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2026 data Public-data reference. official source

Tourette Syndrome

Open-data reference.

34 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING 351 participants

Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder

Vanderbilt University Medical Center

NCT06576726

RECRUITING 214 participants

Sensory Symptoms in Tourette Syndrome

Vanderbilt University Medical Center

NCT03851484

RECRUITING NA 150 participants

Remote Delivery of a Mindfulness-based Intervention for Tics

Johns Hopkins University

NCT06408662

RECRUITING 140 participants

Longitudinal Impact of Stressors in Adults With Tourette Syndrome

Vanderbilt University Medical Center

NCT04851678

RECRUITING Phase 2 100 participants

Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

University of Minnesota

NCT06194305

RECRUITING 100 participants

A Multicenter Pediatric Deep Brain Stimulation Registry

Boston Children's Hospital

NCT06585618

RECRUITING Phase 2 60 participants

CBIT+TMS R33 Phase

University of Minnesota

NCT06678737

RECRUITING NA 30 participants

Trajectories of Change in Tourette Syndrome

University of Minnesota

NCT06679790

RECRUITING NA 20 participants

Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study

West Virginia University

NCT05705999

RECRUITING NA 12 participants

Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder

University of Utah

NCT06385535

ACTIVE NOT RECRUITING NA 250 participants

Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals

Massachusetts General Hospital

NCT01075672

ACTIVE NOT RECRUITING Phase 2 164 participants

Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome

Noema Pharma

NCT06315751

ACTIVE NOT RECRUITING Phase 3 150 participants

A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder

Emalex Biosciences

NCT06021522

ACTIVE NOT RECRUITING NA 8 participants

Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression

University of Florida

NCT05371041

COMPLETED 250 participants

Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder

Vanderbilt University Medical Center

NCT04335175

COMPLETED Phase 3 158 participants

A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)

Teva Branded Pharmaceutical Products R&D

NCT03571256

COMPLETED Phase 2 120 participants

Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children

Tourette Association of America

NCT00218777

COMPLETED 66 participants

Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome

Vanderbilt University Medical Center

NCT04449003

COMPLETED Phase 2 63 participants

Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria

Boehringer Ingelheim

NCT00558467

COMPLETED 54 participants

Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00056420

COMPLETED 54 participants

Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00755339

COMPLETED NA 50 participants

Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics

University of Minnesota

NCT04578912

COMPLETED 43 participants

Tourette Discrimination (TD) Stigma Scale

Wake Forest University Health Sciences

NCT05696769

COMPLETED 42 participants

Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00081419

COMPLETED Phase 4 39 participants

Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission

Johns Hopkins University

NCT01018056

COMPLETED Phase 4 34 participants

Guanfacine in Children With Tic Disorders

Yale University

NCT01547000

COMPLETED NA 31 participants

Open-label MNS for Tourette Syndrome

Washington University School of Medicine

NCT05016765

COMPLETED NA 21 participants

Neurofeedback for Tourette Syndrome

Yale University

NCT01702077

COMPLETED NA 21 participants

Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome

Weill Medical College of Cornell University

NCT02067819

COMPLETED Phase 1 20 participants

Developing Cognitive Training for Tourette Syndrome

University of Wisconsin, Milwaukee

NCT01440023

COMPLETED Phase 2 20 participants

Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome

Yale University

NCT00529308

COMPLETED NA 12 participants

Repetitive Transcranial Magnetic Stimulation to Reduce Tics

Children's Hospital Medical Center, Cincinnati

NCT01258790

COMPLETED Phase 1 10 participants

Open-Trial of EPI-743 for Adults With Tourette Syndrome

Yale University

NCT01719523

COMPLETED NA 5 participants

Brain Stimulation for the Treatment of Tourette Syndrome

University of Florida

NCT01329198

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 6
Phase 3 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tourette Syndrome Trial Landscape

ClinicalTrials.gov lists 34 US studies indexed under Tourette Syndrome, and 10 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Tourette Syndrome shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Tourette Syndrome is led by Vanderbilt University Medical Center with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 34 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tourette Syndrome?

PlainTrial tracks 34 US clinical trials for Tourette Syndrome, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tourette Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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