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NCT01316666 · ClinicalTrials.gov registry record
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
A clinical trial, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- 50
- Enrollment target
NCT01316666: Completed study, sponsored by Vanderbilt University Medical Center.
NCT01316666 is a clinical trial that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01316666 has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
The autonomic or automatic nervous system helps control blood pressure. Diseases of the autonomic nervous system may result in a drop in blood pressure on standing in many cases leading to fainting. Diseases that affect the autonomic nervous system include pure autonomic failure, multiple system atrophy and Parkinson's disease, and can present with very similar symptoms and it is sometimes difficult to determine an exact diagnosis. The purpose of the study is to find out if the blood pressure response from taking a single dose of the medication atomoxetine can help in the diagnosis of these diseases.
Primary Outcome
Probable MSA - PAF with urinary incontinence or an orthostatic decrease of 30 mmHG in systolic blood pressure within 3 minutes of standing and poorly levodopa responsive parkinsonism or a cerebellar syndome. For Possible MSA - parkinsonism or a cerebellar syndrome and one additional feature. Probable PAF - orthostatic hypotension and impaired autonomic reflexes in the absence of clinical signs or symptoms of neurodegeneration. For Parkinson's Disease: diagnosed based on the United Kingdom Par
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2011-03 |
| Est. Completion | 2016-12 |
What the finished NCT01316666 record still lists
NCT01316666 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01316666 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01316666 about?
NCT01316666 is a clinical study titled "Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension". The autonomic or automatic nervous system helps control blood pressure. Diseases of the autonomic nervous system may result in a drop in blood pressure on standing in many cases leading to fainting. Diseases that affect the autonomic nervous system include pure autonomic failure, multiple system atr...
What is the current status of trial NCT01316666?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2011-03. Estimated completion is 2016-12.
Who is sponsoring clinical trial NCT01316666?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
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