Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Tourette Syndrome
Open-data reference.
34 US clinical trials · 10 currently recruiting
Active & Recent Trials
Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
Vanderbilt University Medical Center
NCT06576726
Sensory Symptoms in Tourette Syndrome
Vanderbilt University Medical Center
NCT03851484
Remote Delivery of a Mindfulness-based Intervention for Tics
Johns Hopkins University
NCT06408662
Longitudinal Impact of Stressors in Adults With Tourette Syndrome
Vanderbilt University Medical Center
NCT04851678
Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
University of Minnesota
NCT06194305
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
CBIT+TMS R33 Phase
University of Minnesota
NCT06678737
Trajectories of Change in Tourette Syndrome
University of Minnesota
NCT06679790
Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study
West Virginia University
NCT05705999
Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
University of Utah
NCT06385535
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome
Noema Pharma
NCT06315751
A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder
Emalex Biosciences
NCT06021522
Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression
University of Florida
NCT05371041
Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
Vanderbilt University Medical Center
NCT04335175
A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)
Teva Branded Pharmaceutical Products R&D
NCT03571256
Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
Tourette Association of America
NCT00218777
Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
Vanderbilt University Medical Center
NCT04449003
Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria
Boehringer Ingelheim
NCT00558467
Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00056420
Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00755339
Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics
University of Minnesota
NCT04578912
Tourette Discrimination (TD) Stigma Scale
Wake Forest University Health Sciences
NCT05696769
Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00081419
Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission
Johns Hopkins University
NCT01018056
Guanfacine in Children With Tic Disorders
Yale University
NCT01547000
Open-label MNS for Tourette Syndrome
Washington University School of Medicine
NCT05016765
Neurofeedback for Tourette Syndrome
Yale University
NCT01702077
Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome
Weill Medical College of Cornell University
NCT02067819
Developing Cognitive Training for Tourette Syndrome
University of Wisconsin, Milwaukee
NCT01440023
Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome
Yale University
NCT00529308
Repetitive Transcranial Magnetic Stimulation to Reduce Tics
Children's Hospital Medical Center, Cincinnati
NCT01258790
Open-Trial of EPI-743 for Adults With Tourette Syndrome
Yale University
NCT01719523
Brain Stimulation for the Treatment of Tourette Syndrome
University of Florida
NCT01329198
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Tourette Syndrome Trial Landscape
ClinicalTrials.gov lists 34 US studies indexed under Tourette Syndrome, and 10 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Tourette Syndrome shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Tourette Syndrome is led by Vanderbilt University Medical Center with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 34 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Tourette Syndrome?
PlainTrial tracks 34 US clinical trials for Tourette Syndrome, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Tourette Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.