Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00884494 · ClinicalTrials.gov registry record · Phase 1

Ghrelin and Insulin Resistance

A Phase 1 study, sponsored by Vanderbilt University Medical Center.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT00884494: Completed Phase 1 study, sponsored by Vanderbilt University Medical Center.

NCT00884494 is a Phase 1 study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00884494, a Phase 1 study, has completed, sponsored by Vanderbilt University Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

Ghrelin, a hormone produced in the stomach that stimulates hunger and food intake, declines immediately after weight loss surgery. Some studies suggest that ghrelin may worsen an individual's ability to respond to insulin. The purpose of this study is to determine if the decline in ghrelin levels after weight loss surgery contributes to the improvement of insulin sensitivity.

Interventions

  • DRUG Ghrelin infusion to assess effects on insulin sensitivity

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2011-08
Est. Completion 2014-05
Phase Phase 1

What the finished NCT00884494 record still lists

NCT00884494 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 1 intervention - of which Ghrelin infusion to assess effects on insulin sensitivity is the first listed.

NCT00884494 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00884494 about?

NCT00884494 is a clinical study titled "Ghrelin and Insulin Resistance". Ghrelin, a hormone produced in the stomach that stimulates hunger and food intake, declines immediately after weight loss surgery. Some studies suggest that ghrelin may worsen an individual's ability to respond to insulin. The purpose of this study is to determine if the decline in ghrelin levels af...

What is the current status of trial NCT00884494?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2011-08. Estimated completion is 2014-05.

What interventions are being tested in trial NCT00884494?

The interventions under investigation include: Ghrelin infusion to assess effects on insulin sensitivity (DRUG).

Who is sponsoring clinical trial NCT00884494?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00884494's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00573339 · 20 participants

    Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

  • NCT00692939 · 20 participants · Phase 1

    Autologous Stem Cell Transplantation for Crohn's Disease

  • NCT00967785 · 20 participants · Phase 1

    A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

  • NCT01406691 · 20 participants · Phase 4

    Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00884494, the US trial registry maintained by the National Library of Medicine. NCT00884494 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.