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NCT01563107 · ClinicalTrials.gov registry record · NA
Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome
A NA study of Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 38
- Enrollment target
- 1
- Study location
NCT01563107 is a NA study of Postural Orthostatic Tachycardia Syndrome that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 38 participants, below the 9,241-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01563107, a NA study of Postural Orthostatic Tachycardia Syndrome, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with Postural Tachycardia Syndrome (POTS) may not adequately expand their plasma volume in response to a high sodium diet. Mechanisms involved in the regulation of plasma volume, such as the renin-angiotensin-aldosterone system and renal dopamine (DA), may be impaired in POTS and may respond inappropriately to changes in dietary sodium. The investigators propose that the changes in urinary sodium and dopamine excretion caused by consuming low-sodium and high-sodium diets will be different between patients with POTS and healthy volunteers. The purpose of this study is to determine (1) whether changes in dietary sodium level appropriately influence sodium excretion in POTS; (2) whether changes in dietary sodium level appropriately influence DA excretion in POTS; (3) whether a high dietary sodium level appropriately expands plasma volume in POTS; and (4) whether patients with POTS have improvements in their orthostatic tachycardia and symptoms as a result of a high dietary sodium level.
Conditions Studied
Interventions
- RADIATION Plasma Volume
- PROCEDURE Exercise Capacity Test - Bicycle
- PROCEDURE Posture Study
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2012-03 |
| Est. Completion | 2020-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01563107
The ClinicalTrials.gov registry entry for NCT01563107 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 9,241-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (100% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Postural Orthostatic Tachycardia Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Plasma Volume is the first listed.
NCT01563107 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT01563107 about?
NCT01563107 is a clinical study titled "Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome". Patients with Postural Tachycardia Syndrome (POTS) may not adequately expand their plasma volume in response to a high sodium diet. Mechanisms involved in the regulation of plasma volume, such as the renin-angiotensin-aldosterone system and renal dopamine (DA), may be impaired in POTS and may respon...
What is the current status of trial NCT01563107?
This trial is currently completed. It is a NA study. The enrollment target is 38 participants. The study started on 2012-03. Estimated completion is 2020-12.
What conditions does trial NCT01563107 study?
This clinical trial studies the following conditions: Postural Orthostatic Tachycardia Syndrome.
What interventions are being tested in trial NCT01563107?
The interventions under investigation include: Plasma Volume (RADIATION), Exercise Capacity Test - Bicycle (PROCEDURE), Posture Study (PROCEDURE).
Who is sponsoring clinical trial NCT01563107?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01563107 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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