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Tourette Syndrome: early-phase trial registry
10 of 34 indexed Tourette Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #451 of 28,707 conditions by registered trial count.
34 US clinical trials · 10 currently recruiting · #451 of 28,707 conditions by registered trial count
Tourette Syndrome: 34 US clinical trials tracked, 10 recruiting.
Tourette Syndrome is the subject of 34 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 5 of these trials.
Enrollment posture brief
Registry condition tourette-syndrome
OPEN 10 | RECR 29% | LATE 4 | EARLY 8 | RANK #451 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Addiction (29% recruiting · 17 trials)
Tourette Syndrome lists 10 open slots (29% of 34 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Tourette Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Tourette Syndrome is recruiting below its size-band peers.
10 of 34 indexed trials (29.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Tourette Syndrome trials is spread across many organizations.
Vanderbilt University Medical Center accounts for 5 of 34 trials (14.7%). 20 distinct sponsors appear on at least one study for this condition label.
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Most Tourette Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 34 trials that report a genuine target (sentinel values excluded). 22 of those (64.7%) plan for fewer than 100 participants.
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Tourette Syndrome research is mostly interventional.
24 interventional and 10 observational studies make up this index (70.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
34 total, page 1 of 1
Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
Vanderbilt University Medical Center
NCT06576726
Sensory Symptoms in Tourette Syndrome
Vanderbilt University Medical Center
NCT03851484
Remote Delivery of a Mindfulness-based Intervention for Tics
Johns Hopkins University
NCT06408662
Longitudinal Impact of Stressors in Adults With Tourette Syndrome
Vanderbilt University Medical Center
NCT04851678
Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
University of Minnesota
NCT06194305
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
CBIT+TMS R33 Phase
University of Minnesota
NCT06678737
Trajectories of Change in Tourette Syndrome
University of Minnesota
NCT06679790
Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study
West Virginia University
NCT05705999
Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
University of Utah
NCT06385535
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome
Noema Pharma
NCT06315751
A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder
Emalex Biosciences
NCT06021522
Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression
University of Florida
NCT05371041
Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
Vanderbilt University Medical Center
NCT04335175
A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)
Teva Branded Pharmaceutical Products R&D
NCT03571256
Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
Tourette Association of America
NCT00218777
Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
Vanderbilt University Medical Center
NCT04449003
Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria
Boehringer Ingelheim
NCT00558467
Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00056420
Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00755339
Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics
University of Minnesota
NCT04578912
Tourette Discrimination (TD) Stigma Scale
Wake Forest University Health Sciences
NCT05696769
Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00081419
Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission
Johns Hopkins University
NCT01018056
Guanfacine in Children With Tic Disorders
Yale University
NCT01547000
Open-label MNS for Tourette Syndrome
Washington University School of Medicine
NCT05016765
Neurofeedback for Tourette Syndrome
Yale University
NCT01702077
Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome
Weill Medical College of Cornell University
NCT02067819
Developing Cognitive Training for Tourette Syndrome
University of Wisconsin, Milwaukee
NCT01440023
Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome
Yale University
NCT00529308
Repetitive Transcranial Magnetic Stimulation to Reduce Tics
Children's Hospital Medical Center, Cincinnati
NCT01258790
Open-Trial of EPI-743 for Adults With Tourette Syndrome
Yale University
NCT01719523
Brain Stimulation for the Treatment of Tourette Syndrome
University of Florida
NCT01329198
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Tourette Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Tourette Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Tourette Syndrome page
34 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 10 Tourette Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University Medical Center sponsors the most Tourette Syndrome trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tourette Syndrome condition card totals 34 registered trials; most-linked intervention Placebo; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.