Player

NCT01600586

COMPLETED NA

Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome

NCT01563107

TERMINATED NA

Assessing Normal Multichannel Intraluminal Impedance (MII)-pH Parameters for Today's Population

NCT01566383

COMPLETED Phase 2

Efficacy of Granulocyte Colony Stimulating Factor (GCSF) In Patients With Dystrophic Epidermolysis Bullosa

NCT01538862

TERMINATED Phase 4

Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome

NCT01625455

COMPLETED Phase 3

The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study

NCT01211522

COMPLETED NA

Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia

NCT01117454

COMPLETED

Improving Prematurity-Related Respiratory Outcomes at Vanderbilt

NCT01460576

COMPLETED Phase 1

Ghrelin and Insulin Resistance

NCT00884494

TERMINATED Phase 4

Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema

NCT01574248

COMPLETED NA

Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass

NCT01228305

COMPLETED Phase 1

Study of Sildenafil Citrate on Insulin Resistance in African American

NCT01334554

COMPLETED NA

Precision-Based Magnesium Trial

NCT01105169

COMPLETED

Comparative Effectiveness of Operative Versus Non-Operative Treatments for Rotator Cuff Tears

NCT02287090

COMPLETED

Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension

NCT01316666

COMPLETED

Assessment of Vascular Endothelial Function in Postural Tachycardia Syndrome

NCT01308099

COMPLETED NA

Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas

NCT01145365

COMPLETED

Vertical Expandable Prosthetic Titanium Rib (VEPTR) for Thoracic Insufficiency Syndrome

NCT02241954

COMPLETED NA

ST-segment Elevation as an AF Endophenotype

NCT01205529

COMPLETED

Biology in Patients With Reflux Esophagitis

NCT01194323

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Phase Distribution

PhaseTrial count
Phase 1 65
Phase 2 62
Phase 3 14
Phase 4 56

What is open in the Vanderbilt University Medical Center pipeline

130 recruiting of 677 indexed (19% open); 400 completed (59%).

Phase mix: 70 late (III/IV) vs 127 early (I/II) (early-phase heavy).

Top condition: Autonomic Failure (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Vanderbilt University Medical Center: open-pipeline peers nationwide

Peers matched on 677 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 01,0002,0003,000 12%14%16%18%20%22%24% Total trials Recruiting share Vanderbilt University Medical CenterThe Cleveland ClinicUniversity of California, DavisWeill Medical College of Cornell UniversityIcahn School of Medicine at Mount SinaiCalifornia Polytechnic State University-San Luis ObispoPhoenix Children's HospitalMayo ClinicUniversity of South Carolina
Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 677 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this Vanderbilt University Medical Center page

677 registered trials is a research-attention snapshot, not an endorsement of Vanderbilt University Medical Center or any single study.

  • 130 of Vanderbilt University Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Autonomic Failure is the condition Vanderbilt University Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Autonomic Failure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Vanderbilt University Medical Center pipeline card: 677 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.